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Lumbalpunktion

Spinal tap

Eine Lumbalpunktion wird zur Diagnose von Meningitis und einigen anderen Erkrankungen des Gehirns und Rückenmarks verwendet.

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Hinweis: the information below is a general guide only. The arrangements, and the way tests are performed, may vary between different hospitals. Always follow the instructions given by your doctor, specialist, or local hospital.

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What is a lumbar puncture?

A lumbar puncture (sometimes called a spinal tap) is a procedure where a sample of cerebrospinal fluid (CSF) is taken for testing. CSF is the fluid that surrounds the brain (cerebrum) and spinal cord. This test is most commonly used to diagnose meningitis (an infection of the meninges - the structure that surrounds the brain and spinal cord). It is also used to help diagnose some other conditions of the brain, spinal cord and central nervous system, including a subarachnoid haemorrhage which is a type of bleed inside the brain.

If you, or your child, is admitted to hospital with symptoms that could be caused by meningitis then a lumbar puncture may be done urgently, either in the emergency department or very soon after your admission to a ward. Alternatively, you might be admitted for a planned lumbar puncture, as part of the diagnostic process for a long-term (chronic) neurological condition.

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Usually you lie on a couch on your side with your knees pulled up against your chest. Sometimes it is done with you sitting up and leaning forwards on some pillows. The doctor or nurse will clean an area of your lower back with antiseptic.

They will then inject some local anaesthetic into a small area of skin which lies over a space between two lower spinal bones (vertebrae). This stings a little at first but then makes the skin numb.

The doctor then pushes a thin hollow needle through the skin and tissues between two vertebrae into the space around the spinal cord which is filled with CSF. Because the skin is numbed with local anaesthetic, most people do not feel pain. You may feel pressure as the needle is inserted. However, some people do have a sharp feeling in the back or leg when the needle is pushed through.

Procedure method

Lumbalpunktion

Some fluid leaks back through the needle and is collected in a sterile pot. If you have possible meningitis, this fluid sample is sent to the laboratory to be examined under the microscope to look for germs (bacteria), red blood cells and white blood cells, which are a sign of infection. It is also 'cultured' to see if any bacteria grow and what type they are.

The fluid can also be tested for protein, sugar and other chemicals if necessary. Sometimes the doctor will also measure the fluid pressure. This is done by attaching a special tube to the needle, which can measure the pressure of the fluid coming out.

The needle is usually in for about 1-2 minutes. As soon as the required amount of fluid is collected, the needle is taken out and a sticking plaster put over the site of needle entry.

In total the procedure will take about 30-45 minutes; this includes the time to get you ready in the correct position and set up all the equipment.

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Some people develop a post lumbar puncture headache. This usually goes after a few hours. It is best to lie down for a few hours after the test, as this makes a headache less likely to develop. There is also risk of infection or bleeding at the needle puncture site and although rare, some damage to the spinal cord or brain may occur as a result on a lumbar puncture. It is very important that you tell the doctor if you are taking anticoagulants (blood-thinning drugs) so that they can take any necessary precautions to reduce the risk of bleeding.

It is sensible to stay lying flat for a period of time after a lumbar puncture - the doctor who does it will tell you how long. They will usually advise you not to operate heavy machinery or drive for at lest 24 hours and not to play sport or do any strenuous activities for at least a week.

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Genetische Tests

Tests und Untersuchungen

Genetische Tests

Genetische Tests sind eine Art medizinischer Tests, die Veränderungen in Chromosomen, Genen oder Proteinen erkennen. Genetische Tests untersuchen die DNA einer Person auf verschiedene Weisen, um die genetische Gesundheit zu beurteilen. Sie sind alle darauf ausgelegt, ein bestimmtes Gen zu identifizieren, das eine genetische Störung verursachen könnte. Wir alle haben 46 Chromosomen in unseren Zellen. Chromosomen bestehen aus DNA (Desoxyribonukleinsäure). Gene sind kurze Abschnitte der DNA, und jedes Chromosom enthält Hunderte bis Tausende von Genen. Gene enthalten die Informationen, die unser Körper benötigt, um chemische Substanzen namens Proteine herzustellen. Proteine bilden die Struktur unseres Körpers und spielen eine wichtige Rolle bei den Prozessen, die uns am Leben erhalten. Es sind die Unterschiede in unseren Genen, die uns alle individuell machen. Manchmal kann sich ein Gen verändern (dies nennt man eine Mutation) und entweder eine Krankheit verursachen oder das Risiko dafür erhöhen. Hinweis: Die unten stehenden Informationen sind nur eine allgemeine Orientierung. Die Anordnungen und die Durchführung der Tests können zwischen verschiedenen Krankenhäusern variieren. Befolgen Sie stets die Anweisungen Ihres Arztes oder des örtlichen Krankenhauses.

von Dr. Colin Tidy, MRCGP

Spirometrie

Tests und Untersuchungen

Spirometrie

Spirometry is a test that can help diagnose various lung conditions, most commonly chronic obstructive pulmonary disease (COPD). Spirometry may also be used to monitor the severity of some other lung conditions and their response to treatment. Although spirometry is very useful for helping to diagnose some conditions and monitor their treatment, a normal spirometry test does not necessarily rule out some forms of lung disease as there can be periods when spirometry tests can be normal even where a lung condition exists, such as asthma. Note: the information below is a general guide only. The arrangements, and the way tests are performed, may vary between different hospitals. Always follow the instructions given by your doctor or local hospital.

von Dr. Colin Tidy, MRCGP

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