Can I take 10 and Esomeprazole together?
Drug interaction guide
Originally published 14 Mar 2026
Meets Patient’s editorial guidelines
- DownloadDownload
- Share
- Language
- Discussion
- Audio Version
Taking alcohol with esomeprazole can make your medicine less effective and worsen your symptoms. Alcohol increases the amount of acid your stomach produces, which directly works against what esomeprazole is trying to do (reduce acid). This can lead to increased heartburn, stomach pain, and indigestion. Additionally, both substances can irritate the lining of the stomach.
In this article:
Video picks for Drug interactions
Continue reading below
Why this happens
Esomeprazole is a proton pump inhibitor (PPI) designed to reduce stomach acid production. Alcohol is a known gastric irritant that stimulates the secretion of gastric acid. By drinking alcohol, you are triggering the very process the medication is meant to prevent.
What you should do
Back to contentsIt is best to avoid or strictly limit alcohol while taking esomeprazole. If you find that your symptoms (like acid reflux or stomach pain) get worse after drinking, you should stop drinking alcohol entirely. Speak to your doctor if your symptoms do not improve.
Continue reading below
Using other medicines
Back to contentsTaking multiple medicines? Our Medicines Interaction Checker helps you check whether your prescriptions, over-the-counter medicines, and supplements are safe to take together. Simply search for your medicines to see potential interactions and what to do about them.
Disclaimer
This information is for general educational purposes only and should not be relied upon as a substitute for professional medical advice. Always consult your GP, pharmacist, or another qualified healthcare professional before making decisions about your medications. Individual circumstances may vary, and only a healthcare professional who knows your medical history can provide personalised guidance.
Patient picks for Drug interactions
Treatment and medication
Can I take 150 and Zigduo together?
Taking aspirin (75mg to 150mg) with Xigduo (which contains dapagliflozin and metformin) can increase the risk of your blood sugar dropping too low (hypoglycaemia). It may also increase the risk of a rare but serious condition called lactic acidosis, where too much acid builds up in your blood.
Treatment and medication
Can I take 1.0mg and Amlodipine together?
Taking sildenafil (Viagra) and amlodipine together can cause your blood pressure to drop lower than intended. This may make you feel dizzy, lightheaded, faint, or cause a headache.
Continue reading below
Article history
The information on this page is written and peer reviewed by qualified clinicians.
14 Mar 2026 | Originally published
Ask, share, connect.
Browse discussions, ask questions, and share experiences across hundreds of health topics.
Feeling unwell?
Assess your symptoms online for free
Sign up to the Patient newsletter
Your weekly dose of clear, trustworthy health advice - written to help you feel informed, confident and in control.
By subscribing you accept our Privacy Policy. You can unsubscribe at any time. We never sell your data.