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Can I take 100 and Paracetamol together?

Drug interaction guide

There is no known interaction between 100 (assuming this refers to a 100mg dose of a standard medication or a typo for a common substance) and paracetamol. However, if '100' refers to a specific medication not named, please provide the name. If you are referring to 100% alcohol, this is a major concern.

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Why this happens

Paracetamol is primarily processed by the liver. Without a specific second substance identified as '100', there is no known mechanism for an interaction. If '100' refers to high-strength alcohol, it increases the risk of liver toxicity because both substances stress the liver's metabolic pathways.

If '100' refers to a specific medicine, please clarify the name. If you meant 100% alcohol or heavy drinking, do not take paracetamol, as this can cause severe liver damage. Always follow the dosage instructions on the paracetamol packaging (usually no more than 4 doses in 24 hours).

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Taking multiple medicines? Our Medicines Interaction Checker helps you check whether your prescriptions, over-the-counter medicines, and supplements are safe to take together. Simply search for your medicines to see potential interactions and what to do about them.

Disclaimer

This information is for general educational purposes only and should not be relied upon as a substitute for professional medical advice. Always consult your GP, pharmacist, or another qualified healthcare professional before making decisions about your medications. Individual circumstances may vary, and only a healthcare professional who knows your medical history can provide personalised guidance.

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Article history

The information on this page is written and peer reviewed by qualified clinicians.

  • 14 Mar 2026 | Originally published
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