Can I take 15 and Pregabalin together?
Drug interaction guide
Originally published 14 Mar 2026
Meets Patient’s editorial guidelines
- DownloadDownload
- Share
- Language
- Discussion
- Audio Version
Combining alcohol with pregabalin can significantly increase the side effects of both substances. You may feel extremely drowsy, dizzy, or confused. It can also lead to problems with coordination, making you more likely to fall or have an accident. In more serious cases, it can slow down your breathing or make you lose consciousness.
In this article:
Continue reading below
Why this happens
Both alcohol and pregabalin are central nervous system depressants. This means they both slow down brain activity. When taken together, their effects add up (a synergistic effect), leading to much stronger sedation and impairment than either would cause on its own.
What you should do
Back to contentsIt is best to avoid or strictly limit alcohol while taking pregabalin. Because this combination can make you very sleepy and unsteady, you should not drive, use tools, or operate machinery if you have consumed any alcohol. If you feel unusually drowsy or have difficulty breathing, seek medical help immediately.
Continue reading below
Using other medicines
Back to contentsTaking multiple medicines? Our Medicines Interaction Checker helps you check whether your prescriptions, over-the-counter medicines, and supplements are safe to take together. Simply search for your medicines to see potential interactions and what to do about them.
Disclaimer
This information is for general educational purposes only and should not be relied upon as a substitute for professional medical advice. Always consult your GP, pharmacist, or another qualified healthcare professional before making decisions about your medications. Individual circumstances may vary, and only a healthcare professional who knows your medical history can provide personalised guidance.
Patient picks for Drug interactions

Treatment and medication
Can I take 1.0mg and Amlodipine together?
Taking sildenafil (Viagra) and amlodipine together can cause your blood pressure to drop lower than intended. This may make you feel dizzy, lightheaded, faint, or cause a headache.

Treatment and medication
Can I take 7.5mg and Medikinet together?
Taking Zopiclone and Medikinet (methylphenidate) together can cause a 'tug-of-war' effect in your body. Medikinet is a stimulant designed to wake you up and help you focus, while Zopiclone is a sedative designed to make you sleepy. Taking them at the same time can make both medicines less effective. Additionally, while Medikinet is active, it may be harder for you to fall asleep, even after taking Zopiclone. In some cases, mixing stimulants and sedatives can lead to unpredictable effects on your coordination, heart rate, or mental state (such as feeling confused or agitated).
Article history
The information on this page is written and peer reviewed by qualified clinicians.
14 Mar 2026 | Originally published

Ask, share, connect.
Browse discussions, ask questions, and share experiences across hundreds of health topics.

Feeling unwell?
Assess your symptoms online for free
Sign up to the Patient newsletter
Your weekly dose of clear, trustworthy health advice - written to help you feel informed, confident and in control.
By subscribing you accept our Privacy Policy. You can unsubscribe at any time. We never sell your data.