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Can I take 20 and Brimonidine ophthalmic together?

Drug interaction guide

Taking alcohol while using brimonidine eye drops can increase the sedative effects of both substances. You may feel much more drowsy, dizzy, or sleepy than usual. It can also affect your coordination and concentration.

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Why this happens

Both alcohol and brimonidine (which is absorbed into the bloodstream even when used as eye drops) act as central nervous system depressants. When used together, they have an additive effect, meaning they strengthen each other's ability to slow down brain activity.

It is best to avoid or strictly limit alcohol while using brimonidine eye drops. Do not drive or operate machinery if you feel drowsy or dizzy. If you choose to drink, do so very cautiously to see how the combination affects you, but be aware that your reaction times and alertness will be significantly reduced.

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Taking multiple medicines? Our Medicines Interaction Checker helps you check whether your prescriptions, over-the-counter medicines, and supplements are safe to take together. Simply search for your medicines to see potential interactions and what to do about them.

Disclaimer

This information is for general educational purposes only and should not be relied upon as a substitute for professional medical advice. Always consult your GP, pharmacist, or another qualified healthcare professional before making decisions about your medications. Individual circumstances may vary, and only a healthcare professional who knows your medical history can provide personalised guidance.

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Article history

The information on this page is written and peer reviewed by qualified clinicians.

  • 14 Mar 2026 | Originally published
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