Can I take 25 and Sertraline together?

Why this happens

Both substances affect brain chemicals and are processed by the same enzymes in the liver. Cannabis can slow down how quickly the liver breaks down sertraline, leading to higher levels of the medicine in your blood. Both substances also increase serotonin activity, which can lead to overstimulation of the nervous system.

It is best to avoid using cannabis while taking sertraline. If you choose to use both, monitor yourself closely for extreme drowsiness, rapid heartbeat, or agitation. You must not drive, as it is illegal to drive with any cannabis in your system in the UK. Speak to your doctor if you feel unwell or have concerns about your mental health.

Taking multiple medicines? Our Medicines Interaction Checker helps you check whether your prescriptions, over-the-counter medicines, and supplements are safe to take together. Simply search for your medicines to see potential interactions and what to do about them.

Disclaimer

This information is for general educational purposes only and should not be relied upon as a substitute for professional medical advice. Always consult your GP, pharmacist, or another qualified healthcare professional before making decisions about your medications. Individual circumstances may vary, and only a healthcare professional who knows your medical history can provide personalised guidance.