Can I take 3.75 and Evorel sequi together?

Why this happens

Both medications have effects on the central nervous system that can add together (additive effect). Furthermore, the oestrogen in Evorel Sequi can sometimes interfere with the liver enzymes (CYP3A4) responsible for breaking down Zopiclone, which may lead to higher levels of the sleep medication in your bloodstream.

Use this combination with caution. It is best to avoid or strictly limit alcohol, as it will significantly worsen the drowsiness. Do not drive or operate machinery if you feel sleepy or dizzy. If you find you are excessively tired the next day, speak to your doctor, as they may need to adjust your Zopiclone dose.

Taking multiple medicines? Our Medicines Interaction Checker helps you check whether your prescriptions, over-the-counter medicines, and supplements are safe to take together. Simply search for your medicines to see potential interactions and what to do about them.

Disclaimer

This information is for general educational purposes only and should not be relied upon as a substitute for professional medical advice. Always consult your GP, pharmacist, or another qualified healthcare professional before making decisions about your medications. Individual circumstances may vary, and only a healthcare professional who knows your medical history can provide personalised guidance.