Can I take Accrete d3 and Venlafaxine together?
Drug interaction guide
Originally published 14 Mar 2026
Meets Patient’s editorial guidelines
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There is a potential interaction between Accrete D3 and venlafaxine that may affect your heart rhythm. Accrete D3 contains calcium, and high levels of calcium in the blood can increase the risk of a rare but serious heart rhythm problem (called QT prolongation) when taken with certain antidepressants like venlafaxine.
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Why this happens
Venlafaxine can occasionally affect the electrical activity of the heart. High levels of calcium (from the Accrete D3) can change how the heart muscle cells react to electrical signals, potentially making this heart rhythm effect more likely.
What you should do
Back to contentsIt is generally fine to take these together, but you should not exceed the dose prescribed by your doctor. If you experience any unusual heart palpitations, dizziness, or fainting, you should contact your doctor immediately. Ensure you have your routine blood tests as requested by your GP to monitor your calcium levels.
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Using other medicines
Back to contentsTaking multiple medicines? Our Medicines Interaction Checker helps you check whether your prescriptions, over-the-counter medicines, and supplements are safe to take together. Simply search for your medicines to see potential interactions and what to do about them.
Disclaimer
This information is for general educational purposes only and should not be relied upon as a substitute for professional medical advice. Always consult your GP, pharmacist, or another qualified healthcare professional before making decisions about your medications. Individual circumstances may vary, and only a healthcare professional who knows your medical history can provide personalised guidance.
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Article history
The information on this page is written and peer reviewed by qualified clinicians.
14 Mar 2026 | Originally published
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