Can I take Am and Atorvastatin together?
Drug interaction guide
Originally published 14 Mar 2026
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Taking amlodipine and atorvastatin together can increase the amount of atorvastatin in your blood. This may increase the risk of side effects, particularly muscle pain, tenderness, or weakness (a condition called myopathy). In rare cases, this can lead to a serious muscle breakdown called rhabdomyolysis.
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Why this happens
Both medicines are processed by the same enzyme in the liver (CYP3A4). Amlodipine can slow down the breakdown of atorvastatin, leading to higher levels of the statin in your body.
What you should do
Back to contentsIt is generally safe to take these together, but your doctor may choose to limit your dose of atorvastatin (often to no more than 20mg or 40mg daily) or monitor you more closely. If you experience unexplained muscle pain, tenderness, or weakness, contact your doctor immediately.
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Using other medicines
Back to contentsTaking multiple medicines? Our Medicines Interaction Checker helps you check whether your prescriptions, over-the-counter medicines, and supplements are safe to take together. Simply search for your medicines to see potential interactions and what to do about them.
Disclaimer
This information is for general educational purposes only and should not be relied upon as a substitute for professional medical advice. Always consult your GP, pharmacist, or another qualified healthcare professional before making decisions about your medications. Individual circumstances may vary, and only a healthcare professional who knows your medical history can provide personalised guidance.
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Article history
The information on this page is written and peer reviewed by qualified clinicians.
14 Mar 2026 | Originally published
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