Can I take Co-codamol and Metformin prolonged release together?

Why this happens

Codeine is an opioid that slows down the movement of the digestive system (gut motility). Since metformin prolonged-release relies on a steady transit through the gut to release the medicine properly, slowing this process down may slightly alter its absorption.

You can generally take these together, but monitor your blood sugar levels if you have diabetes. If you experience severe constipation, speak to your pharmacist or doctor, as this can affect how your diabetes medication works. Drink plenty of water and eat high-fibre foods.

Taking multiple medicines? Our Medicines Interaction Checker helps you check whether your prescriptions, over-the-counter medicines, and supplements are safe to take together. Simply search for your medicines to see potential interactions and what to do about them.

Disclaimer

This information is for general educational purposes only and should not be relied upon as a substitute for professional medical advice. Always consult your GP, pharmacist, or another qualified healthcare professional before making decisions about your medications. Individual circumstances may vary, and only a healthcare professional who knows your medical history can provide personalised guidance.