Can I take Codeine linctus and Sulfasalazine together?

Why this happens

Codeine is an opioid that slows down the muscles in the digestive tract (reduced gastrointestinal motility). Sulfasalazine relies on reaching the large intestine to be broken down into its active parts. If codeine slows the gut too much, it could theoretically alter the timing or effectiveness of the sulfasalazine.

You can generally take these together, but monitor yourself for increased constipation. Drink plenty of water and eat high-fibre foods. If you notice your bowel condition (for which you take sulfasalazine) getting worse while taking codeine, speak to your doctor or pharmacist.

Taking multiple medicines? Our Medicines Interaction Checker helps you check whether your prescriptions, over-the-counter medicines, and supplements are safe to take together. Simply search for your medicines to see potential interactions and what to do about them.

Disclaimer

This information is for general educational purposes only and should not be relied upon as a substitute for professional medical advice. Always consult your GP, pharmacist, or another qualified healthcare professional before making decisions about your medications. Individual circumstances may vary, and only a healthcare professional who knows your medical history can provide personalised guidance.