Can I take Copper and Vitamin b12 together?
Drug interaction guide
Originally published 14 Mar 2026
Meets Patient’s editorial guidelines
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Taking high doses of vitamin C (ascorbic acid) alongside vitamin B12 can break down the B12 in your digestive system, making it less effective. While copper itself does not directly block B12, it acts as a 'catalyst' that speeds up this destruction if vitamin C is also present. On its own, copper and B12 do not have a significant direct interaction, but they are often found together in multivitamin supplements where this process can occur.
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Why this happens
In the presence of copper and vitamin C, vitamin B12 (cobalamin) undergoes an oxidation-reduction reaction. The copper ions facilitate the destruction of the B12 molecule by vitamin C, converting it into inactive analogues that the body cannot use.
What you should do
Back to contentsIf you are taking separate supplements, try to take your vitamin B12 at least 2 hours apart from high-dose vitamin C or copper supplements to ensure maximum absorption. If they are combined in a single multivitamin tablet, the amount of B12 is usually adjusted by the manufacturer to account for this, but it is still best to monitor your B12 levels if you have a known deficiency.
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Using other medicines
Back to contentsTaking multiple medicines? Our Medicines Interaction Checker helps you check whether your prescriptions, over-the-counter medicines, and supplements are safe to take together. Simply search for your medicines to see potential interactions and what to do about them.
Disclaimer
This information is for general educational purposes only and should not be relied upon as a substitute for professional medical advice. Always consult your GP, pharmacist, or another qualified healthcare professional before making decisions about your medications. Individual circumstances may vary, and only a healthcare professional who knows your medical history can provide personalised guidance.
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Article history
The information on this page is written and peer reviewed by qualified clinicians.
14 Mar 2026 | Originally published
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