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Can I take Iu and Amolodipine together?

Drug interaction guide

There is no known interaction between ibuprofen and amlodipine that would make them dangerous to take together, but ibuprofen can sometimes make blood pressure medications like amlodipine slightly less effective. Ibuprofen can also increase the risk of kidney strain when taken with blood pressure tablets.

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Why this happens

Ibuprofen belongs to a group of medicines called NSAIDs. These can cause the body to hold onto salt and water, which raises blood pressure. This works against amlodipine, which is trying to lower your blood pressure. Additionally, both drugs can affect how blood flows through the kidneys.

It is generally safe to take these together for a short time (a few days). However, if you need to take ibuprofen regularly, you should tell your doctor. They may want to check your blood pressure or perform a simple blood test to check your kidney function. If you notice any swelling in your ankles or a rise in your blood pressure readings, speak to your GP.

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Taking multiple medicines? Our Medicines Interaction Checker helps you check whether your prescriptions, over-the-counter medicines, and supplements are safe to take together. Simply search for your medicines to see potential interactions and what to do about them.

Disclaimer

This information is for general educational purposes only and should not be relied upon as a substitute for professional medical advice. Always consult your GP, pharmacist, or another qualified healthcare professional before making decisions about your medications. Individual circumstances may vary, and only a healthcare professional who knows your medical history can provide personalised guidance.

Article history

The information on this page is written and peer reviewed by qualified clinicians.

  • 14 Mar 2026 | Originally published
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