Apixaban-Tabletten

About apixaban

Apixaban works by preventing your blood from clotting as quickly or as effectively as normal. It does this by blocking a substance in your blood, called 'factor Xa', which is involved in the development of blood clots.

Sometimes, harmful blood clots can form in the blood vessels of your legs, lungs, brain or heart, and cause a blockage. This is more likely to happen if you have had surgery, or if you have a fast irregular heartbeat. For many years, a medicine called Warfarin has been commonly used to help protect against this. However, people who take warfarin need to have regular blood tests to measure how quickly their blood clots. This often means that the dose of warfarin can change quite frequently. Apixaban works in a slightly different way to warfarin, so people who take apixaban do not need to have regular blood tests.

Apixaban is prescribed to treat blood clots causing deep vein thrombosis and pulmonary embolism. You may also be prescribed apixaban to help protect against recurrent blood clots, or if you have a certain type of irregular fast heartbeat known as Vorhofflimmern.

Some medicines are not suitable for people with certain conditions, and sometimes a medicine can only be used if extra care is taken. For these reasons, before you start taking apixaban it is important that your doctor knows:

• Wenn Sie schwanger sind oder stillen.

• If you have any medical problems that increase your risk of bleeding, or if you have recently had surgery.

• Wenn Sie Probleme mit der Funktionsweise Ihrer Leber oder Ihrer Nieren haben.

• Wenn Ihnen mitgeteilt wurde, dass Sie eine Erkrankung namens Antiphospholipid-Syndrom haben.

• Wenn Sie jemals eine allergische Reaktion auf ein Medikament hatten.

• Wenn Sie andere Medikamente einnehmen. Dazu gehören alle Medikamente, die Sie einnehmen und die ohne Rezept erhältlich sind, sowie pflanzliche und ergänzende Medikamente.

• Before you start the treatment, read the manufacturer's printed information leaflet from inside the pack. It will give you more information about apixaban and will provide you with a full list of the side-effects which you could experience from taking it.

• Take apixaban exactly as your doctor tells you to. It is taken twice a day, preferably in the morning and the evening. Your doctor or pharmacist will tell you which strength of tablet is right for you as there are two strengths of apixaban available - 2.5 mg and 5 mg. This information will also be printed on the label of the pack to remind you.

• Apixaban can be taken either with or without food. Swallow the tablet with a drink of water. If you have difficulty swallowing the tablet whole, you can crush the tablet and then mix it with 30 ml (two tablespoons) of water or apple juice, or alternatively, add it to some apple purée. Swallow the mixture as soon as it has been made up.

• If you forget to take a dose at the usual time, take it as soon as you remember. Try to take the correct number of doses each day, but do not take two doses together to make up for a forgotten dose.
  

• Versuchen Sie, alle regelmäßigen Termine mit Ihrem Arzt einzuhalten. So kann Ihr Arzt Ihren Fortschritt überprüfen.

• The length of the course of treatment will depend upon why you are taking the tablets, but it will either be for a few weeks, or long-term. If you have had hip or knee surgery, you will be asked to continue taking apixaban for a certain number of weeks. If you are taking it to protect you from blood clots developing (such as if you have atrial fibrillation), you will be asked to continue to take it over a longer period of time.

• If you take any medicines that you have bought without a prescription, check with a pharmacist that they are suitable to take with apixaban. This is because some medicines, such as aspirin and some anti-inflammatory painkillers, can interfere with it.

• If you are due to have an operation or dental treatment, tell the person carrying out the treatment which medicines you are taking. This is because it may become necessary for you to stop taking apixaban for a day or so.

Along with their useful effects, most medicines can cause unwanted side-effects although not everyone experiences them. The table below contains some of the most common ones associated with apixaban. The best place to find a full list of the side-effects which can be associated with your medicine, is from the manufacturer's printed information leaflet supplied with the medicine. Alternatively, you can find an example of a manufacturer's information leaflet in the reference section below. Speak with your doctor or pharmacist if any of the following continue or become troublesome.

Wichtig: if you experience any unusual bleeding, or bleeding that doesn't stop within ten minutes, speak with your doctor straightaway or go to your local accident and emergency department.

Wenn Sie andere Symptome bemerken, die Ihrer Meinung nach auf die Tabletten zurückzuführen sein könnten, sprechen Sie mit Ihrem Arzt oder Apotheker für weitere Ratschläge.

• Bewahren Sie alle Medikamente außerhalb der Reichweite und Sicht von Kindern auf.

• An einem kühlen, trockenen Ort aufbewahren, fern von direkter Hitze und Licht.