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Apixaban-Tabletten

Eliquis

You will have been prescribed apixaban either to treat a harmful clot that has formed in a blood vessel, or to prevent one from forming.

The usual dose is one tablet taken twice a day, morning and evening.

The most common side-effects are bleeding (such as nosebleeds) and anaemia.

Auf einen Blick

  • Apixaban (Eliquis) is a medicine used to prevent or treat harmful blood clots.

  • It works by blocking a substance in your blood called factor Xa, which is involved in clotting.

  • Apixaban is usually taken twice a day, with or without food.

  • Unlike warfarin, apixaban does not require regular blood tests.

  • Tell your doctor about any medical conditions or other medicines you are taking before starting apixaban.

  • Seek medical advice immediately if you experience unusual or persistent bleeding.

About apixaban

Art des Medikaments

A factor Xa inhibitor anticoagulant

Verwendet für

Um schädliche Blutgerinnsel zu verhindern oder zu behandeln

Also called (UK and USA)

Eliquis®

Verfügbar als

Tabletten

Apixaban works by preventing your blood from clotting as quickly or as effectively as normal. It does this by blocking a substance in your blood, called 'factor Xa', which is involved in the development of blood clots.

Sometimes, harmful blood clots can form in the blood vessels of your legs, lungs, brain or heart, and cause a blockage. This is more likely to happen if you have had surgery, or if you have a fast irregular heartbeat. For many years, a medicine called Warfarin has been commonly used to help protect against this. However, people who take warfarin need to have regular blood tests to measure how quickly their blood clots. This often means that the dose of warfarin can change quite frequently. Apixaban works in a slightly different way to warfarin, so people who take apixaban do not need to have regular blood tests.

Apixaban is prescribed to treat blood clots causing deep vein thrombosis and pulmonary embolism. You may also be prescribed apixaban to help protect against recurrent blood clots, or if you have a certain type of irregular fast heartbeat known as Vorhofflimmern.

Before taking apixaban

Some medicines are not suitable for people with certain conditions, and sometimes a medicine can only be used if extra care is taken. For these reasons, before you start taking apixaban it is important that your doctor knows:

  • Wenn Sie schwanger sind oder stillen.

  • If you have any medical problems that increase your risk of bleeding, or if you have recently had surgery.

  • Wenn Sie Probleme mit der Funktionsweise Ihrer Leber oder Ihrer Nieren haben.

  • Wenn Ihnen mitgeteilt wurde, dass Sie eine Erkrankung namens Antiphospholipid-Syndrom haben.

  • Wenn Sie jemals eine allergische Reaktion auf ein Medikament hatten.

  • Wenn Sie andere Medikamente einnehmen. Dazu gehören alle Medikamente, die Sie einnehmen und die ohne Rezept erhältlich sind, sowie pflanzliche und ergänzende Medikamente.

How to take apixaban tablets

  • Before you start the treatment, read the manufacturer's printed information leaflet from inside the pack. It will give you more information about apixaban and will provide you with a full list of the side-effects which you could experience from taking it.

  • Take apixaban exactly as your doctor tells you to. It is taken twice a day, preferably in the morning and the evening. Your doctor or pharmacist will tell you which strength of tablet is right for you as there are two strengths of apixaban available - 2.5 mg and 5 mg. This information will also be printed on the label of the pack to remind you.

  • Apixaban can be taken either with or without food. Swallow the tablet with a drink of water. If you have difficulty swallowing the tablet whole, you can crush the tablet and then mix it with 30 ml (two tablespoons) of water or apple juice, or alternatively, add it to some apple purée. Swallow the mixture as soon as it has been made up.

  • If you forget to take a dose at the usual time, take it as soon as you remember. Try to take the correct number of doses each day, but do not take two doses together to make up for a forgotten dose.

Das Beste aus Ihrer Behandlung herausholen

  • Versuchen Sie, alle regelmäßigen Termine mit Ihrem Arzt einzuhalten. So kann Ihr Arzt Ihren Fortschritt überprüfen.

  • The length of the course of treatment will depend upon why you are taking the tablets, but it will either be for a few weeks, or long-term. If you have had hip or knee surgery, you will be asked to continue taking apixaban for a certain number of weeks. If you are taking it to protect you from blood clots developing (such as if you have atrial fibrillation), you will be asked to continue to take it over a longer period of time.

  • If you take any medicines that you have bought without a prescription, check with a pharmacist that they are suitable to take with apixaban. This is because some medicines, such as aspirin and some anti-inflammatory painkillers, can interfere with it.

  • If you are due to have an operation or dental treatment, tell the person carrying out the treatment which medicines you are taking. This is because it may become necessary for you to stop taking apixaban for a day or so.

Can apixaban tablets cause problems?

Along with their useful effects, most medicines can cause unwanted side-effects although not everyone experiences them. The table below contains some of the most common ones associated with apixaban. The best place to find a full list of the side-effects which can be associated with your medicine, is from the manufacturer's printed information leaflet supplied with the medicine. Alternatively, you can find an example of a manufacturer's information leaflet in the reference section below. Speak with your doctor or pharmacist if any of the following continue or become troublesome.

Common apixaban side-effects

(Diese betreffen weniger als 1 von 10 Personen)

Was kann ich tun, wenn ich das erlebe?

Bleeding (such as nosebleeds, bleeding gums) or bruising

If this continues or becomes troublesome, let your doctor know

Anaemia (which could make you feel very tired)

Ihr Arzt wird dies überprüfen

Übelkeit (Nausea)

Try taking your doses with something to eat

Wichtig: if you experience any unusual bleeding, or bleeding that doesn't stop within ten minutes, speak with your doctor straightaway or go to your local accident and emergency department.

Wenn Sie andere Symptome bemerken, die Ihrer Meinung nach auf die Tabletten zurückzuführen sein könnten, sprechen Sie mit Ihrem Arzt oder Apotheker für weitere Ratschläge.

How to store apixaban

  • Bewahren Sie alle Medikamente außerhalb der Reichweite und Sicht von Kindern auf.

  • An einem kühlen, trockenen Ort aufbewahren, fern von direkter Hitze und Licht.

Wichtige Informationen über alle Medikamente

Wichtige Informationen über alle Medikamente

Nehmen Sie niemals mehr als die vorgeschriebene Dosis ein. Wenn Sie vermuten, dass Sie oder jemand anderes eine Überdosis dieses Medikaments eingenommen haben könnte, gehen Sie in die Notaufnahme Ihres örtlichen Krankenhauses. Nehmen Sie den Behälter mit, auch wenn er leer ist.

Dieses Medikament ist für Sie. Geben Sie es niemals an andere Personen weiter, auch wenn deren Zustand ähnlich erscheint wie Ihrer.

Bewahren Sie keine abgelaufenen oder unerwünschten Medikamente auf. Bringen Sie sie zu Ihrer örtlichen Apotheke, die sie für Sie entsorgt.

Wenn Sie Fragen zu diesem Medikament haben, fragen Sie Ihren Apotheker.

Berichten Sie Nebenwirkungen eines Medikaments oder Impfstoffs

Wenn Sie Nebenwirkungen bemerken, können Sie diese online über die Yellow Card Webseite.

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Unsicher beim Mischen von Medikamenten?

Überprüfen Sie mögliche Wechselwirkungen zwischen Medikamenten, Nahrungsergänzungsmitteln und Lebensmitteln, bevor Sie sie zusammen einnehmen.

Häufig gestellte Fragen

What is the difference between Apixaban and Warfarin?

Apixaban and warfarin both help prevent blood clots. However, people taking warfarin need regular blood tests to monitor clotting times and adjust the dose, as it can change frequently. Apixaban works differently, so these regular blood tests are not necessary.

How long will I need to take Apixaban for?

The duration of your Apixaban treatment depends on why you are taking it. It could be for a few weeks, for example after hip or knee surgery, or it might be for a longer period, such as if you have atrial fibrillation to protect against blood clots.

Does Apixaban cause tiredness?

Yes, anaemia is a common side-effect of Apixaban, affecting fewer than 1 in 10 people, and it can make you feel very tired. Your doctor will monitor you for this.

Can I take other medicines with Apixaban?

You should check with your doctor or a pharmacist before taking any other medicines, including those you can buy without a prescription, herbal remedies, or complementary medicines. Some, like aspirin and certain anti-inflammatory painkillers, can interfere with Apixaban.

What should I do if I cannot swallow the Apixaban tablet whole?

If you have difficulty swallowing the tablet whole, you can crush it and mix it with 30 ml (two tablespoons) of water or apple juice. Alternatively, you can mix it with some apple purée. Make sure to swallow the mixture immediately after preparing it.

Weiterführende Literatur und Referenzen

Über den AutorVollständige Biografie anzeigen

Autorenbild

Helen Allen, MPharm

Pharmacist, Medical Author

MPharm

Helen Allen qualified as a Pharmacist in 1979 and spent 3 years as the drug information leaflets' author for EMIS.

Über den Rezensenten

Autorenbild

Sid Dajani

Sultan Dajani qualifizierte sich 1994 an der London School of Pharmacy und wurde das jüngste gewählte Mitglied des Rates der Royal Pharmaceutical Society seit ihrer Gründung im Jahr 1842.

Artikelverlauf

Die Informationen auf dieser Seite wurden von qualifizierten Klinikern verfasst und begutachtet.

  • Nächste Überprüfung fällig: 25. Mär 2027
  • 27 Oct 2022 | Neueste Version

    Zuletzt aktualisiert von

    Michael Stewart, MRPharmS

    Begutachtet von

    Sid Dajani
  • 6 Nov 2013 | Ursprünglich veröffentlicht

    Verfasst von:

    Helen Allen, MPharm
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