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Calcipotriol für Psoriasis

Dovonex

Calcipotriol is usually applied once or twice each day. Your doctor will tell you which is right for you.

Do not use more than the maximum recommended amount of preparation.

Remember to wash your hands well after using calcipotriol. This will help to prevent accidentally getting it on other areas of your skin, which could cause irritation.

At a glance

  • Calcipotriol is a cream, gel, foam, or scalp solution used to treat plaque psoriasis.

  • It works by slowing down the overproduction of skin cells.

  • You must not use more than the maximum recommended amount each week.

  • Skin may become more sensitive to sunlight; avoid sunbeds and strong sun.

  • Common side-effects include burning, stinging, redness, itching, or irritation.

  • Wash your hands after use to prevent irritation on unaffected skin.

  • Do not use calcipotriol on your face as it can cause irritation.

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About calcipotriol

Art des Medikaments

A topical vitamin D analogue

Verwendet für

Plaque psoriasis in adults and in children aged over 6 years

Auch genannt

Calcipotriene (in US);
Dovonex®;
Combination brands: Dovobet®, Dalbecal®, Enstilar®, Wynzora® (calcipotriol with Betamethason)

Verfügbar als

Ointment, gel, foam and scalp solution

Calcipotriol is used to treat Plaque-Psoriasis - this is the most common type of psoriasis. It is a condition where red scaly patches called plaques develop on your skin. The most common areas affected are over your elbows and knees, the scalp, and the lower part of your back. The patches may vary in size from time to time and can be itchy. Treatment for psoriasis aims to clear the plaques as much as possible.

Psoriasis is caused by cells in the outer layer of your skin multiplying faster than normal. This causes the older and dead skin cells to build up on the surface of your skin, causing the scaly patches. Calcipotriol works by slowing this overproduction of skin cells which eases the inflamed, scaly areas. It is similar to vitamin D, which is a vitamin essential for healthy skin.

Sometimes calcipotriol is used in combination with a steroid medicine called Betamethason (as in a brand called Dovobet®). It is not recommended that a steroid be used long-term, so this combination is often used for around a month, followed by treatment with calcipotriol alone.

To make sure that this is the right treatment for you, before you start using calcipotriol it is important that your doctor knows:

  • Wenn Sie schwanger sind, versuchen, schwanger zu werden oder stillen.

  • If you have been told you have a form of psoriasis known as erythrodermic or pustular psoriasis. This is because more severe forms of psoriasis like these should only be treated by a skin specialist doctor.

  • If you have been told you have high calcium levels in your blood, or if your body has problems processing calcium.

  • If you are taking any other medicines or using any other skin preparations. This includes any medicines which are available to buy without a prescription, as well as herbal and complementary medicines.

  • Wenn Sie jemals eine allergische Reaktion auf ein Medikament hatten.

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  • Before you start the treatment, read the manufacturer's printed information leaflet from inside the pack. It will give you more information about applying calcipotriol and will provide you with a full list of the side-effects which you could experience from using it.

  • Your doctor will tell you how often to use the preparation you are given but as a guide:

    • Calcipotriol ointment is usually applied once or twice each day. If you have been told to use it twice a day, use it in the morning and in the evening.

    • Calcipotriol ointment which also contains betamethasone (brand name Dovobet® Ointment) should be applied only once a day. It is important that you do not use Dovobet® on areas of your skin which you think might be infected, and that you do not cover any treated areas with a bandage or dressing.

    • Calcipotriol scalp solution should be applied twice each day, in the morning and evening. The solution will quickly dry after it has been applied.

    • Calcipotriol with betamethasone gel (brand name Dovobet® Gel) should be applied once each day. For the best effect, leave it on during the day if you have applied it in the morning, or overnight if you have used it in the evening. It is suitable to be used on patches of psoriasis on your skin and on your scalp. It is important that you do not use Dovobet® on areas of your skin which you think might be infected, and that you do not cover any treated areas with a bandage or dressing.

    • Calcipotriol with betamethasone foam (brand name Enstilar®) should be applied once daily for four weeks. After that it can be used twice each week for long-term prevention. You should leave at least two days between applications.

  • The manufacturer's instructions state that you should not use more than a maximum amount of calcipotriol, as otherwise you may get too much calcium in your blood which can cause side-effects. Do not use more than:

    • 100 g of calcipotriol ointment per week for adults.

    • 75 g of calcipotriol ointment per week for children aged over 12 years.

    • 50 g of calcipotriol ointment per week for children aged between 6 and 12 years.

    • 60 ml of calcipotriol scalp solution per week for adults.

    • 15 g per day of Dovobet® Ointment or Gel for adults.

    • 15 g per day of Ensilar® cutaneous foam for adults

Wichtig: if you are using more than one preparation which contains calcipotriol, the total amount of all products you use should not be more than the amounts stated above.

  • Versuchen Sie, Ihre regelmäßigen Termine mit Ihrem Arzt einzuhalten. So kann Ihr Arzt Ihren Fortschritt überprüfen.

  • You should start to see an improvement in your skin within a week or so and this improvement should continue for several weeks before you feel the full benefit. Continue to apply the preparation regularly for as long as you have been recommended so that you get the full benefit.

  • If you are also using a moisturiser for your skin, use this first and then wait until it has soaked into your skin before you apply calcipotriol.

  • Calcipotriol can cause skin irritation. Because of this, you should not use it on your face.

  • Wash your hands well after using any calcipotriol preparation. This will help to prevent calcipotriol getting on to any areas of your skin which are unaffected by psoriasis, and causing irritation.

  • Your skin may become more sensitive to sunlight than normal while you are using calcipotriol. Try to avoid sitting out in the sun and do not use sunbeds.

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Along with their useful effects, most medicines can cause unwanted side-effects although not everyone experiences them. The table below contains some of the most common ones associated with calcipotriol. You will find a full list in the manufacturer's information leaflet supplied with the medicine. The unwanted effects often improve as your body adjusts to the new medicine but speak with your doctor or pharmacist if any of the following continue or become troublesome.

Very common calcipotriol side-effects (these affect more 1 in 10 people)

Was kann ich tun, wenn ich das erlebe?

A burning or stinging feeling

This should soon pass but if it continues or becomes severe, speak with your doctor

Common calcipotriol side-effects (these affect fewer than 1 in 10 people)

Was kann ich tun, wenn ich das erlebe?

Skin redness, itching, irritation, tingling, or dryness

These should soon pass but if any continue or become severe, speak with your doctor

Wichtig: there is a risk of fire when creams and ointments are absorbed by fabrics (such as clothing or bedsheets), making them flammable. A spark or flame can easily ignite the fabric. The risk is highest when large amounts of paraffin-based products are applied and absorb into fabrics. However there is also a risk when non-paraffin products are used. Be aware of this fire hazard when repeatedly using large amounts of any skin product. Do not smoke or go near naked flames.

Wenn Sie andere Symptome bemerken, die Ihrer Meinung nach auf die Vorbereitung zurückzuführen sind, sprechen Sie bitte mit Ihrem Arzt oder Apotheker für weitere Ratschläge.

  • Bewahren Sie alle Medikamente außerhalb der Reichweite und Sicht von Kindern auf.

  • An einem kühlen, trockenen Ort aufbewahren, fern von direkter Hitze und Licht.

Wichtige Informationen über alle Medikamente

Wenn Sie Medikamente kaufen, fragen Sie einen Apotheker, ob sie sicher mit Ihren anderen Medikamenten eingenommen werden können.

If you are having an operation or dental treatment, please tell the person carrying out the treatment which medicines you are taking.

Diese Zubereitung ist nur zur äußerlichen Anwendung bestimmt. Wenn jemand versehentlich etwas davon verschluckt, gehen Sie in die Notaufnahme Ihres örtlichen Krankenhauses. Nehmen Sie den Behälter mit, auch wenn er leer ist.

Dieses Medikament ist für Sie. Geben Sie es niemals an andere Personen weiter, auch wenn deren Zustand ähnlich erscheint wie Ihrer.

Bewahren Sie keine abgelaufenen oder unerwünschten Medikamente auf. Bringen Sie sie zu Ihrer örtlichen Apotheke, die sie für Sie entsorgt.

Wenn Sie Fragen zu diesem Medikament haben, fragen Sie Ihren Apotheker.

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Häufig gestellte Fragen

Can calcipotriol be used for all types of psoriasis?

Calcipotriol is specifically used to treat plaque psoriasis, which is the most common form. However, if you have more severe types such as erythrodermic or pustular psoriasis, these should only be treated by a skin specialist doctor, not with calcipotriol.

What is the role of vitamin D in calcipotriol treatment?

Calcipotriol is a 'vitamin D analogue', meaning it is similar to vitamin D. Vitamin D is essential for healthy skin, and calcipotriol works by mimicking its effects to slow down the overproduction of skin cells that causes psoriasis plaques.

Why is calcipotriol sometimes combined with betamethasone?

Sometimes calcipotriol is used in combination with betamethasone, which is a steroid medicine. This combination can be used for about a month, aiming to quickly reduce inflammation, before transitioning to calcipotriol alone, as steroids are not recommended for long-term use.

Is there a limit to how much calcipotriol I can use?

Yes, there is a maximum amount of calcipotriol you should use each week prescribed by the manufacturer. Exceeding this limit can lead to too much calcium in your blood, which can cause side-effects. For example, adults should not use more than 100g of calcipotriol ointment per week. If you are using more than one product containing calcipotriol, the total amount of all products must not exceed the weekly limits.

What should I do if I forget to apply my calcipotriol dose?

The article does not specify what to do if you miss a dose. However, generally it is important to follow your doctor's instructions for how often to use the preparation. If you are unsure, you should consult with your doctor or pharmacist.

Can I use calcipotriol on my face?

No, calcipotriol can cause skin irritation, so you should not use it on your face.

How long will it take to see improvements in my skin when using calcipotriol?

You should start to see an improvement in your skin within about a week. This improvement should continue for several weeks until you feel the full benefit. It's important to keep applying the preparation regularly as recommended to get the best results.

Are there any precautions I should take regarding sun exposure while using calcipotriol?

Yes, your skin may become more sensitive to sunlight while you are using calcipotriol. It's recommended to try and avoid sitting out in the sun and you should not use sunbeds.

Weiterführende Literatur und Referenzen

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About the authorView full bio

Author image

Michael Stewart, MRPharmS

Manager für die Überprüfung von Beipackzetteln – Auftragnehmer, Apotheker

BPharm (Hons), MRPharmS

Michael ist ein Gemeindapotheker, der in den Midlands und South Yorkshire praktiziert und über mehr als 20 Jahre Erfahrung in der Beratung zu Medikamenten und medizinischen Bedingungen verfügt. Er hat einen starken Hintergrund in der Gesundheitsausbildung, da er Schulungskurse für Apothekenteams und Mitarbeiter von Pflegeeinrichtungen, einschließlich Krankenschwestern, erstellt und durchgeführt hat. Er hat auch zu Apothekenbeiräten für das Management von geringfügigen Erkrankungen in der Gemeinschaft beigetragen.

About the reviewer

Author image

Sid Dajani

Sultan Dajani qualified at the London School of Pharmacy in 1994 and became the youngest elected member of the Royal Pharmaceutical Society council since its founding in 1842.

Artikelverlauf

Die Informationen auf dieser Seite wurden von qualifizierten Klinikern verfasst und begutachtet.

  • Nächste Überprüfung fällig: 21. Sept 2027
  • 20. Sept 2024 | Neueste Version

    Zuletzt aktualisiert von

    Michael Stewart, MRPharmS

    Begutachtet von

    Sid Dajani
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