Durchfallmittel
Begutachtet von Dr Colin Tidy, MRCGPZuletzt aktualisiert von Dr Toni Hazell, MRCGPZuletzt aktualisiert 26. März 2023
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Durchfallmedikamente (Medikamente zur Linderung der Durchfallsymptome) verringern die Häufigkeit, mit der Sie die Toilette aufsuchen müssen, wenn Sie akuten Durchfall haben. Das am häufigsten verwendete Medikament ist Loperamid. Sie können es in Ihrer örtlichen Apotheke kaufen oder auf Rezept von Ihrem Arzt erhalten. Die meisten Menschen müssen diese Medikamente nur wenige Tage lang einnehmen, und sie sind nicht bei jeder Durchfallerkrankung erforderlich. Kinder unter 12 Jahren sollten keine Durchfallmedikamente einnehmen, es sei denn, ihr Arzt hat es ihnen ausdrücklich empfohlen.
Auf einen Blick
Diarrhoea medicines reduce how often you need to go to the toilet.
Antimotility medicines like loperamide slow gut movement to make stools firmer.
These medicines are generally not advised for people under 12 years old.
Side-effects can include constipation, dizziness, or feeling sick.
Do not take these medicines if you have blood or mucus in your stools and a high temperature.
Fluid replacement is the most important treatment for diarrhoea.

Unsicher beim Mischen von Medikamenten?
Überprüfen Sie mögliche Wechselwirkungen zwischen Medikamenten, Nahrungsergänzungsmitteln und Lebensmitteln, bevor Sie sie zusammen einnehmen.
Was ist Durchfall medicine?
Durchfallmittel is used to reduce the number of trips that you need to make to the toilet when you have diarrhoea. Two main types of diarrhoea medicines are used to treat diarrhoea. These are called antimotility medicines and bulk-forming agents:
Antimotility medicines
This type of diarrhoea medicine is used to treat acute diarrhoea. They include:
Codeine phosphate.
Co-phenotrope.
Loperamide.
Kaolin and morphine mixture.
The most commonly used antimotility medicine is loperamide (Imodium®). Kaolin and morphine mixture is very rarely used to treat diarrhoea nowadays. Antimotility medicines are generally not advised for children under the age of 12 and is only available to buy over the counter for those aged 12 or over.
Flüssigkeitsersatz
It is important to remember that diarrhoea medicines are not the only treatments used for diarrhoea. The most important treatment is fluid replacement. See separate leaflets called Akuter Durchfall bei Kindern, und Durchfall.
The rest of this leaflet deals only with antimotility medicines when they are used to ease the symptoms of acute diarrhoea. For information on bulk-forming agents, see separate leaflet called Irritable Bowel Syndrome.
How do antimotility diarrhoea medicines work?
Antimotility medicines work by slowing down the movement of your gut, which reduces the speed at which the contents pass through. Food remains in your gut for longer and this allows more water to be absorbed back into your body. This results in firmer stools that are passed less often.
Antimotility medicines reduce the number of times you need to go to the toilet. This can be helpful in allowing you to continue your normal activities, or if you need to travel anywhere. However, there is no convincing evidence that they reduce the duration of the diarrhoea. Most cases of acute diarrhoea get better on their own in exactly the same amount of time, whether you take any medicines or not.
Which antimotility medicines are normally used to treat acute diarrhoea?
Loperamide is the most commonly used antimotility medicine for acute diarrhoea. It is thought to be the safest and most effective antimotility medicine. Co-phenotrope und Codein are used much less often than loperamide.
As discussed above, kaolin and morphine mixture is an older treatment for acute diarrhoea and is very rarely used nowadays.
When should I take an antimotility diarrhoea medicine?
For most adults and children older than 12 years, antimotility medicines are usually not necessary when they have a bout of diarrhoea. However, some people may wish to reduce the number of trips that they need to make to the toilet. For example, if you have to make an essential journey, taking antimotility medicines may help to make this possible.
Children should not be given antimotility medicines. This is because some children have had very serious side-effects after they have taken these medicines.
How should I take antimotility diarrhoea medicines?
The following directions are for adults only:
Loperamide - the adult dose of this is two capsules at first. This is followed by one capsule after each time you pass some diarrhoea, up to a maximum of eight capsules in 24 hours.
Co-phenotrope - the adult dose is four tablets at first. Six hours later, take two more tablets. After that, take two tablets every six hours.
Codeine phosphate - for adults, the usual dose is one 15 mg tablet, up to four times a day.
Wie lange dauert die Behandlung in der Regel?
Most people only need to take an antimotility medicine for a few days. In general, you should not take these medicines for longer than five days unless your doctor has told you to do so.
Where can I buy diarrhoea medicine?
You can buy loperamide and co-phenotrope from your local pharmacy. You can also obtain both of these medicines from your doctor, on prescription. Codeine phosphate is only available from your doctor, on a prescription.
You can only buy kaolin and morphine mixture from your local pharmacy, but quite a few pharmacies do not keep this medicine any more.
Antisecretory medicines are only available from your doctor, on prescription.
Diarrhoea medicine side-effects
The most commonly reported adverse effects of antimotility diarrhoea medicines are:
Excessive farting (breaking wind).
Drowsiness (If this happens, do not drive and do not use tools or machines).
Rare symptoms you may experience are:
Hautausschläge.
Juckende Haut.
Some children have very serious side-effects after they have taken these medicines - for example:
A condition where part of the gut dies (necrotising enterocolitis).
fühlen.
Depressed breathing.
Koma.
Some children have died after taking these medicines - this is very rare. However, this is why these medicines are not recommended for children.
For a full list of side-effects see the leaflet that comes with your medicine.
Who cannot take diarrhoea medicines?
You should not take diarrhoea medicine if:
You are younger than 12 years of age (unless prescribed by your doctor)
You have blood or mucus in the stools (faeces), and a hohe Temperatur (Fieber).
You have tummy (abdominal) distention.
You have inflammation of the gut (active ulcerative colitis).
You have inflammation of the gut caused by antibiotics (antibiotic-associated colitis).
What is acute diarrhoea?
Diarrhoea is the passing of frequent loose or liquid stools (faeces). When this change to the stools starts suddenly and lasts for less than two weeks, the condition is known as acute diarrhoea. If it lasts more than two weeks, it is called persistent diarrhoea. If it lasts more than four weeks it is called chronic diarrhoea. There are a number of causes of acute diarrhoea:
Infection of the gut is the common cause. This is called acute infectious diarrhoea. Many bacteria, viruses and other germs can cause diarrhoea. Sometimes the germs come from infected food (Lebensmittelvergiftung). Infected water is a cause in some countries. Sometimes it is just 'one of those germs going about'. Viruses are easily spread from one person to another by close contact, or when an infected person prepares food for others.
Other causes are uncommon and include side-effects from some medicines, Nahrungsmittelallergie und Angstzustände.
Gut disorders that cause chronic diarrhoea may be mistaken for acute diarrhoea when they first begin - for example, diarrhoea caused by Colitis ulcerosa.
Usually no treatment is required when you have acute diarrhoea, other than drinking plenty of fluids.
See the separate leaflets called Durchfall und Akuter Durchfall bei Kindern.

Unsicher beim Mischen von Medikamenten?
Überprüfen Sie mögliche Wechselwirkungen zwischen Medikamenten, Nahrungsergänzungsmitteln und Lebensmitteln, bevor Sie sie zusammen einnehmen.
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Häufig gestellte Fragen
Does taking diarrhoea medicine mean I can eat normally?
Diarrhoea medicine helps firm up stools and reduce the frequency of bowel movements, allowing for more normal activities. However, the most important treatment for diarrhoea is fluid replacement. The article does not suggest that taking these medicines alters dietary recommendations during a bout of diarrhoea.
What is the difference between acute, persistent, and chronic diarrhoea?
Acute diarrhoea starts suddenly and typically lasts for less than two weeks. If it continues for more than two weeks, it's referred to as persistent diarrhoea. Diarrhoea that lasts for over four weeks is classified as chronic diarrhoea.
Are antimotility medicines suitable for treating chronic or persistent diarrhoea?
The article specifically states that antimotility medicines are used to ease the symptoms of acute diarrhoea. It does not provide information on their use for persistent or chronic diarrhoea.
Can antimotility medicines treat the cause of my diarrhoea?
Antimotility medicines work by slowing down gut movement to reduce stool frequency and make stools firmer. They do not reduce the duration of diarrhoea, as most cases of acute diarrhoea resolve on their own, regardless of whether medicine is taken. They primarily manage symptoms rather than treating the underlying cause.
Weiterführende Literatur und Referenzen
- Durchfall und Erbrechen bei Kindern unter 5 Jahren; NICE Klinische Leitlinie (April 2009; aktualisiert Oktober 2022).
- Britisches Nationales Arzneimittelverzeichnis (BNF); NICE Evidenzdienste (nur in Großbritannien zugänglich)
- Durchfall - Beurteilung bei Erwachsenen; NICE CKS, November 2023 (nur für UK-Zugang)
- Boland A, Tunnard GJ, Bazaz R; Over-the-counter kaolin and morphine: two hazards in one. BMJ Case Rep. 2010;2010:bcr07.2009.2117. doi: 10.1136/bcr.07.2009.2117. Epub 2010 Mar 26.
Über den Autor

Jenny Whitehall
BSc (Hons), Diploma in Pharmacy Practice
Über den RezensentenVollständige Biografie anzeigen

Dr Colin Tidy, MRCGP
Allgemeinmediziner, Medizinischer Autor
MBBS, MRCGP, MRCP (Paediatrics), DCH
Dr. Colin Tidy ist ein NHS-Arzt mit Sitz in Oxfordshire.
Artikelverlauf
Die Informationen auf dieser Seite wurden von qualifizierten Klinikern verfasst und begutachtet.
Artikel auch verfügbar in Englisch, Deutsch, Spanisch, Französisch, Italienisch, Portugiesisch, Hindi, Hebräisch, Arabisch, und Schwedisch.
Nächste Überprüfung fällig: 24. März 2028
26. März 2023 | Neueste Version
20 Apr 2012 | Ursprünglich veröffentlicht
Verfasst von:
Jenny Whitehall

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