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Durchfallmittel

Durchfallmedikamente (Medikamente zur Linderung der Durchfallsymptome) verringern die Häufigkeit, mit der Sie die Toilette aufsuchen müssen, wenn Sie akuten Durchfall haben. Das am häufigsten verwendete Medikament ist Loperamid. Sie können es in Ihrer örtlichen Apotheke kaufen oder auf Rezept von Ihrem Arzt erhalten. Die meisten Menschen müssen diese Medikamente nur wenige Tage lang einnehmen, und sie sind nicht bei jeder Durchfallerkrankung erforderlich. Kinder unter 12 Jahren sollten keine Durchfallmedikamente einnehmen, es sei denn, ihr Arzt hat es ihnen ausdrücklich empfohlen.

At a glance

  • Diarrhoea medicines reduce how often you need to go to the toilet.

  • Antimotility medicines like loperamide work by slowing gut movement.

  • These medicines are generally not advised for children under 12 years.

  • Most acute diarrhoea gets better on its own without medicine.

  • Possible side-effects include constipation, dizziness, and headaches.

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Was ist Durchfall medicine?

Durchfallmittel is used to reduce the number of trips that you need to make to the toilet when you have diarrhoea. Two main types of diarrhoea medicines are used to treat diarrhoea. These are called antimotility medicines and bulk-forming agents:

Antimotility medicines

This type of diarrhoea medicine is used to treat acute diarrhoea. They include:

  • Codeine phosphate.

  • Co-phenotrope.

  • Loperamide.

  • Kaolin and morphine mixture.

The most commonly used antimotility medicine is loperamide (Imodium®). Kaolin and morphine mixture is very rarely used to treat diarrhoea nowadays. Antimotility medicines are generally not advised for children under the age of 12 and is only available to buy over the counter for those aged 12 or over.

Flüssigkeitsersatz

It is important to remember that diarrhoea medicines are not the only treatments used for diarrhoea. The most important treatment is fluid replacement. See separate leaflets called Akuter Durchfall bei Kindern, and Durchfall.

The rest of this leaflet deals only with antimotility medicines when they are used to ease the symptoms of acute diarrhoea. For information on bulk-forming agents, see separate leaflet called Irritable Bowel Syndrome.

Antimotility medicines work by slowing down the movement of your gut, which reduces the speed at which the contents pass through. Food remains in your gut for longer and this allows more water to be absorbed back into your body. This results in firmer stools that are passed less often.

Antimotility medicines reduce the number of times you need to go to the toilet. This can be helpful in allowing you to continue your normal activities, or if you need to travel anywhere. However, there is no convincing evidence that they reduce the duration of the diarrhoea. Most cases of acute diarrhoea get better on their own in exactly the same amount of time, whether you take any medicines or not.

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Loperamide is the most commonly used antimotility medicine for acute diarrhoea. It is thought to be the safest and most effective antimotility medicine. Co-phenotrope und Codein are used much less often than loperamide.

As discussed above, kaolin and morphine mixture is an older treatment for acute diarrhoea and is very rarely used nowadays.

For most adults and children older than 12 years, antimotility medicines are usually not necessary when they have a bout of diarrhoea. However, some people may wish to reduce the number of trips that they need to make to the toilet. For example, if you have to make an essential journey, taking antimotility medicines may help to make this possible.

Children should not be given antimotility medicines. This is because some children have had very serious side-effects after they have taken these medicines.

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The following directions are for adults only:

Loperamide - the adult dose of this is two capsules at first. This is followed by one capsule after each time you pass some diarrhoea, up to a maximum of eight capsules in 24 hours.

Co-phenotrope - the adult dose is four tablets at first. Six hours later, take two more tablets. After that, take two tablets every six hours.

Codeine phosphate - for adults, the usual dose is one 15 mg tablet, up to four times a day.

Wie lange dauert die Behandlung in der Regel?

Most people only need to take an antimotility medicine for a few days. In general, you should not take these medicines for longer than five days unless your doctor has told you to do so.

You can buy loperamide and co-phenotrope from your local pharmacy. You can also obtain both of these medicines from your doctor, on prescription. Codeine phosphate is only available from your doctor, on a prescription.

You can only buy kaolin and morphine mixture from your local pharmacy, but quite a few pharmacies do not keep this medicine any more.

Antisecretory medicines are only available from your doctor, on prescription.

The most commonly reported adverse effects of antimotility diarrhoea medicines are:

Rare symptoms you may experience are:

Some children have very serious side-effects after they have taken these medicines - for example:

  • A condition where part of the gut dies (necrotising enterocolitis).

  • fühlen.

  • Depressed breathing.

  • Koma.

Some children have died after taking these medicines - this is very rare. However, this is why these medicines are not recommended for children.

For a full list of side-effects see the leaflet that comes with your medicine.

You should not take diarrhoea medicine if:

Diarrhoea is the passing of frequent loose or liquid stools (faeces). When this change to the stools starts suddenly and lasts for less than two weeks, the condition is known as acute diarrhoea. If it lasts more than two weeks, it is called persistent diarrhoea. If it lasts more than four weeks it is called chronic diarrhoea. There are a number of causes of acute diarrhoea:

  • Infection of the gut is the common cause. This is called acute infectious diarrhoea. Many bacteria, viruses and other germs can cause diarrhoea. Sometimes the germs come from infected food (Lebensmittelvergiftung). Infected water is a cause in some countries. Sometimes it is just 'one of those germs going about'. Viruses are easily spread from one person to another by close contact, or when an infected person prepares food for others.

  • Other causes are uncommon and include side-effects from some medicines, Nahrungsmittelallergie und Angstzustände.

  • Gut disorders that cause chronic diarrhoea may be mistaken for acute diarrhoea when they first begin - for example, diarrhoea caused by Colitis ulcerosa.

Usually no treatment is required when you have acute diarrhoea, other than drinking plenty of fluids.

See the separate leaflets called Durchfall und Akuter Durchfall bei Kindern.

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Häufig gestellte Fragen

Can I give these medicines to my children?

Antimotility medicines are generally not advised for children under the age of 12. Only those aged 12 or over can buy loperamide over the counter. Some children have experienced very serious side-effects, including a condition where part of the gut dies, confusion, depressed breathing, and coma, and in rare cases, even death, which is why these medicines are not recommended for children.

How long do antimotility medicines take to work?

The article details the dosage instructions for various antimotility medicines, including an initial dose, and subsequent doses after passing diarrhoea or at regular intervals. However, it does not specify how quickly the medicines start to reduce the frequency of bowel movements. It states that they work by slowing gut movement to allow more water to be absorbed, which results in firmer stools passed less often.

What's the difference between fluid replacement and diarrhoea medicine?

Fluid replacement is considered the most important treatment for diarrhoea. Diarrhoea medicines, specifically antimotility medicines, work by slowing down your gut to reduce how often you need to go to the toilet and make stools firmer. They do not shorten how long the diarrhoea lasts, whereas fluid replacement addresses the loss of liquids from your body.

If these medicines reduce the number of toilet trips, do they also make my diarrhoea go away faster?

Antimotility medicines are helpful for reducing the number of times you need to go to the toilet, which can be convenient for continuing normal activities or when travelling. However, there is no convincing evidence that they reduce the duration of the diarrhoea. Most cases of acute diarrhoea resolve on their own in the same amount of time, regardless of whether you take these medicines.

Can I use these medicines if I have blood in my stools?

No, you should not take diarrhoea medicine if you have blood or mucus in your stools and a high temperature (fever).

What should I do if I experience side-effects from these medicines?

If you think you have had a side-effect to one of your medicines, you can report this using the Yellow Card Scheme online at www.mhra.gov.uk/yellowcard. You will need to provide basic information about the side-effect, the medicine you think caused it, the person affected, and your contact details.

Are there other types of diarrhoea medicine mentioned in the article?

Yes, the article mentions two main types of diarrhoea medicine: antimotility medicines and bulk-forming agents. It also briefly refers to antisecretory medicines. This leaflet specifically deals with antimotility medicines, and points to separate leaflets for information on bulk-forming agents and fluid replacement.

Weiterführende Literatur und Referenzen

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About the author

Author image

Jenny Whitehall

BSc (Hons), Diploma in Pharmacy Practice

About the reviewerView full bio

Author image

Dr Colin Tidy, MRCGP

Allgemeinmediziner, Medizinischer Autor

MBBS, MRCGP, MRCP (Paediatrics), DCH

Dr. Colin Tidy ist ein NHS-Arzt mit Sitz in Oxfordshire.

Artikelverlauf

Die Informationen auf dieser Seite wurden von qualifizierten Klinikern verfasst und begutachtet.

  • Nächste Überprüfung fällig: 24. März 2028
  • 26. März 2023 | Neueste Version

    Zuletzt aktualisiert von

    Dr Toni Hazell, MRCGP

    Begutachtet von

    Dr Colin Tidy, MRCGP
  • 20 Apr 2012 | Ursprünglich veröffentlicht

    Verfasst von:

    Jenny Whitehall
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