Zum Hauptinhalt springen

Can I take Amlodipine and Aspirin 300 together?

Drug interaction guide

Taking aspirin with amlodipine may slightly increase the risk of stomach irritation or bleeding, and high doses of aspirin (like 300mg) can sometimes make blood pressure medication slightly less effective.

Lesen Sie unten weiter

Why this happens

Aspirin belongs to a group of medicines called NSAIDs. These can cause the body to hold onto salt and water, which works against amlodipine's job of lowering blood pressure. Additionally, both medicines can affect blood flow and the lining of the stomach.

It is generally safe to take these together occasionally, but you should monitor your blood pressure regularly. If you need to take 300mg of aspirin frequently, speak to your GP or pharmacist, as they may prefer you to use a different painkiller like paracetamol which does not affect blood pressure. Seek medical advice if you notice any unusual bruising or dark, tarry stools.

Lesen Sie unten weiter

Asthma

Do not take aspirin if you have a history of asthma triggered by aspirin or other non-steroidal anti-inflammatory drugs (NSAIDs), as it can cause a severe, life-threatening asthma attack.

Stomach ulcers or bleeding disorders

Avoid aspirin if you have an active stomach ulcer or a history of bleeding problems, as it significantly increases the risk of serious internal bleeding.

Grapefruit juice

Grapefruit juice can increase the amount of amlodipine in your body and may cause your blood pressure to drop too low. It is best to avoid drinking large amounts of grapefruit juice while taking this medicine.

Alkohol

Drinking alcohol while taking aspirin can increase the risk of irritation and bleeding in your stomach. It is best to limit alcohol intake or avoid it if you have a sensitive stomach.

Lesen Sie unten weiter

Taking multiple medicines? Our Medicines Interaction Checker helps you check whether your prescriptions, over-the-counter medicines, and supplements are safe to take together. Simply search for your medicines to see potential interactions and what to do about them.

Haftungsausschluss

This information is for general educational purposes only and should not be relied upon as a substitute for professional medical advice. Always consult your GP, pharmacist, or another qualified healthcare professional before making decisions about your medications. Individual circumstances may vary, and only a healthcare professional who knows your medical history can provide personalised guidance.

Lesen Sie unten weiter

Artikel Geschichte

Die Informationen auf dieser Seite wurden von qualifizierten Klinikern verfasst und von Fachleuten geprüft.

  • 25 Jan 2026 | Ursprünglich veröffentlicht
Grippe-Tauglichkeitsprüfung

Fragen, teilen, verbinden.

Stöbern Sie in Diskussionen, stellen Sie Fragen, und tauschen Sie Erfahrungen zu Hunderten von Gesundheitsthemen aus.

Symptom-Prüfer

Fühlen Sie sich unwohl?

Beurteilen Sie Ihre Symptome online und kostenlos

Melden Sie sich für den Patienten-Newsletter an

Ihre wöchentliche Dosis klarer, vertrauenswürdiger Gesundheitsratschläge – geschrieben, damit Sie sich informiert, sicher und unter Kontrolle fühlen.

Bitte geben Sie eine gültige E-Mail-Adresse ein.

Mit Ihrer Anmeldung akzeptieren Sie unsere Datenschutzerklärung. Sie können sich jederzeit abmelden. Wir verkaufen Ihre Daten niemals weiter.