Kann ich Traubensilberkerze und Johanniskraut zusammen einnehmen?

Warum das passiert

Both supplements are processed by the liver. St John's wort is a potent inducer of liver enzymes (specifically CYP3A4), which can speed up the breakdown of other substances. Furthermore, both herbs have been independently linked to rare cases of hepatotoxicity (liver damage), and taking them together may theoretically increase this risk.

You should consult your doctor or a pharmacist before taking these two supplements together. If you do use them, watch for signs of liver trouble, such as yellowing of the eyes or skin (jaundice), dark urine, severe stomach pain, or unusual tiredness. It is also important to tell your doctor if you are taking any other prescribed medications, as St John's wort interacts with many common drugs.

Schwangerschaft

Verwenden Sie Schwarzer Cohosh während der Schwangerschaft nicht. Es kann Wehen auslösen und das Risiko einer Fehlgeburt oder Frühgeburt erhöhen.

Lebererkrankung

Schwarzer Cohosh wurde mit seltenen, aber schweren Fällen von Leberversagen in Verbindung gebracht. Sie müssen die Einnahme sofort beenden und umgehend einen Arzt aufsuchen, wenn Sie Gelbfärbung der Haut oder Augen, dunklen Urin oder starke Bauchschmerzen entwickeln.

Hormonabhängige Erkrankungen (z. B. Brustkrebs)

Da Traubensilberkerze wie das Hormon Östrogen wirken kann, sollten Sie sie ohne ärztliche Fachberatung nicht verwenden, wenn Sie eine Vorgeschichte von Brustkrebs, Gebärmutterkrebs oder Endometriose haben.

Depression and Mental Health

Like other antidepressants, St John's wort may increase the risk of suicidal thoughts or self-harm, particularly when first starting treatment. Seek immediate medical help if your mood worsens.

Drug Interactions

St John's wort significantly reduces the effectiveness of many essential medicines, including the contraceptive pill, blood thinners (warfarin), epilepsy medications, and organ transplant drugs. Do not start it without a pharmacist checking your current medications.

Serotonin-Syndrom

Taking St John's wort with other antidepressants or triptans (for migraine) can cause serotonin syndrome, a potentially life-threatening condition involving high fever, agitation, and muscle rigidity.

Photosensitivity

St John's wort can make your skin significantly more sensitive to sunlight, leading to severe sunburn or skin reactions even with limited exposure.

Alkohol

Black cohosh has been linked to rare but serious cases of liver damage. Because alcohol also puts strain on the liver, it is advisable to limit or avoid alcohol consumption while taking this supplement to reduce the risk of liver toxicity. St John's wort can increase the sedative effects of alcohol, making you feel more drowsy or dizzy than usual. It is best to limit or avoid alcohol while taking this herbal remedy.

Koffein

St John's wort may increase sensitivity to caffeine. This can lead to increased feelings of anxiety, jitteriness, or a racing heart.

Foods high in Tyramine (e.g., aged cheeses, cured meats, fermented products)

Although the risk is lower than with older prescription antidepressants, St John's wort has some mild MAOI-like activity. Consuming very large amounts of tyramine-rich foods could potentially lead to a rise in blood pressure.

Taking multiple medicines? Our Wechselwirkungs-Checker für Medikamente helps you check whether your prescriptions, over-the-counter medicines, and supplements are safe to take together. Simply search for your medicines to see potential interactions and what to do about them.

Haftungsausschluss

Diese Informationen dienen nur allgemeinen Bildungszwecken und sollten nicht als Ersatz für professionelle medizinische Beratung herangezogen werden. Konsultieren Sie immer Ihren Hausarzt, Apotheker oder einen anderen qualifizierten Gesundheitsfachmann, bevor Sie Entscheidungen über Ihre Medikamente treffen. Individuelle Umstände können variieren, und nur ein Gesundheitsfachmann, der Ihre Krankengeschichte kennt, kann personalisierte Beratung bieten.