Can I take Vitamin B2 and Vitamin D together?
Drug interaction guide
Originally published 25 Jan 2026
Meets Patient’s editorial guidelines
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There is no known negative interaction between vitamin B2 (riboflavin) and vitamin D. In fact, they are often taken together in multivitamin supplements.
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Why this happens
Vitamin B2 and vitamin D are processed by the body through different pathways. Vitamin B2 is water-soluble and primarily excreted through urine, while vitamin D is fat-soluble and stored in the body's fatty tissues and liver. They do not compete for absorption or interfere with how the other works.
What you should do
Back to contentsIt is safe to take vitamin B2 and vitamin D together. Always follow the dosage instructions on the product packaging or those provided by your healthcare professional. Taking vitamin D with a meal containing some fat can help your body absorb it better.
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Important precautions
Back to contentsHypercalcaemia (high blood calcium)
Do not take vitamin D if you have high levels of calcium in your blood or urine, as it can lead to serious kidney damage and heart rhythm problems.
Food and drink warnings
Back to contentsAlcohol
It is best to avoid or strictly limit alcohol when taking Vitamin B2. Alcohol can interfere with the way your body absorbs this vitamin from the digestive tract, making the supplement less effective.
High-fat meals
Vitamin D is fat-soluble. It is best absorbed when taken with a meal that contains some fat (such as eggs, avocado, nuts, or dairy). Taking it on an empty stomach may reduce how much your body absorbs.
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Using other medicines
Back to contentsTaking multiple medicines? Our Medicines Interaction Checker helps you check whether your prescriptions, over-the-counter medicines, and supplements are safe to take together. Simply search for your medicines to see potential interactions and what to do about them.
Disclaimer
This information is for general educational purposes only and should not be relied upon as a substitute for professional medical advice. Always consult your GP, pharmacist, or another qualified healthcare professional before making decisions about your medications. Individual circumstances may vary, and only a healthcare professional who knows your medical history can provide personalised guidance.
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Treatment and medication
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There is no evidence of a direct harmful interaction between atorvastatin and turkey tail mushroom (Trametes versicolor). However, turkey tail may have a mild effect on how the liver processes certain medications, and it may also have its own subtle cholesterol-lowering properties.
Treatment and medication
Can I take Sildenafil and Atorvastatin together?
There is no known interaction between sildenafil (the active ingredient in Viagra) and atorvastatin (a cholesterol-lowering medicine). It is generally considered safe to take these two medications together.
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Article history
The information on this page is written and peer reviewed by qualified clinicians.
25 Jan 2026 | Originally published
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