Can I take Levothyroxine and Prednisolone together?
Drug interaction guide
Originally published 25 Jan 2026
Erfüllt die Anforderungen des Patienten redaktionelle Richtlinien
- HerunterladenHerunterladen
- Teilen Sie
- Sprache
- Diskussion
Taking prednisolone may change how much levothyroxine your body needs. You might find that your thyroid levels fluctuate, potentially leading to symptoms of an overactive or underactive thyroid while you are on the steroid treatment.
In diesem Artikel:
Lesen Sie unten weiter
Why this happens
Prednisolone (a corticosteroid) can affect how your body processes thyroid hormones. It can slightly reduce the conversion of the inactive hormone (T4) into the active form (T3) and may also affect the levels of proteins in your blood that carry the thyroid hormone around. Additionally, if you are taking levothyroxine for an underactive thyroid, the underlying condition itself can change how quickly your body clears prednisolone from your system.
What you should do
You should inform your doctor that you are taking both medications. They may want to perform a blood test to check your thyroid levels (TSH) shortly after you start or stop taking prednisolone. Do not change your dose of either medication without consulting your healthcare provider. If you feel unusually tired, cold, or notice a racing heart and tremors, let your doctor know.
Lesen Sie unten weiter
Using other medicines
Taking multiple medicines? Our Medicines Interaction Checker helps you check whether your prescriptions, over-the-counter medicines, and supplements are safe to take together. Simply search for your medicines to see potential interactions and what to do about them.
Haftungsausschluss
This information is for general educational purposes only and should not be relied upon as a substitute for professional medical advice. Always consult your GP, pharmacist, or another qualified healthcare professional before making decisions about your medications. Individual circumstances may vary, and only a healthcare professional who knows your medical history can provide personalised guidance.
Patient picks for Drug interactions

Behandlung und Medikamente
Can I take Hydroxycarbamide and Hydroxychloroquine together?
Both hydroxycarbamide and hydroxychloroquine can lower your blood cell counts. Taking them together may increase the risk of developing serious infections, anaemia (low red blood cells), or bruising and bleeding problems. There is also a small risk that both medications could affect your heart rhythm or increase the risk of skin reactions.

Behandlung und Medikamente
Can I take Esomeprazole and Vitamin c together?
Esomeprazole may slightly reduce how much Vitamin C your body absorbs, but this is generally not a cause for concern for most people.
Lesen Sie unten weiter
Artikel Geschichte
Die Informationen auf dieser Seite wurden von qualifizierten Klinikern verfasst und von Fachleuten geprüft.
25 Jan 2026 | Ursprünglich veröffentlicht

Fragen, teilen, verbinden.
Stöbern Sie in Diskussionen, stellen Sie Fragen, und tauschen Sie Erfahrungen zu Hunderten von Gesundheitsthemen aus.

Fühlen Sie sich unwohl?
Beurteilen Sie Ihre Symptome online und kostenlos
Melden Sie sich für den Patienten-Newsletter an
Ihre wöchentliche Dosis klarer, vertrauenswürdiger Gesundheitsratschläge – geschrieben, damit Sie sich informiert, sicher und unter Kontrolle fühlen.
Mit Ihrer Anmeldung akzeptieren Sie unsere Datenschutzerklärung. Sie können sich jederzeit abmelden. Wir verkaufen Ihre Daten niemals weiter.