Kann ich Mirtazapin und Sertralin zusammen einnehmen?

You should only take Mirtazapin und Sertralin together if they have been specifically prescribed by a specialist who is monitoring you closely.

Taking them together increases your risk of serotonin syndrome.

Warum das passiert

Both mirtazapine and sertraline work by increasing the levels of serotonin in the brain. When used together, their effects add up, which can lead to serotonin levels becoming dangerously high.

You may be experiencing an interaction between mirtazapine and sertraline if:

• You feel agitated, restless, or unusually anxious.

• You experience confusion or changes in mental state.

• You notice tremors, muscle twitching, or shaking.

• You have excessive sweating, flushing, or fever.

• You develop a fast or irregular heartbeat.

• You experience severe drowsiness or dizziness.

• Symptoms appear soon after starting, increasing, or combining the medicines.

Wenn Sie eines der oben genannten Symptome haben, sollten Sie:

• Contact your GP or pharmacist immediately for advice.

• Seek urgent medical help if symptoms are severe or include high fever, confusion, or a fast heartbeat.

• Do not stop taking mirtazapine or sertraline suddenly unless advised by a healthcare professional.

• Avoid alcohol and other medicines that can affect mood or cause drowsiness unless approved.

• Informieren Sie Ihren Gesundheitsdienstleister über alle anderen Medikamente und Nahrungsergänzungsmittel, die Sie einnehmen.

Serotonin-Syndrom

Taking these two medicines together significantly increases the risk of serotonin syndrome, a potentially life-threatening condition. Seek immediate medical help if you experience high fever, agitation, confusion, or muscle twitching.

Suicidal thoughts and worsening of depression

These medicines can cause an increase in suicidal thoughts or self-harm, particularly in the first few weeks of treatment or when the dose is changed. Patients under 25 are at higher risk.

Agranulozytose (niedrige Anzahl weißer Blutkörperchen)

Mirtazapine can rarely cause a serious drop in white blood cells. You must contact your doctor immediately if you develop a fever, sore throat, mouth ulcers, or any other signs of infection.

Blutungsstörungen

Sertralin kann Ihr Blutungsrisiko erhöhen, insbesondere im Magenbereich. Seien Sie vorsichtig bei der Einnahme von blutverdünnenden Medikamenten (wie Warfarin) oder entzündungshemmenden Schmerzmitteln (wie Ibuprofen oder Aspirin), da dies das Risiko schwerer Blutungen erheblich erhöht.

Alkohol

You should avoid or strictly limit alcohol while taking these medicines. Both mirtazapine and sertraline can increase the sedative effects of alcohol, making you feel more drowsy, dizzy, or uncoordinated. Mirtazapine, in particular, is very sedating.

Grapefruitsaft

Avoid drinking large amounts of grapefruit juice. It can increase the level of sertraline in your blood, which may increase the risk of side effects. One small glass is usually fine, but it is safest to avoid it.

Koffein (Kaffee, Tee, Energydrinks)

Mirtazapine is often taken at night because it helps with sleep. Consuming caffeine can counteract this effect and may increase feelings of restlessness or anxiety, which the medicine is intended to treat.

Taking multiple medicines? Our Wechselwirkungs-Checker für Medikamente helps you check whether your prescriptions, over-the-counter medicines, and supplements are safe to take together. Simply search for your medicines to see potential interactions and what to do about them.

Haftungsausschluss

Diese Informationen dienen nur allgemeinen Bildungszwecken und sollten nicht als Ersatz für professionelle medizinische Beratung herangezogen werden. Konsultieren Sie immer Ihren Hausarzt, Apotheker oder einen anderen qualifizierten Gesundheitsfachmann, bevor Sie Entscheidungen über Ihre Medikamente treffen. Individuelle Umstände können variieren, und nur ein Gesundheitsfachmann, der Ihre Krankengeschichte kennt, kann personalisierte Beratung bieten.