Adefovir für Hepatitis B

About adefovir

Hepatitis means inflammation of the liver. Some viruses can cause hepatitis. Hepatitis B is a virus which is carried in your bloodstream to your liver, where it can affect and damage your liver. Following infection with hepatitis B, a few people develop a persistent infection called chronic hepatitis B.

People with chronic hepatitis B usually need treatment to stop or to reduce the activity of the virus. This limits damage to the liver, which is a complication of the infection. One of the types of treatment currently given is an antiviral medicine. Antiviral medicines like adefovir work by stopping the hepatitis B virus from multiplying (replicating); this reduces the amount of the virus in your body.

A doctor who is a liver specialist will usually start the treatment for you. Treatment for chronic hepatitis B usually continues for several years, but can be lifelong. It can include more than one antiviral medicine.

Some medicines are not suitable for people with certain conditions, and sometimes a medicine can only be used if extra care is taken. For these reasons, before you start taking adefovir it is important that your doctor knows:

• Wenn Sie schwanger sind, versuchen, ein Baby zu bekommen, oder stillen.

• Wenn Sie ein Problem mit der Funktionsweise Ihrer Nieren haben.

• Wenn Sie andere Medikamente einnehmen. Dazu gehören alle Medikamente, die Sie einnehmen und die ohne Rezept erhältlich sind, sowie pflanzliche und ergänzende Medikamente.

• Wenn Sie jemals eine allergische Reaktion auf ein Medikament hatten.

• Before you start the treatment, read the manufacturer's printed information leaflet from inside your pack. It will give you more information about adefovir, and it will also provide you with a full list of the side-effects which you could experience from taking it.

• Take adefovir exactly as your doctor tells you to. The usual dose is one 10 mg tablet daily. You can take the tablet either with or without food.

• Try to take your doses at the same time of day each day, as this will help you to remember to take adefovir regularly.

• If you are ever sick within one hour of taking a tablet, you should take a second tablet. This is because your body will not have absorbed a sufficient amount of the medicine. If, however, you are sick and it is more than one hour after taking a tablet, you do not need to take a second dose, as your body will have already absorbed the full dose.

• If you forget to take a dose at your usual time, take it as soon as you remember. However, if you do not remember until the following day, leave out the missed dose. Do not take two doses together to make up for a forgotten dose.
  

• Vereinbaren Sie regelmäßig Termine bei Ihrem Arzt. So kann Ihr Fortschritt überwacht werden. Gelegentlich sind Blutuntersuchungen erforderlich.

• It is important that you continue to take adefovir regularly. Treatment for hepatitis B can be long-term. Continue to take the tablets, even if you feel well. This is to keep your liver healthy.

• Treatment with adefovir does not stop you from passing the infection on to others through sexual contact, sharing needles to inject drugs, or from mother to baby. A vaccine is available which protects against hepatitis B and can be offered to your sexual and household contacts who are at risk of being infected. Do not have sex with anyone (especially any sex without using a condom) until they have been fully immunised and have had their blood checked to see that the immunisation has worked.

• Die meisten Menschen mit chronischer Hepatitis B werden geraten, eine normale, gesunde und ausgewogene Ernährung zu sich zu nehmen. Es ist jedoch wahrscheinlich, dass Ihnen geraten wird, keinen Alkohol zu trinken. Alkohol erhöht das Risiko und die Geschwindigkeit, mit der sich Leberschäden entwickeln.

• Medicines similar to adefovir have been associated with a serious side-effect in a few people. This is known as lactic acidosis. It is a problem where there is too much lactic acid in the blood. The symptoms associated with it are listed in the next section 'Can adefovir cause problems?'. Although this has occurred in only a very few people, you must let your doctor know sofort if you develop the symptoms listed below.

• You must avoid getting pregnant while you are taking adefovir. Make sure you have discussed with your doctor which types of contraception are suitable for you.

• If you buy any medicines, supplements or herbal remedies 'over the counter', check with a pharmacist that they are suitable to take with adefovir and your other medicines.

• Wenn Sie sich einer Operation oder Zahnbehandlung unterziehen, informieren Sie die Person, die die Behandlung durchführt, welche Medikamente Sie einnehmen.

Along with their useful effects, most medicines can cause unwanted side-effects although not everyone experiences them. The table below contains some of the more common ones associated with adefovir. The best place to find a full list of the side-effects which can be associated with your medicine, is from the manufacturer's printed information leaflet supplied with the medicine. Alternatively, you can find an example of a manufacturer's information leaflet in the reference section below. Speak with your doctor or pharmacist if any of the following continue or become troublesome.

Your doctor will discuss with you the possibility of this medicine causing a problem called laktazidose. Let your doctor know straightaway if you develop the following symptoms:

• Übelkeit (Nausea) oder Erbrechen, Bauchschmerzen, Appetitlosigkeit, Gewichtsverlust, Schwäche oder Schwindelgefühl sowie schnelle oder keuchende Atmung.

Wenn Sie andere Symptome bemerken, die Ihrer Meinung nach auf die Tabletten zurückzuführen sein könnten, sprechen Sie mit Ihrem Arzt oder Apotheker für weitere Ratschläge.

• Bewahren Sie alle Medikamente außerhalb der Reichweite und Sicht von Kindern auf.

• An einem kühlen, trockenen Ort aufbewahren, fern von direkter Hitze und Licht.