Can I take Lixiana and Paracetamol together?
Drug interaction guide
Originally published 25 Jan 2026
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There is no known interaction between Lixiana (edoxaban) and paracetamol. It is generally considered the safest painkiller to take while on this type of medication.
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Why this happens
Lixiana is an anticoagulant (blood thinner) that works by blocking a specific clotting factor. Paracetamol works on the central nervous system to relieve pain and does not affect blood clotting or the way Lixiana is processed by the liver or kidneys.
What you should do
You can safely take paracetamol while taking Lixiana. However, you should avoid anti-inflammatory painkillers like ibuprofen (Nurofen) or aspirin unless specifically prescribed by your doctor, as these can increase your risk of bleeding.
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Using other medicines
Taking multiple medicines? Our Medicines Interaction Checker helps you check whether your prescriptions, over-the-counter medicines, and supplements are safe to take together. Simply search for your medicines to see potential interactions and what to do about them.
Haftungsausschluss
This information is for general educational purposes only and should not be relied upon as a substitute for professional medical advice. Always consult your GP, pharmacist, or another qualified healthcare professional before making decisions about your medications. Individual circumstances may vary, and only a healthcare professional who knows your medical history can provide personalised guidance.
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Artikel Geschichte
Die Informationen auf dieser Seite wurden von qualifizierten Klinikern verfasst und von Fachleuten geprüft.
25 Jan 2026 | Ursprünglich veröffentlicht
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