
Antibiotikaresistenz: eine versteckte Gesundheitskrise
Begutachtet von Dr Colin Tidy, MRCGPZuletzt aktualisiert von Victoria RawLast updated 20 Mar 2026
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If you have a bacterial infection, your doctor may prescribe antibiotics. However, unnecessary use of antibiotics can weaken their effectiveness, leading to antibiotic resistance and making future infections harder to treat.
Doctors and other appropriately qualified health professionals will only prescribe antibiotics where there is a critical need.
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What is antibiotic resistance?
Antibiotika are medicines designed to treat or prevent bacterial infections. They do this by destroying bacteria, or stopping them from reproducing.
According to the World Health Organization (WHO), the rise of antibiotic resistance is a global health emergency.
Sakib Mohammed, Pharmacist and Advanced Clinical Practitioner, Click2Pharmacy, Oldham, England explains that Antibiotikaresistenz happens when bacteria adapt to survive medicines meant to kill them, making infections tougher to fight.
For this reason, healthcare professionals are limiting antibiotic use for minor illnesses. They are no longer commonly prescribed to people with chest infections, Halsschmerzen, or children with ear infections.
What causes antibiotic resistance?
Zurück zum InhaltAntibiotics only work against bacterial infections. They don't work against viral or fungal infections. However, antibiotics are becoming less effective against the infections they're meant to treat.
There are several reasons for this.
Overuse and misuse
The more you use antibiotics, the more you'll become resistant to them. This is why it's important to avoid taking them unnecessarily - especially for viral infections.
Overusing antibiotics for minor infections harms their chance of working against more serious conditions.
Skipping doses or stopping antibiotics early can also leave behind resistant bacteria, which can multiply and spread.
Mohammed says: "Not finishing a prescription gives bacteria more chances to survive and adapt. Bacteria also naturally mutate. Those with mutations that resist antibiotics multiply, making infections harder to treat over time."
Superbugs
Overuse of antibiotics has resulted in superbugs - bacterial strains resistant to antibiotic treatments.
These strains include:
Clostridium difficile (C.diff).
Methicillin-resistant Staphylococcus aureus (MRSA).
Multidrug-resistant tuberculosis (MDR-TB).
Vancomycin-resistant Enterococcus (VRE).
These infections - which can lead to death or disability - are increasingly resistant to treatment, posing a significant global health threat. Of extra concern, is that new, more resistant strains may develop.
Use in hospitals
Hospitals are a breeding ground for infections. If you've been in hospital, you're more likely to get an infection - especially if you have a weakened immune system. This may require antibiotics, which can cause antibiotic-resistant microorganisms to thrive.
Use in agriculture
Many farmers give antibiotics to their animals to keep them healthy and help them grow faster. While some debate remains among scientists, many agree that this contributes to high rates of antibiotic resistance in farm animals.
Mohammed says: "This can lead to the spread of antibiotic-resistant bacteria to people through food, water, and the environment."
Schlechte Hygiene
Germs spread easily through person-to-person contact, interaction with animals, food consumption, close contact in healthcare settings, and poor hygiene and sanitation practices. With modern travel, an antimicrobial-resistant (AMR) threat in one location can quickly become a global issue.
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What are the implications of antibiotic resistance?
Zurück zum InhaltThe growing rate of antibiotic resistance is making infections harder to treat, prolonging illness, and requiring stronger medicines with greater side effects.
"On a larger scale, resistance complicates routine treatments and surgeries, putting strain on healthcare resources as patients need extended hospital stays," says Mohammed. "Sadly, it also leads to higher death rates, as there are fewer effective treatment options."
How are antibiotic-resistant infections treated?
Zurück zum InhaltTo treat antibiotic-resistant infections, healthcare providers may try different types of antibiotics before exploring other treatment options.
Mohammed says this can cause more side effects - or further resistance - so depending on the person, they might explore other options such as vaccines or immune-boosting treatments.
"The big challenges are that fewer effective antibiotics exist," he explains. "The bacteria are evolving faster than we can create new medicines to combat them."
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How to prevent antibiotic resistance
Zurück zum InhaltPreventing antibiotic resistance is complex, as it's influenced by a number of factors.
Mohammed says: "Public health campaigns encouraging people to use antibiotics only when necessary will help. Ensuring that your vaccinations - and those of your family members - are up to date is another important step."
He adds that reducing antibiotic use in farm animals can also help prevent resistant bacteria from reaching people.
Everyday habits can also play a crucial role in reducing the spread of antibiotic-resistant bacteria. These include practising good hand hygiene, preparing food safely, and maintaining clean environments.
Mohammed concludes: "It’s easy to think this is a government-level problem and not something people can individually help with. But that's not true. By only using antibiotics when you really need them, and finishing the full prescription, you are helping."
The Fleming Initiative
The Fleming Initiative brings together research scientists, policymakers, clinicians, behavioural experts, public, and commercial partners to provide the networks, expertise, and skills to provide equitable solutions to AMR at the global scale.
Established by Imperial College London and Imperial College Healthcare NHS Trust, the Fleming Initiative works with a wide range of commercial and philanthropic partners.
It is possible to control the spread of antibiotic resistance and keep antibiotics working, but the Fleming Initiative recognises that science must work hand-in-hand with policy and people to deliver meaningful change.
As well as developing new ways to prevent drug-resistant infections, championing new policies, and innovating on pathways of care for those infected with drug-resistant infections, the Fleming Initiative intends to change how people understand and use antibiotics. Learn more about the Fleming Initiative here and on this video.
Fleming Initiative
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20 Mar 2026 | Neueste Version
19. Nov 2024 | Ursprünglich veröffentlicht
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