Intestinal pseudo-obstruction
Zuletzt aktualisiert 12. Feb 2026
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Intestinal pseudo-obstruction is a condition characterised by impairment of the muscle contractions that move food through the digestive tract. It can occur at any time of life, and its symptoms range from mild to severe. The condition may arise from abnormalities of the gastrointestinal muscles themselves (myogenic) or from problems with the nerves that control the muscle contractions (neurogenic).
Beschreibung
Intestinal pseudo-obstruction is a condition characterised by impairment of the muscle contractions that move food through the digestive tract. It can occur at any time of life, and its symptoms range from mild to severe. The condition may arise from abnormalities of the gastrointestinal muscles themselves (myogenic) or from problems with the nerves that control the muscle contractions (neurogenic).
Intestinal pseudo-obstruction leads to a buildup of partially digested food in the intestines. This buildup can cause abdominal swelling (distention) and pain, nausea, vomiting, and constipation or diarrhea. Affected individuals experience loss of appetite and impaired ability to absorb nutrients, which may lead to malnutrition. These symptoms resemble those of an intestinal blockage (obstruction), but in intestinal pseudo-obstruction no blockage is found.
Depending on the cause of intestinal pseudo-obstruction, affected individuals can have additional signs and symptoms. Some people with intestinal pseudo-obstruction have bladder dysfunction such as an inability to pass urine. Other, additional features may include decreased muscle tone (hypotonia) or stiffness (spasticity) of the torso and limbs, weakness in the muscles that control eye movement (ophthalmoplegia), intellectual disability, seizures, unusual facial features, or recurrent infections.
When intestinal pseudo-obstruction occurs without additional features, it is called primary or idiopathic intestinal pseudo-obstruction. When the disorder occurs along with other signs and symptoms or as a complication of another health condition, it is called secondary intestinal pseudo-obstruction. The condition can occur once in a while (acute) or steadily (chronic).
Inheritance patterns
The source lists the following possible inheritance patterns: Autosomal recessive; Autosomal dominant; X-linked. More than one pattern can apply in different cases.
Related genes
Other names
Chronic idiopathic intestinal pseudo-obstruction
CIIP
CIPO
Congenital short bowel syndrome
Enteric neuropathy
Familial visceral myopathy
Familial visceral neuropathy
IPO
Paralytischer Ileus
Pseudo-obstruction of intestine
Pseudointestinal obstruction syndrome
Pseudoobstructive syndrome
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Kann ich Empagliflozin und Ballaststoffpräparate zusammen einnehmen?
Fournier’s gangrene - empagliflozin Seek immediate medical attention if you experience severe pain, tenderness, redness, or swelling in the genital or anal area, accompanied by fever or a general feeling of being unwell. Intestinal obstruction You must take fibre supplements with a large glass of water (at least 200ml). Taking them without enough.
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Reisedurchfall
Do not water down the formula, or make it up with less water than usual. Medication Loperamide is not recommended for children with diarrhoea. There are concerns that it may cause a blockage of the gut (intestinal obstruction) in Kindern with diarrhoea. Most children with traveller's diarrhoea do not need treatment with antibiotics. However, for.
Weiterführende Lektüre und Referenzen
- Intestinal pseudo-obstruction; MedlinePlus, National Library of Medicine.
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- Matera I, Rusmini M, Guo Y, Lerone M, Li J, Zhang J, Di Duca M, Nozza P, Mosconi M, Pini Prato A, Martucciello G, Barabino A, Morandi F, De Giorgio R, Stanghellini V, Ravazzolo R, Devoto M, Hakonarson H, Ceccherini I. Variants of the ACTG2 gene correlate with degree of severity and presence of megacystis in chronic intestinal pseudo-obstruction. Eur J Hum Genet. 2016 Aug;24(8):1211-5. doi: 10.1038/ejhg.2015.275. Epub 2016 Jan 27.
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12. Feb 2026 | Neueste Version
1 Dec 2017 | Ursprünglich veröffentlicht
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