SH3 and multiple ankyrin repeat domains 3
Zuletzt aktualisiert 18. Aug 2020
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Der SHANK3 gene provides instructions for making a protein that is found in many of the body's tissues but is most abundant in the brain. The SHANK3 protein plays a role in the functioning of synapses, which are the connections between nerve cells (neurons) where cell-to-cell communication occurs. Within synapses, the SHANK3 protein acts as a scaffold that supports the connections between neurons, ensuring that the signals sent by one neuron are received by another.
Normal function
Der SHANK3 gene provides instructions for making a protein that is found in many of the body's tissues but is most abundant in the brain. The SHANK3 protein plays a role in the functioning of synapses, which are the connections between nerve cells (neurons) where cell-to-cell communication occurs. Within synapses, the SHANK3 protein acts as a scaffold that supports the connections between neurons, ensuring that the signals sent by one neuron are received by another.
The SHANK3 protein is also involved in the formation and maturation of dendritic spines. Dendrites are specialized extensions from neurons that are essential for the transmission of nerve impulses. Dendritic spines are small outgrowths from dendrites that further help transmit nerve impulses and increase communication between neurons.
Conditions referring to this gene or chromosome
Other names
proline-rich synapse-associated protein 2
ProSAP2
SPANK-2
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Weiterführende Lektüre und Referenzen
- SH3 and multiple ankyrin repeat domains 3; MedlinePlus, National Library of Medicine.
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18. Aug 2020 | Neueste Version
1 Jun 2017 | Ursprünglich veröffentlicht
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