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Amlodipin-Tabletten

Istin, Norvasc

Amlodipine is taken once a day.

You can take the tablets before or after meals.

When you first start taking amlodipine you may get a headache, or feel flushed and hot. These symptoms tend to go after the first few days.

At a glance

  • Amlodipine is a medicine taken once a day for high blood pressure or to prevent angina.

  • It works by relaxing and widening blood vessels, which lowers blood pressure and reduces heart strain.

  • Common side-effects can include headache, flushing, dizziness, and swollen ankles.

  • Do not drink large quantities of grapefruit juice, as it might increase amlodipine effects.

  • If you forget a dose, take it when you remember, unless it's the next day; do not take two doses.

  • Do not stop taking amlodipine suddenly, as symptoms may return.

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About amlodipine

Art des Medikaments

Calcium-channel blocker

Verwendet für

High blood pressure; angina

Auch genannt (UK)

Istin®
Combination brands include: Exforge® (amlodipine with valsarta); Sevikar® (amlodipine with lmesartan)

Auch genannt (USA)

Norvasc®
Combination brands include: Azor® (amlodipine with olmesartan); Caduet® (amlodipine with atorvastatin); Exforge® (amlodipine with valsartan); Lotrel® (amlodipine with benazepril); Prestalia® (amlodipine with perindopril); Twynsta® (amlodipine with telmisartan)

Verfügbar als

Tablets, oral liquid medicine, capsules (USA)

Amlodipine is given to treat hoher Blutdruck (Hypertonie). It is also taken to help prevent angina chest pain. You may have been prescribed it for either of these reasons.

Amlodipine works by causing some of your blood vessels to relax and widen. This lowers your blood pressure. It also reduces the force and the rate of your heartbeat, and this helps to prevent angina chest pain. It does these things by blocking the amount of calcium that goes into the 'smooth' muscle cells in the walls of your arteries and in your heart. Calcium is needed for muscles to contract, so reducing the amount of calcium causes the muscle cells to relax.

Amlodipine is also available as a combination tablet with other medicines to reduce high blood pressure. Combination tablets help to reduce the total number of tablets you need to take each day.

Some medicines are not suitable for people with certain conditions, and sometimes a medicine may only be used if extra care is taken. For these reasons, before you start taking amlodipine it is important that your doctor knows:

  • Wenn Sie schwanger sind oder stillen.

  • Wenn Sie Probleme mit der Funktion Ihrer Leber haben.

  • Wenn Sie andere Medikamente einnehmen oder verwenden. Dazu gehören alle Medikamente, die Sie einnehmen und die ohne Rezept erhältlich sind, sowie pflanzliche und ergänzende Medikamente.

  • Wenn Sie jemals eine allergische Reaktion auf ein Medikament hatten.

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  • Before you start this treatment, read the manufacturer's printed information leaflet from inside your pack. It will give you more information about amlodipine and will provide you with a full list of the side-effects which you may experience from taking the tablets.

  • Amlodipine is taken once a day. It is usual to be prescribed the 5 mg strength tablet to take at first, although the strength of your tablets may be increased to 10 mg after a short while.

  • You can generally choose a time of day to take your tablets that you find easiest to remember, but try to take your doses at the same time of day each day. This will help you to avoid missing doses.

  • Swallow the tablet with a drink of water. You can take amlodipine before or after meals.

  • If you forget to take a dose at your usual time, take it as soon as you remember. If you do not remember until the following day, leave out the missed dose. Do not take two doses together to make up for a forgotten dose.

  • Versuchen Sie, Ihre regelmäßigen Termine mit Ihrem Arzt einzuhalten. So kann Ihr Arzt Ihren Fortschritt überprüfen.

  • Your doctor will discuss with you the possibility of unwanted side-effects. When you first start taking amlodipine you may experience headaches, feeling flushed, and some dizziness. These effects usually only last for a few days, but if they continue or become troublesome, you should let your doctor know.

  • If you drink alcohol, ask your doctor for advice. Your doctor may recommend that you do not drink alcohol while you are on this medicine, as it may increase the chance that you experience side-effects, such as feeling dizzy or light-headed.

  • Treatment with amlodipine is usually long-term unless you experience an adverse effect. Continue to take the tablets unless you are told otherwise by your doctor. If it is necessary for you to stop, your doctor may want you to reduce your dose over a few days, as suddenly stopping taking amlodipine can cause your symptoms to return.

  • If you buy any medicines, always check with a pharmacist that they are suitable to take with your other medicines. Some anti-inflammatory painkillers may reduce the effectiveness of amlodipine.

  • If you need to have an operation or any medical treatment, always tell the person carrying out the treatment which medicines you are taking. Amlodipine may interfere with the way some anaesthetics work.

  • It is not advisable for you to drink large quantities of grapefruit juice. This is because a chemical in grapefruit juice may increase the amount of amlodipine in your bloodstream and this could make side-effects more likely.

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Along with their useful effects, most medicines can cause unwanted side-effects although not everyone experiences them. The table below contains some of the most common ones associated with amlodipine. You will find a full list in the manufacturer's information leaflet supplied with your medicine. The unwanted effects often improve as your body adjusts to the new medicine, but speak with your doctor or pharmacist if any of the following continue or become troublesome.

Common

amlodipine side-effects (these affect fewer than 1 in 10 people)

Was kann ich tun, wenn ich das erlebe?

Headache, feeling flushed or hot

These may occur during the first few days but usually soon go. Speak with your doctor if they continue beyond a few days

Abdominal discomfort, feeling sick (nausea)

Stick to simple meals - avoid rich and spicy foods

Swollen ankles

Raise your legs on to a low stool when you are sitting. Speak with your doctor or a pharmacist if the swelling continues

Sich schwindelig oder müde fühlen

Wenn dies passiert, fahren Sie nicht und benutzen Sie keine Werkzeuge oder Maschinen, bis Sie sich besser fühlen

The sensation of having a 'thumping' heart (palpitations)

Wenn es problematisch ist, sprechen Sie mit Ihrem Arzt

Wenn Sie andere Symptome bemerken, die Ihrer Meinung nach auf die Tabletten zurückzuführen sein könnten, sprechen Sie mit Ihrem Arzt oder Apotheker für weitere Ratschläge.

  • Bewahren Sie alle Medikamente außerhalb der Reichweite und Sicht von Kindern auf.

  • An einem kühlen, trockenen Ort aufbewahren, fern von direkter Hitze und Licht.

Wichtige Informationen über alle Medikamente

Nehmen Sie niemals mehr als die vorgeschriebene Dosis ein. Wenn Sie vermuten, dass Sie oder jemand anderes eine Überdosis dieses Medikaments eingenommen haben könnte, gehen Sie in die Notaufnahme Ihres örtlichen Krankenhauses. Nehmen Sie den Behälter mit, auch wenn er leer ist.

Dieses Medikament ist für Sie. Geben Sie es niemals an andere Personen weiter, auch wenn deren Zustand ähnlich erscheint wie Ihrer.

Bewahren Sie keine abgelaufenen oder unerwünschten Medikamente auf. Bringen Sie sie zu Ihrer örtlichen Apotheke, die sie für Sie entsorgt.

Wenn Sie Fragen zu diesem Medikament haben, fragen Sie Ihren Apotheker.

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Häufig gestellte Fragen

How does amlodipine actually help with high blood pressure and angina?

Amlodipine works by relaxing and widening some of your blood vessels, which in turn lowers your blood pressure. For angina, it reduces the force and rate of your heartbeat. It achieves this by blocking calcium from entering 'smooth' muscle cells in your arteries and heart, as calcium is necessary for these muscles to contract.

Can I take amlodipine if I am taking other medications, including over-the-counter ones?

Yes, but it's important that your doctor knows about all other medicines you are taking, including those bought without a prescription, as well as herbal and complementary medicines. This is to ensure there are no interactions that could affect your health or the effectiveness of amlodipine. Also, be aware that some anti-inflammatory painkillers might reduce amlodipine's effectiveness.

What should I do if I forget to take a dose of amlodipine?

If you forget to take your dose at the usual time, take it as soon as you remember. However, if you don't remember until the following day, skip the missed dose and continue with your regular schedule. Do not take two doses together to make up for a forgotten dose.

Are there any specific drinks or foods I should avoid while taking amlodipine?

You should not drink large quantities of grapefruit juice while taking amlodipine. A chemical in grapefruit juice can increase the amount of amlodipine in your bloodstream, which could make side-effects more likely.

How long will I need to take amlodipine?

Treatment with amlodipine is usually long-term. You should continue taking the tablets unless your doctor tells you otherwise. If your doctor decides you need to stop, they may advise you to reduce your dose gradually over a few days, as suddenly stopping can cause your symptoms to return.

What should I do if I experience side-effects that don't go away?

When you first start amlodipine, you might experience headaches, flushing, or dizziness, which usually go away within a few days. If these, or any other side-effects, continue or become troublesome, you should let your doctor know. They can provide further advice or adjust your treatment if needed.

Weiterführende Literatur und Referenzen

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About the authorView full bio

Author image

Michael Stewart, MRPharmS

Manager für die Überprüfung von Beipackzetteln – Auftragnehmer, Apotheker

BPharm (Hons), MRPharmS

Michael ist ein Gemeindapotheker, der in den Midlands und South Yorkshire praktiziert und über mehr als 20 Jahre Erfahrung in der Beratung zu Medikamenten und medizinischen Bedingungen verfügt. Er hat einen starken Hintergrund in der Gesundheitsausbildung, da er Schulungskurse für Apothekenteams und Mitarbeiter von Pflegeeinrichtungen, einschließlich Krankenschwestern, erstellt und durchgeführt hat. Er hat auch zu Apothekenbeiräten für das Management von geringfügigen Erkrankungen in der Gemeinschaft beigetragen.

About the reviewer

Author image

Sid Dajani

Sultan Dajani qualified at the London School of Pharmacy in 1994 and became the youngest elected member of the Royal Pharmaceutical Society council since its founding in 1842.

Artikelverlauf

Die Informationen auf dieser Seite wurden von qualifizierten Klinikern verfasst und begutachtet.

  • Nächste Überprüfung fällig: 3. Juli 2026
  • 4. Juli 2023 | Neueste Version

    Zuletzt aktualisiert von

    Michael Stewart, MRPharmS

    Begutachtet von

    Sid Dajani
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