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Enzalutamid bei Prostatakrebs

Xtandi

Take four tablets together, once a day.

Swallow the tablets whole with a drink of water.

At a glance

  • Enzalutamide is an anti-androgen medicine used to treat advanced prostate cancer.

  • It works by blocking male hormones like testosterone that prostate cancer cells need to grow.

  • Take 4 tablets once daily, at the same time each day, with water.

  • You can take enzalutamide with or without food.

  • Common side-effects include feeling tired, hot flushes, and high blood pressure.

  • Tell your doctor if you have had seizures, heart problems, or kidney/liver issues before taking.

  • Enzalutamide can harm an unborn child, so use effective birth control if having sex with a woman who could become pregnant.

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About enzalutamide

Art des Medikaments

An anti-androgen medicine

Verwendet für

Advanced prostate cancer

Auch genannt

Xtandi®

Verfügbar als

Tabletten

In some men with prostate cancer, the cancer cells spread to parts of the body other than the prostate gland. When this happens, it is referred to as late, advanced or metastatic prostate cancer. Treatment options for this type of cancer typically include hormone treatment, surgery, radiotherapy and chemotherapy.

Enzalutamide is a hormone treatment - it belongs to a group of medicines known as anti-androgens. It works by blocking the action of male hormones called androgens. Testosterone is an androgen. Prostate cancer cells need the male hormone testosterone to grow and multiply well. By blocking the action of androgens such as testosterone, enzalutamide slows the growth of the cancer cells.

Some medicines are not suitable for people with certain conditions, and sometimes a medicine may only be used if extra care is taken. For these reasons, before you start taking enzalutamide it is important that your doctor knows:

  • If you have ever had a fit (seizure) or if you have been told you may be at risk of having a seizure.

  • If you have heart or blood vessel problems.

  • If you have any problems with the way your kidneys work or any problems with the way your liver works.

  • Wenn Sie andere Medikamente einnehmen oder verwenden. Dazu gehören alle Medikamente, die Sie einnehmen und die ohne Rezept erhältlich sind, sowie pflanzliche und ergänzende Medikamente.

  • Wenn Sie jemals eine allergische Reaktion auf ein Medikament hatten.

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  • Before you start the treatment, read the manufacturer's printed information leaflet from inside the pack. It will give you more information about enzalutamide and will provide you with a full list of the side-effects which you may experience from taking it.

  • Take enzalutamide exactly as your doctor tells you to. The usual dose is four 40 mg tablets taken together, once a day. Your dose will be printed on the label of the pack to remind you about what the doctor said to you.

  • Take the tablets with a drink of water. Swallow the tablets whole - do not break or chew the tablets.

  • You can take your doses either before or after food, but try to take enzalutamide at the same time of day each day. This will help you to remember to take your doses regularly.

  • If you do forget to take a dose, take it as soon as you remember. If you do not remember until the following day, skip the forgotten dose. Do not take two doses together to make up for a missed dose.

  • Versuchen Sie, Ihre regelmäßigen Termine mit Ihrem Arzt einzuhalten. So kann Ihr Arzt Ihren Fortschritt überprüfen.

  • If you buy any medicines 'over the counter', always check with a pharmacist that they are suitable for you to take with your other medicines.

  • If you are having an operation or dental treatment, tell the person carrying out the treatment that you are taking enzalutamide.

  • Enzalutamide may harm an unborn child. This means that if you are having sex with a woman who could become pregnant, you must use a condom along with another effective birth control method. If you are having sex with a woman who is already pregnant, you must use a condom to protect the unborn child.

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Along with their useful effects, most medicines can cause unwanted side-effects although not everyone experiences them. The table below contains some of the most common ones associated with enzalutamide. You will find a full list in the manufacturer's information leaflet supplied with your medicine. Speak with your doctor or pharmacist if you experience any symptoms which you think may be due to enzalutamide.

Very common enzalutamide side-effects (these affect more than 1 in 10 men)


Was kann ich tun, wenn ich das erlebe?

Sich müde oder schwach fühlen

Take a rest when needed. Do not use tools or machines while affected. Take care moving about as this medicine can put you at risk of falls.

Feeling hot and flushed

Try to keep as cool as possible by wearing light and airy clothes

Hoher Blutdruck

Your doctor will be monitoring your progress and will check for this

Common enzalutamide side-effects

(diese betreffen weniger als 1 von 10 Männern)

Was kann ich tun, wenn ich das erlebe?

Feeling anxious, memory problems, itching, dry skin, falls, breast enlargement, an urge to move your legs, an altered sense of taste

Speak with your doctor for advice

Kopfschmerzen

Trinken Sie viel Wasser und bitten Sie Ihren Apotheker, ein geeignetes Schmerzmittel zu empfehlen. Wenn die Kopfschmerzen anhalten, informieren Sie Ihren Arzt

Wenn Sie andere Symptome bemerken, die Ihrer Meinung nach auf dieses Medikament zurückzuführen sind, sprechen Sie mit Ihrem Arzt oder Apotheker für weitere Ratschläge.

  • Bewahren Sie alle Medikamente außerhalb der Reichweite und Sicht von Kindern auf.

  • An einem kühlen, trockenen Ort aufbewahren, fern von direkter Hitze und Licht.

Wichtige Informationen über alle Medikamente

Nehmen Sie niemals mehr als die vorgeschriebene Dosis ein. Wenn Sie vermuten, dass Sie oder jemand anderes eine Überdosis dieses Medikaments eingenommen haben könnte, gehen Sie in die Notaufnahme Ihres örtlichen Krankenhauses. Nehmen Sie den Behälter mit, auch wenn er leer ist.

Dieses Medikament ist für Sie. Geben Sie es niemals an andere Personen weiter, auch wenn deren Zustand ähnlich erscheint wie Ihrer.

Bewahren Sie keine abgelaufenen oder unerwünschten Medikamente auf. Bringen Sie sie zu Ihrer örtlichen Apotheke, die sie für Sie entsorgt.

Wenn Sie Fragen zu diesem Medikament haben, fragen Sie Ihren Apotheker.

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Häufig gestellte Fragen

What specifically is advanced prostate cancer and how does enzalutamide fit into its treatment?

Advanced prostate cancer means that the cancer cells have spread from the prostate gland to other parts of the body. Enzalutamide is a hormone treatment, specifically an anti-androgen, used for this type of cancer. It works by blocking male hormones like testosterone that prostate cancer cells need to grow, thereby slowing the cancer's progression.

Are there any specific medical conditions that might prevent me from taking enzalutamide?

Yes, there are some conditions your doctor needs to know about. These include if you have ever had a seizure or are at risk of one, if you have heart or blood vessel problems, or any issues with your kidneys or liver function. It's also important to tell your doctor about any allergies you have.

What should I do if I accidentally miss a dose of enzalutamide?

If you forget to take a dose, you should take it as soon as you remember. However, if you don't remember until the following day, you should skip the forgotten dose. It's important not to take two doses together to try and make up for a missed one.

What precautions should I take regarding contraception while on enzalutamide, even if my partner is pregnant?

Enzalutamide can harm an unborn child. If you are having sex with a woman who could become pregnant, you must use a condom along with another effective birth control method. If you are having sex with a woman who is already pregnant, you must still use a condom to protect the unborn child.

What are the common side effects of enzalutamide, and what should I do about them?

Very common side effects include feeling tired or weak, feeling hot and flushed, and high blood pressure. For tiredness, rest when needed and be careful moving around as it can increase the risk of falls. For hot flushes, try to stay cool by wearing light clothing. Your doctor will monitor your blood pressure. Less common side effects include anxiety, memory problems, itching, dry skin, breast enlargement, an urge to move your legs, an altered sense of taste, and headaches. For these, speak with your doctor for advice or, for headaches, drink water and ask your pharmacist about a painkiller.

How should I store enzalutamide tablets to ensure they remain effective and safe?

You should keep the tablets out of the reach and sight of children. Store them in a cool, dry place, away from direct heat and light.

What should I do if I think I've taken too much enzalutamide, or if I have old medication?

Never take more than your prescribed dose. If you suspect an overdose, you should go to the accident and emergency department of your local hospital immediately and take the medicine container with you. You should also not keep out-of-date or unwanted medicines; take them to your local pharmacy for safe disposal.

Weiterführende Literatur und Referenzen

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About the authorView full bio

Author image

Michael Stewart, MRPharmS

Manager für die Überprüfung von Beipackzetteln – Auftragnehmer, Apotheker

BPharm (Hons), MRPharmS

Michael ist ein Gemeindapotheker, der in den Midlands und South Yorkshire praktiziert und über mehr als 20 Jahre Erfahrung in der Beratung zu Medikamenten und medizinischen Bedingungen verfügt. Er hat einen starken Hintergrund in der Gesundheitsausbildung, da er Schulungskurse für Apothekenteams und Mitarbeiter von Pflegeeinrichtungen, einschließlich Krankenschwestern, erstellt und durchgeführt hat. Er hat auch zu Apothekenbeiräten für das Management von geringfügigen Erkrankungen in der Gemeinschaft beigetragen.

About the reviewer

Author image

Sid Dajani

Sultan Dajani qualified at the London School of Pharmacy in 1994 and became the youngest elected member of the Royal Pharmaceutical Society council since its founding in 1842.

Artikelverlauf

Die Informationen auf dieser Seite wurden von qualifizierten Klinikern verfasst und begutachtet.

  • Nächste Überprüfung fällig: 24. Apr. 2027
  • 18 May 2024 | Neueste Version

    Zuletzt aktualisiert von

    Michael Stewart, MRPharmS

    Begutachtet von

    Sid Dajani
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