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Nitrofurantoin for urine infections

Macrobid

Take nitrofurantoin with (or just after) a meal or a snack. This will help your body to absorb the medicine and help to prevent stomach upset.

Space out your doses evenly throughout the day, and remember to finish the course prescribed.

Nitrofurantoin can darken the colour of your urine. This is nothing to worry about.

Contact your doctor if you develop a cough with difficulty breathing and pains in your chest during treatment with nitrofurantoin.

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About nitrofurantoin

Art des Arzneimittels

An antibacterial

Verwendet für

Urinary tract infection (UTI) in adults and in children over 3 months of age

Auch genannt

Macrobid®

Verfügbar als

Tablets, capsules, prolonged-release capsules, oral liquid medicine

A urine infection is often called a urinary tract infection (or simply, UTI) by doctors. Most urine infections are caused by germs (bacteria) that come from your own bowel. They are usually easily treated with a short course of an antibacterial medicine such as nitrofurantoin. Occasionally, longer-term treatment is needed to prevent infections from coming back. Nitrofurantoin works by killing the bacteria causing the infection.

Before taking nitrofurantoin

Some medicines are not suitable for people with certain conditions, and sometimes a medicine can only be used if extra care is taken. For these reasons, before you start taking nitrofurantoin it is important that your doctor knows:

  • If you are pregnant or breastfeeding. Although nitrofurantoin can be taken during pregnancy, it is still important that you tell your doctor about being pregnant.

  • Wenn Sie Probleme mit der Funktionsweise Ihrer Leber haben oder wenn Sie Probleme mit der Funktionsweise Ihrer Nieren haben.

  • Wenn Sie Diabetes (Diabetes mellitus) haben.

  • If you have been told you have anaemia, or if you have low levels of vitamin B or folic acid.

  • Wenn Sie Atemprobleme haben.

  • If you have a problem where your nerves cause pain or numbness, called peripheral neuropathy.

  • If you have been told you have one of the following rare inherited conditions: porphyria or glucose-6-phosphate dehydrogenase (G6PD) deficiency.

  • Wenn Sie andere Arzneimittel einnehmen. Dazu gehören alle Arzneimittel, die ohne Rezept erhältlich sind, sowie pflanzliche und ergänzende Arzneimittel.

  • Wenn Sie schon einmal eine allergische Reaktion auf ein Arzneimittel hatten.

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How to take nitrofurantoin

  • Before you start the treatment, read the manufacturer's printed information leaflet from inside the pack. It will give you more information about nitrofurantoin, and will also provide you with a full list of the side-effects which you could experience from taking it.

  • Take nitrofurantoin exactly as your doctor tells you to. Your dose will depend upon whether you are being treated because you have an infection, or to prevent an infection from coming back. The directions for taking your doses will be printed on the label of the pack to remind you about what the doctor said to you.

  • Take each of your doses with a snack or after eating a meal. Space them out evenly throughout the day - this means that tablets/capsules prescribed four times a day should ideally be taken every six hours, those prescribed twice a day should be taken every 12 hours, and those prescribed once a day should be taken every 24 hours.

  • Keep taking nitrofurantoin until the course is finished. It is important you do this even if you feel well, otherwise your infection may come back. Most people taking nitrofurantoin are prescribed a short course of treatment which usually lasts between 3-7 days. If you have had several urine infections in a short period of time, your doctor will prescribe a longer course of treatment for you, often for six months.

  • If you forget to take a dose at your usual time, take it as soon as you remember. Try to take the correct number of doses each day but do not take two doses at the same time to make up for a missed dose.

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  • Most people improve within a few days of starting treatment. If your symptoms do not improve despite taking nitrofurantoin, go back to see your doctor, as you may need an alternative antibiotic. This is because some bacteria are resistant to some types of antibiotics.

  • Nitrofurantoin can turn your urine a yellow/brown colour. This is harmless.

  • If you buy any medicines, check with a pharmacist that they are suitable for you to take with nitrofurantoin. Some antacids can interfere with nitrofurantoin and stop it from working properly.

  • If you are taking the contraceptive 'pill' at the same time as this antibiotic, the effectiveness of the 'pill' can be reduced if you have a bout of sickness (vomiting) or diarrhoea which lasts for more than 24 hours. If this should happen, ask your doctor or pharmacist for advice about what additional contraceptive precautions to use over the following few days. There is no need to use additional precautions for any bouts of sickness or diarrhoea which last for less than 24 hours.

  • If you are due to have any medical or dental treatment, tell the person carrying out the treatment that you are taking nitrofurantoin. This is because it can affect the results of some diagnostic tests.

  • Nitrofurantoin can stop the oral typhoid vaccine from working. If you are due to have any vaccinations while you are taking nitrofurantoin, please make sure the person treating you knows that you are taking it.

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Can nitrofurantoin cause problems?

Along with their useful effects, most medicines can cause unwanted side-effects although not everyone experiences them. The table below contains some of the ones associated with nitrofurantoin. You will find a full list in the manufacturer's information leaflet supplied with your medicine. The unwanted effects often improve as your body adjusts to the new medicine, but speak with your doctor or pharmacist if any of the following continue or become troublesome.

Nitrofurantoin side-effects

Was kann ich tun, wenn mir das passiert?

Übelkeit (Brechreiz) oder Übelkeit (Erbrechen), Appetitlosigkeit

Stick to simple foods - avoid fatty or spicy meals. Remember to take nitrofurantoin with food

Diarrhöe

Viel Wasser trinken, um den Flüssigkeitsverlust zu ersetzen

Schwindelgefühl oder Schläfrigkeit

Fahren Sie nicht Auto und benutzen Sie keine Werkzeuge oder Maschinen, während Sie betroffen sind.

Itchy rash, allergic-type reactions, swollen salivary glands

Speak with your doctor or a pharmacist for further advice

Important: your doctor will have discussed with you the possibility of a less common side-effect that may affect your lungs. You should let your doctor know straightaway if you experience any of the following:

  • Any difficulty breathing, pains in your chest, coughing, chills, or a high temperature (fever).

Wenn Sie andere Symptome haben, von denen Sie glauben, dass sie auf das Arzneimittel zurückzuführen sind, sprechen Sie mit Ihrem Arzt oder Apotheker, um weiteren Rat zu erhalten.

How to store nitrofurantoin

  • Bewahren Sie alle Arzneimittel außerhalb der Reichweite und Sichtweite von Kindern auf.

  • An einem kühlen, trockenen Ort aufbewahren, vor direkter Hitze und Licht schützen.

  • The liquid medicine lasts for 30 days after first opening.

Wichtige Informationen über alle Arzneimittel

Wichtige Informationen über alle Arzneimittel

Nehmen Sie niemals mehr als die verordnete Dosis ein. Wenn Sie den Verdacht haben, dass Sie oder jemand anderes eine Überdosis dieses Arzneimittels eingenommen haben könnte, suchen Sie sofort die Notaufnahme Ihres örtlichen Krankenhauses auf. Nehmen Sie den Behälter mit, auch wenn er leer ist.

Dieses Arzneimittel ist für Sie bestimmt. Geben Sie es niemals anderen Menschen, auch wenn deren Zustand derselbe zu sein scheint wie Ihrer.

Bewahren Sie abgelaufene oder nicht mehr benötigte Arzneimittel nicht auf. Bringen Sie sie zu Ihrer örtlichen Apotheke, die sie für Sie entsorgt.

Wenn Sie Fragen zu diesem Arzneimittel haben, wenden Sie sich an Ihren Arzt oder Apotheker.

Nebenwirkungen eines Medikaments oder Impfstoffs melden

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Weiterführende Literatur und Referenzen

Artikel Geschichte

Die Informationen auf dieser Seite wurden von qualifizierten Klinikern verfasst und von Fachleuten geprüft.

  • Next review due: 5 Apr 2028
  • 5 Apr 2025 | Latest version

    Zuletzt aktualisiert von

    Michael Stewart, MRPharmS

    Peer-Review durch

    Sid Dajani
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