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Pilocarpin-Tabletten

Salagen

Take pilocarpine during a meal. Swallow the tablet with a large glass of water.

The tablets may reduce your ability to see clearly in poor lighting. Do not drive at night if you are affected.

The most common side-effects include headache, sweating, flu-like symptoms and passing urine more frequently.


At a glance

  • Pilocarpine is a medicine that helps stimulate glands to produce more saliva and tears.

  • It is used to relieve dry mouth after radiotherapy or with Sjögren's syndrome.

  • It can also relieve dry eyes in people with Sjögren's syndrome.

  • Take tablets exactly as directed by your doctor, with a large glass of water.

  • Common side-effects include headache, increased sweating, and blurred vision.

  • Speak to your doctor if side-effects continue or become troublesome.

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About pilocarpine

Art des Medikaments

A cholinergic medicine

Verwendet für

Dry mouth after radiotherapy; dry mouth and dry eyes in Sjögren's syndrome

Auch genannt

Salagen®

Verfügbar als

Tabletten

Pilocarpine is prescribed to relieve trockener Mund (sometimes called xerostomia) brought on by radiotherapy to the head or neck.

Pilocarpine can also be used to relieve some of the symptoms of Sjögren-Syndrom. Sjögren's syndrome can cause various symptoms, the most common being dry eyes and dry mouth. These symptoms are due to lack of secretions from glands in your body.

Pilocarpine tablets stimulate your glands to produce more saliva and tears.

Some medicines are not suitable for people with certain conditions, and sometimes a medicine can only be used if extra care is taken. For these reasons, before you start taking pilocarpine it is important that your doctor knows:

  • Wenn Sie schwanger sind oder stillen.

  • Wenn Sie eine Herzkrankheit oder Gefäßerkrankung haben.

  • If you have a problem with the way your kidneys work, or a problem with the way your liver works.

  • If you have asthma, COPD, or any other breathing problem.

  • If you have a stomach ulcer, gallstones, or a problem with your bile duct.

  • If you have an eye condition such as increased pressure in your eye (glaucoma), or inflammation of the iris of your eye (iritis).

  • If you get confused easily.

  • Wenn Sie andere Medikamente einnehmen oder verwenden. Dazu gehören alle Medikamente, die Sie einnehmen und die ohne Rezept erhältlich sind, sowie pflanzliche und ergänzende Medikamente.

  • Wenn Sie jemals eine allergische Reaktion auf ein Medikament hatten.

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  • Before you start the treatment, read the manufacturer's printed information leaflet from inside the pack. It will give you more information about pilocarpine, and will also provide you with a full list of side-effects which you could experience from taking it.

  • Your doctor will tell you how often to take the tablets - take them exactly as your doctor directs. As a guide:

    • If you are taking pilocarpine following radiotherapy, it is likely you will be prescribed one tablet three times daily to begin with. Take your doses during (or straight after) a meal, and make sure you take your last dose of the day with your evening meal.

    • If you are taking pilocarpine because you have Sjögren's syndrome, the usual dose is one tablet four times daily. Take a tablet with each of your three main meals, and also one at bedtime. Although these are the usual starting doses for people taking pilocarpine, your doctor may increase your dose if it is appropriate for you.

  • Every time you take a tablet, drink a large glass of water with it. This is to prevent you from becoming dehydrated, as pilocarpine can make you sweat more than usual.

  • If you forget to take a dose, take it as soon as you remember unless your next dose is due. If it is nearly time for your next dose, don't take the forgotten dose but instead wait and take the next dose as normal. Do not take two doses together to make up for the missed dose.

  • Versuchen Sie, Ihre regelmäßigen Termine mit Ihrem Arzt einzuhalten. So kann Ihr Arzt Ihren Fortschritt überprüfen.

  • If after taking pilocarpine for a couple of months you feel that your condition has not greatly improved, you should let your doctor know about this. Pilocarpine will not be effective if the glands in your mouth or eyes cannot be sufficiently stimulated to produce more saliva or tears.

  • If you are due to have an operation or any dental treatment, please tell the person carrying out the treatment that you are taking pilocarpine.

  • If you buy any medicines 'over the counter', check with a pharmacist that they are suitable for you to take alongside pilocarpine.

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Along with their useful effects, most medicines can cause unwanted side-effects although not everyone experiences them. The table below contains the most common ones associated with pilocarpine. You will find a full list in the manufacturer's information leaflet supplied with your medicine. The unwanted effects often improve as your body adjusts to the new medicine, but speak with your doctor or pharmacist if any continue or become troublesome.

Common and very common pilocarpine side-effects (some can affect more than 1 in 10 people)

Was kann ich tun, wenn ich das erlebe?

Kopfschmerzen

Trinken Sie viel Wasser und bitten Sie Ihren Apotheker, ein geeignetes Schmerzmittel zu empfehlen. Wenn die Kopfschmerzen anhalten, informieren Sie Ihren Arzt

Increased sweating and flushing

Take care not to become overheated during exercise or hot weather. Drink several large glasses of water every day

Blurred vision, eye irritation or pain, watery eyes

Do not drive and do not use tools or machines if you cannot see clearly (particularly at night or if you have difficulty seeing in poor lighting)

Diarrhoea, constipation, tummy ache (abdominal pain)

Try to eat a well-balanced diet. Drink plenty of water

Indigestion, feeling sick (nausea) or being sick (vomiting)

Iss einfache Speisen - vermeide reichhaltige oder scharfe Mahlzeiten

Schwindelig oder schwach fühlen

Sit down for a few minutes until you feel better. Do not drive and do not use tools or machines while affected

Increased frequency of passing urine,

high blood pressure, the sensation of having a 'thumping' heart (palpitations), flu-like symptoms, runny nose, allergic

reactions such as skin rash and itchiness

Wenn eines dieser Probleme auftritt, sprechen Sie mit Ihrem Arzt

Wenn Sie andere Symptome bemerken, die Ihrer Meinung nach auf die Tabletten zurückzuführen sein könnten, sprechen Sie mit Ihrem Arzt oder Apotheker für weitere Ratschläge.

  • Bewahren Sie alle Medikamente außerhalb der Reichweite und Sicht von Kindern auf.

  • An einem kühlen, trockenen Ort aufbewahren, fern von direkter Hitze und Licht.

Wichtige Informationen über alle Medikamente

Nehmen Sie niemals mehr als die vorgeschriebene Dosis ein. Wenn Sie vermuten, dass Sie oder jemand anderes eine Überdosis dieses Medikaments eingenommen haben könnte, gehen Sie in die Notaufnahme Ihres örtlichen Krankenhauses. Nehmen Sie den Behälter mit, auch wenn er leer ist.

Dieses Medikament ist für Sie. Geben Sie es niemals an andere Personen weiter, auch wenn deren Zustand ähnlich erscheint wie Ihrer.

Bewahren Sie keine abgelaufenen oder unerwünschten Medikamente auf. Bringen Sie sie zu Ihrer örtlichen Apotheke, die sie für Sie entsorgt.


Wenn Sie Fragen zu diesem Medikament haben, fragen Sie Ihren Apotheker.

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Häufig gestellte Fragen

What is pilocarpine and what does it do?

Pilocarpine is a type of medicine known as a cholinergic medicine. It helps to stimulate glands in your body to produce more saliva and tears, which can relieve dry mouth and dry eyes. It is prescribed for dry mouth after radiotherapy and for dry mouth and dry eyes caused by Sjögren's syndrome.

How should I take pilocarpine with food?

If you are taking pilocarpine after radiotherapy, you should take your doses during or straight after a meal, with your last daily dose taken with your evening meal. If you have Sjögren's syndrome, take a tablet with each of your three main meals and another at bedtime. Always drink a large glass of water with each tablet to prevent dehydration, as the medicine can increase sweating.

What should I do if I miss a dose of pilocarpine?

If you forget to take a dose, take it as soon as you remember, unless it's nearly time for your next scheduled dose. In that case, skip the missed dose and continue with your regular dosing schedule. Do not take two doses together to compensate for a missed dose.

How long does it take for pilocarpine to start working?

The article suggests that if, after taking pilocarpine for a couple of months, you feel your condition hasn't greatly improved, you should inform your doctor. This implies it may take some time to assess effectiveness.

Are there any specific activities I should avoid while taking pilocarpine?

If you experience blurred vision, eye irritation, or pain, you should not drive or use tools or machines, particularly at night or in poor lighting. If you feel dizzy or weak, sit down until you feel better before driving or operating machinery. Also, be careful not to overheat during exercise or hot weather because pilocarpine can increase sweating.

Can I take other medicines, including over-the-counter ones, with pilocarpine?

It is important to tell your doctor about all medicines you are currently taking, including those bought without a prescription, as well as herbal and complementary medicines. If you buy any over-the-counter medicines, check with a pharmacist to make sure they are safe to take alongside pilocarpine.

When should I tell a healthcare professional that I am taking pilocarpine?

You should inform the person carrying out the treatment that you are taking pilocarpine if you are due to have an operation or any dental treatment.

Weiterführende Literatur und Referenzen

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About the authorView full bio

Author image

Michael Stewart, MRPharmS

Manager für die Überprüfung von Beipackzetteln – Auftragnehmer, Apotheker

BPharm (Hons), MRPharmS

Michael ist ein Gemeindapotheker, der in den Midlands und South Yorkshire praktiziert und über mehr als 20 Jahre Erfahrung in der Beratung zu Medikamenten und medizinischen Bedingungen verfügt. Er hat einen starken Hintergrund in der Gesundheitsausbildung, da er Schulungskurse für Apothekenteams und Mitarbeiter von Pflegeeinrichtungen, einschließlich Krankenschwestern, erstellt und durchgeführt hat. Er hat auch zu Apothekenbeiräten für das Management von geringfügigen Erkrankungen in der Gemeinschaft beigetragen.

About the reviewer

Author image

Sid Dajani

Sultan Dajani qualified at the London School of Pharmacy in 1994 and became the youngest elected member of the Royal Pharmaceutical Society council since its founding in 1842.

Artikelverlauf

Die Informationen auf dieser Seite wurden von qualifizierten Klinikern verfasst und begutachtet.

  • Nächste Überprüfung fällig: 5. Feb 2028
  • 5. Feb. 2025 | Neueste Version

    Zuletzt aktualisiert von

    Michael Stewart, MRPharmS

    Begutachtet von

    Sid Dajani
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