Progesteron
Cyclogest, Utrogestan
Begutachtet von Sid DajaniZuletzt aktualisiert von Michael Stewart, MRPharmSLast updated 9. Jan. 2023
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Progesterone is a natural female sex hormone.
Follow carefully the directions your doctor gives to you about taking progesterone. It is prescribed for a selected number of days each month.
Any side-effects are usually mild, but may include feeling sick (nausea), weight gain, and headache.
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About progesterone
Art des Medikaments | A progestogen |
Verwendet für | A variety of gynaecological problems, including infertility, in early pregnancy, and as part of hormone replacement therapy (HRT) |
Auch genannt | Crinone® vaginal gel; Cyclogest® pessaries; Lubion® injection; Lutigest® vaginal tablets; Utrogestan® capsules and vaginal capsules |
Verfügbar als | Capsules, vaginal gel, vaginal capsules, pessaries and injection |
Progesterone is a naturally occurring female sex hormone which is essential for the function of the female reproductive system. It is produced in the ovaries during the second half of the menstrual cycle, and also by the placenta during pregnancy. The amount of progesterone a woman produces declines during the menopause.
You will have been prescribed progesterone to supplement your naturally produced progesterone for a reason which your doctor will have explained to you. It works by adjusting the balance of your body's own hormones.
Progesterone is available in a number of formulations that are the subject of this leaflet (gel, injection, capsules, and pessaries). Each formulation is prescribed for a different gynaecological reason.
Progesterone may also be included as an ingredient in a number of combination products used for a variety of medical reasons. These products are not covered by this leaflet and you should read the printed information provided by your doctor and the manufacturer.
Before taking progesterone
Zurück zum InhaltSome medicines are not suitable for people with certain conditions, and sometimes a medicine may only be used if extra care is taken. For these reasons, before you start taking progesterone, it is important that your doctor knows:
Wenn Sie schwanger sind oder stillen.
If you have migraines, asthma, epilepsy or high blood pressure.
If you are having any vaginal bleeding other than your normal monthly period.
If you have ever had a blood clot in your legs or lungs.
Wenn Sie eine Herzkrankheit haben.
If you have had any problems with the way your liver or kidneys work.
Wenn Sie jemals an Depressionen gelitten haben.
If you have too much sugar in your blood (diabetes mellitus).
Wenn Sie Krebs haben.
If during a pregnancy you had problems such as severe itching, yellowing of your skin or of the whites of your eyes (jaundice), or a skin condition called pemphigoid gestationis.
Wenn Sie eine seltene erbliche Bluterkrankung namens Porphyrie haben.
Wenn Sie jemals eine allergische Reaktion auf ein Medikament hatten.
Wenn Sie andere Medikamente einnehmen oder verwenden. Dazu gehören alle Medikamente, die Sie einnehmen und die ohne Rezept erhältlich sind, sowie pflanzliche und ergänzende Medikamente.
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How to take progesterone
Zurück zum InhaltBefore you start this treatment, read the manufacturer's printed information leaflet from inside your pack. The leaflet will give you more information about the brand of progesterone you have been given. It will also provide a full list of side-effects which you may experience.
Follow carefully the instructions your doctor has given you. Progesterone is usually only used on a number of specified days during a monthly cycle. This may range from 4 to 25 days of a month depending on the reason it has been prescribed for you. If you are unsure about what to do, check again with your doctor.
If you have been prescribed:
Utrogestan® capsules as HRT: these should be taken at bedtime, on an empty stomach. This means that you should not take them with or soon after eating food. Just take them on the days of the month your doctor has told you to. You will also be prescribed an oestrogen-containing HRT medicine to take throughout the month.
Utrogestan vaginal® capsules for fertility treatment: use the applicator and follow the manufacturer's instructions for inserting the capsule high into the vagina. Do not take the capsule by mouth, although if you do swallow it accidentally, it will not harm you. The capsules are usually prescribed during the first three months of pregnancy only.
Lutigest® vaginal tablets for fertility treatment: put one tablet into the end of the applicator and use it to insert the tablet into the vagina following the manufacturer's instructions. Push the plunger to release the tablet. The usual dose is one tablet inserted three times daily starting on the day of egg retrieval. You will need to continue using Lutigest® for 30 days if pregnancy is confirmed. Follow the instructions of your doctor.
Crinone® vaginal gel for fertility treatment: use one 'applicatorful' daily into the vagina. Just use it on the days of the month your doctor has told you to.
Cyclogest® pessaries for menstrual problems: use twice daily on the days of the month your doctor has told you to. Pessaries are generally designed to be inserted into the vagina, but Cyclogest® pessaries are also suitable to be inserted into the back passage, as a suppository. If you are unsure which is the correct way for you to use them, check again with your doctor.
Lubion® injection for fertility treatment: make sure you know how to use this injection. If you are unsure which days to use it, or how much to use, check again with your doctor or clinic.
Das Beste aus Ihrer Behandlung herausholen
Zurück zum InhaltTry to keep your regular appointments with your doctor. This is so your doctor can check on your progress. Also, remember to keep any routine appointments for breast screening and cervical smear tests.
If you are having an operation or dental treatment, tell the person carrying out the treatment that you are on progesterone.
If you have diabetes you may need to check your blood glucose more frequently, as progesterone can affect the levels of sugar in your blood. Your doctor will advise you about this.
It is best to avoid smoking and drinking too much alcohol while on progesterone. If you are a smoker and you would like advice on how to quit, speak with your doctor or pharmacist.
If you buy any medicines, check with a pharmacist that they are suitable to take with progesterone. This is because some herbal preparations (such as St John's wort) can interfere with the way it works.
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Can progesterone cause problems?
Zurück zum InhaltAlong with their useful effects, all medicines can cause unwanted side-effects although not everyone experiences them. The table below lists some of the most common ones associated with progesterone. You will find a full list in the manufacturer's information leaflet supplied with your medicine. The unwanted effects often improve over the first few days of taking or using a new medicine, but speak with your doctor or pharmacist if any of the following side-effects continue or become troublesome.
Common progesterone side-effects | Was kann ich tun, wenn ich das erlebe? |
Übelkeit (Nausea) | Iss einfache Mahlzeiten (vermeide reichhaltige oder scharfe Speisen) |
Kopfschmerzen | Ask your pharmacist to recommend a suitable painkiller. If the headaches continue or are unusually severe, speak with your doctor as soon as possible |
Irregular periods, breast tenderness, weight changes, feeling dizzy or sleepy, difficulty sleeping, changes in sexual desire, mood changes, skin rash, acne-like spots, changes in hair growth, swollen feet and ankles (due to fluid retention) | Sprechen Sie mit Ihrem Arzt, wenn eines dieser Probleme auftritt |
Wenn Sie andere Symptome bemerken, die Ihrer Meinung nach auf dieses Medikament zurückzuführen sind, sprechen Sie mit Ihrem Arzt oder Apotheker.
How to store progesterone
Zurück zum InhaltBewahren Sie alle Medikamente außerhalb der Reichweite und Sicht von Kindern auf.
An einem kühlen, trockenen Ort aufbewahren, fern von direkter Hitze und Licht.
Wichtige Informationen über alle Medikamente
Zurück zum InhaltWichtige Informationen über alle Medikamente
Nehmen Sie niemals mehr als die vorgeschriebene Dosis ein. Wenn Sie vermuten, dass Sie oder jemand anderes eine Überdosis dieses Medikaments eingenommen haben könnte, gehen Sie in die Notaufnahme Ihres örtlichen Krankenhauses. Nehmen Sie den Behälter mit, auch wenn er leer ist.
Dieses Medikament ist für Sie. Geben Sie es niemals an andere Personen weiter, auch wenn deren Zustand ähnlich erscheint wie Ihrer.
Bewahren Sie keine abgelaufenen oder unerwünschten Medikamente auf. Bringen Sie sie zu Ihrer örtlichen Apotheke, die sie für Sie entsorgt.
Wenn Sie Fragen zu diesem Medikament haben, fragen Sie Ihren Apotheker.
Berichten Sie Nebenwirkungen eines Medikaments oder Impfstoffs
Wenn Sie Nebenwirkungen bemerken, können Sie diese online über die Yellow Card website.

Unsicher beim Mischen von Medikamenten?
Überprüfen Sie mögliche Wechselwirkungen zwischen Medikamenten, Nahrungsergänzungsmitteln und Lebensmitteln, bevor Sie sie zusammen einnehmen.
Weiterführende Literatur und Referenzen
- Manufacturer's PIL, Cyclogest® 200 mg Pessaries; L.D. Collins & Co. Ltd, The electronic Medicines Compendium. Dated March 2022.
- Manufacturer's PIL, Utrogestan® 100 mg Capsules; Besins Healthcare (UK) Ltd, The electronic Medicines Compendium. Dated February 2022.
- Manufacturer's PIL, Utrogestan Vaginal® 200 mg Capsules; Besins Healthcare (UK) Ltd, The electronic Medicines Compendium. Dated July 2022.
- Manufacturer's PIL, Crinone® 8% Progesterone Vaginal Gel; Merck Serono Ltd, The electronic Medicines Compendium. Dated December 2020.
- Manufacturer's PIL, Lutigest® vaginal tablets; Ferring Pharmaceuticals Ltd, The electronic Medicines Compendium. Dated October 2014.
- Medikamente Komplett BNF 89. Ausgabe; Britische Ärztevereinigung und Königliche Pharmazeutische Gesellschaft von Großbritannien, London.
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Artikelverlauf
Die Informationen auf dieser Seite wurden von qualifizierten Klinikern verfasst und begutachtet.
Nächste Überprüfung fällig: 8. Juli 2027
9. Jan. 2023 | Neueste Version

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