Can I take Venlafaxine and Sildenafil together?

Warum das passiert

Sildenafil works by widening blood vessels to increase blood flow, which can lower blood pressure. Venlafaxine can also cause changes in blood pressure (usually an increase, but sometimes a drop when standing up). When used together, these effects can lead to an unpredictable drop in blood pressure. Furthermore, venlafaxine is an antidepressant that can cause sexual dysfunction, potentially counteracting the desired effects of sildenafil.

You should use this combination with caution. When starting sildenafil or increasing your dose, be mindful of how you feel when standing up from a sitting or lying position. If you feel dizzy or faint, sit or lie down immediately. It is best to avoid or strictly limit alcohol, as it can worsen these side effects. If you find that sildenafil is not working well for you, or if you experience severe dizziness, speak to your doctor.

Depressionen und Angststörungen

Venlafaxine can cause an increase in suicidal thoughts or self-harm, particularly when first starting treatment or changing doses. Monitor your mood closely and seek urgent medical help if you notice any distressing changes.

Verwendung von Nitratmedikamenten

NEVER take sildenafil if you use nitrate medicines for chest pain (e.g. glyceryl trinitrate, isosorbide mononitrate) or 'poppers'. Combining them causes a dangerous, potentially fatal drop in blood pressure.

Blutungsstörungen

Venlafaxine can increase your risk of bleeding, especially if you are also taking aspirin, NSAIDs (like ibuprofen), or blood-thinning medicines like warfarin. Seek medical advice if you notice unusual bruising or bleeding.

Plötzlicher Sehverlust oder Priapismus

Suchen Sie sofort medizinische Hilfe auf, wenn Sie einen plötzlichen Sehverlust oder eine plötzliche Verschlechterung der Sicht bemerken oder wenn Sie eine Erektion haben, die länger als 4 Stunden anhält.

Serotonin-Syndrom

Combining venlafaxine with other medicines that affect serotonin (such as St John's Wort or certain painkillers) can cause a life-threatening condition called serotonin syndrome. Symptoms include agitation, hallucinations, fast heartbeat, and muscle stiffness.

Alkohol

It is best to avoid or strictly limit alcohol while taking venlafaxine. Combining alcohol with this medicine can increase drowsiness, dizziness, and the risk of coordination problems. It may also worsen the symptoms of your underlying condition.

It is best to avoid or strictly limit alcohol when taking sildenafil. Alcohol can make it more difficult to get an erection and can also increase the risk of side effects such as dizziness and low blood pressure.

Grapefruitsaft

Grapefruit juice can increase the amount of sildenafil in your bloodstream. This makes side effects like headaches, flushing, or low blood pressure more likely. It is best to avoid drinking large amounts of grapefruit juice while using this medicine.

Fettreiche Mahlzeiten

If you take sildenafil with a heavy or high-fat meal (such as a burger or chips), the medicine may take longer to start working.

Koffein

Venlafaxine can sometimes increase your blood pressure or heart rate. Consuming high amounts of caffeine (found in coffee, tea, and energy drinks) may worsen these effects or increase feelings of anxiety and restlessness.

Taking multiple medicines? Our Wechselwirkungs-Checker für Medikamente helps you check whether your prescriptions, over-the-counter medicines, and supplements are safe to take together. Simply search for your medicines to see potential interactions and what to do about them.

Haftungsausschluss

Diese Informationen dienen nur allgemeinen Bildungszwecken und sollten nicht als Ersatz für professionelle medizinische Beratung herangezogen werden. Konsultieren Sie immer Ihren Hausarzt, Apotheker oder einen anderen qualifizierten Gesundheitsfachmann, bevor Sie Entscheidungen über Ihre Medikamente treffen. Individuelle Umstände können variieren, und nur ein Gesundheitsfachmann, der Ihre Krankengeschichte kennt, kann personalisierte Beratung bieten.