Can I take Vitamin B2 and Vitamin C together?
Drug interaction guide
Originally published 25 Jan 2026
Meets Patient’s editorial guidelines
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There is no evidence of a harmful interaction between Vitamin B2 (riboflavin) and Vitamin C (ascorbic acid). In fact, these two vitamins are often found together in multivitamin supplements and naturally in many fruits and vegetables.
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Why this happens
Vitamin B2 and Vitamin C are both water-soluble vitamins that are processed by the body in different ways. They do not compete for absorption in the gut, nor do they interfere with how each other is broken down or removed from the body. They have complementary roles in supporting the immune system and energy production.
What you should do
Back to contentsIt is safe to take Vitamin B2 and Vitamin C together. You do not need to space them apart. As with all supplements, ensure you do not exceed the recommended daily allowance unless advised by a healthcare professional.
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Important precautions
Back to contentsKidney stones (oxalate)
High doses of vitamin C can increase the amount of oxalate in your urine, which significantly raises the risk of developing kidney stones, especially if you have had them before.
G6PD deficiency
If you have a G6PD deficiency (a genetic enzyme condition), high doses of vitamin C can cause your red blood cells to break down (haemolysis).
Food and drink warnings
Back to contentsAlcohol
It is best to avoid or strictly limit alcohol when taking these vitamins. Alcohol can interfere with the absorption of Vitamin B2 and Vitamin C in the gut and increases the rate at which your body flushes them out, making the supplements less effective. Combining alcohol with any medicine also increases the risk of liver strain.
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Using other medicines
Back to contentsTaking multiple medicines? Our Medicines Interaction Checker helps you check whether your prescriptions, over-the-counter medicines, and supplements are safe to take together. Simply search for your medicines to see potential interactions and what to do about them.
Disclaimer
This information is for general educational purposes only and should not be relied upon as a substitute for professional medical advice. Always consult your GP, pharmacist, or another qualified healthcare professional before making decisions about your medications. Individual circumstances may vary, and only a healthcare professional who knows your medical history can provide personalised guidance.
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Treatment and medication
Can I take Atorvastatin and Turkey tail together?
There is no evidence of a direct harmful interaction between atorvastatin and turkey tail mushroom (Trametes versicolor). However, turkey tail may have a mild effect on how the liver processes certain medications, and it may also have its own subtle cholesterol-lowering properties.
Treatment and medication
Can I take Colecalciferol and Ezetimibe together?
There is no known significant interaction between colecalciferol (Vitamin D3) and ezetimibe. Taking these two medications together is generally considered safe.
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Article history
The information on this page is written and peer reviewed by qualified clinicians.
25 Jan 2026 | Originally published
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