Agomelatin-Tabletten

About agomelatine

Depression is common. Symptoms can affect day-to-day life and can become very distressing. Treatments include talking (psychological) treatments and antidepressant medicines.

Our bodies have a number of important physical and behavioural processes which are controlled by the cycling of day and night. These are called circadian rhythms and, if disrupted, can result in depression. Agomelatine relieves depression by helping to restore the balance of these biological rhythms.

Before taking agomelatine

Some medicines are not suitable for people with certain conditions, and sometimes a medicine can only be used if extra care is taken. For these reasons, before you start taking agomelatine it is important that your doctor knows:

• Wenn Sie unter 18 oder über 75 Jahre alt sind.

• Wenn Sie schwanger sind oder stillen.

• Wenn Sie Probleme mit der Funktionsweise Ihrer Leber haben oder wenn Sie Probleme mit der Funktionsweise Ihrer Nieren haben.

• If you have ever had abnormally 'high' moods or dementia.

• If you regularly drink large amounts of alcohol.

• Wenn Sie andere Arzneimittel einnehmen. Dazu gehören alle Arzneimittel, die ohne Rezept erhältlich sind, sowie pflanzliche und ergänzende Arzneimittel.

• Wenn Sie schon einmal eine allergische Reaktion auf ein Arzneimittel hatten.

How to take agomelatine

• Before you start the treatment, read the manufacturer's printed information leaflet from inside the pack. It will give you more information about agomelatine, and will also provide you with a full list of the side-effects which you could experience from taking it.

• Take agomelatine exactly as your doctor tells you to. The usual dose is one tablet daily. This may be increased in some people to two tablets daily (taken together) after a couple of weeks. You should take the tablets at bedtime. The tablets can be taken either with or without food.

• If you forget to take a dose, do not worry, just take the next dose when it is due.
  

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• It can take a week or two after starting the tablets before the effect begins to build up, and maybe a few weeks longer before you feel the full benefit from the treatment. Do not stop taking agomelatine after a few days, thinking it is not helping.

• Try to keep your regular appointments with your doctor. This is because your doctor will want you to have a blood test every few weeks to check that your liver is staying healthy. Your doctor will also give you a booklet to read which explains about what symptoms to look out for as signs that the medicine could be harming your liver. There is a list of these symptoms in the section below on the problems which can be caused by agomelatine.

• While you feel depressed or are taking agomelatine, you may have thoughts about harming yourself or ending your life. It is very important that you tell your doctor about this straightaway if it happens to you.

• Taking agomelatine and alcohol is not recommended, so do not drink alcohol during your treatment with this medicine.

• Smoking can affect the amount of agomelatine in your body. Let your doctor know if you either start or stop smoking while you are taking agomelatine.

• Your doctor will ask you to carry on taking agomelatine for a while after you feel better. This is to stop your symptoms from returning.

• There are several types of antidepressants and they differ in their possible side-effects. If you find that agomelatine does not suit you then let your doctor know, as another could be found that will suit you.

Can agomelatine cause problems?

Along with their useful effects, most medicines can cause unwanted side-effects although not everyone experiences them. The table below contains some of the most common ones associated with agomelatine. You will find a full list in the manufacturer's information leaflet supplied with your medicine. The unwanted effects often improve as your body adjusts to the new medicine, but speak with your doctor or pharmacist if any of the following continue or become troublesome.

Wenn Sie andere Symptome haben, von denen Sie glauben, dass sie auf die Tabletten zurückzuführen sind, sprechen Sie mit Ihrem Arzt oder Apotheker, um weiteren Rat zu erhalten.

How to store agomelatine

• Bewahren Sie alle Arzneimittel außerhalb der Reichweite und Sichtweite von Kindern auf.

• An einem kühlen, trockenen Ort aufbewahren, vor direkter Hitze und Licht schützen.
  

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