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Gemfibrozil bei Hyperlipidämie

Lopid

Gemfibrozil reduces fat (lipid) levels. Take your doses about half an hour before a meal.

Some lifestyle changes will also help to reduce your lipid level - eat healthy food, stop smoking, increase the exercise you take, and reduce the amount of salt in your diet.

The most common side-effect is indigestion. If you develop any unusual aches and pains in your muscles, contact your doctor for advice.

At a glance

  • Gemfibrozil is a medicine that helps lower high levels of fats in your blood.

  • It is often prescribed for high triglyceride levels or if statins are not suitable.

  • Take gemfibrozil exactly as prescribed, usually before breakfast and your evening meal.

  • Tell your doctor if you develop any muscle aches or pains, especially in your legs.

  • Regular blood tests will be needed to check your progress.

  • Taking gemfibrozil works best alongside a healthy lifestyle.

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About gemfibrozil

Art des Medikaments

A lipid-regulating medicine commonly known as a fibrate

Verwendet für

Hyperlipidaemia (adults)

Auch genannt

Lopid®

Verfügbar als

Tablets (600 mg) and capsules (300 mg)

Lipid is another word for fat. Cholesterol and triglycerides are types of lipid. When the concentration of lipids in your blood is too high, it is called Hyperlipidämie. Lipids are made naturally in our bodies and are also absorbed from the food we eat. If the levels of lipids are too high, the excess fat is deposited on to the walls of our blood vessels. This can lead to patches like small fatty lumps developing within the lining of some blood vessels. These patches can reduce the flow of blood, and lead to heart disease, stroke, and blood circulation problems.

High levels of lipids do not make people feel ill, but they can cause the problems mentioned above if left untreated. By lowering the levels of fats, gemfibrozil helps to prevent these long-term heart and circulation problems. Your treatment will be more successful if you also follow the healthy lifestyle advice given by your doctor.

It is likely that you will be prescribed gemfibrozil if you have a high level of a lipid called triglyceride. It may also be given for other types of hyperlipidaemia, especially if other medicines (called statins) are not suitable for you.

Some medicines are not suitable for people with certain conditions, and sometimes a medicine can only be used if extra care is taken. For these reasons, before you start taking gemfibrozil it is important that your doctor knows:

  • Wenn Sie schwanger sind, versuchen, schwanger zu werden oder stillen.

  • If you have problems with the way your kidneys work, or problems with the way your liver works.

  • If you have bile and gallbladder problems, or gallstones.

  • Wenn Sie eine unteraktive Schilddrüse haben.

  • Wenn Sie Diabetes haben.

  • Wenn Sie andere Medikamente einnehmen. Dazu gehören alle Medikamente, die Sie einnehmen und die ohne Rezept erhältlich sind, sowie pflanzliche und ergänzende Medikamente.

  • If you have ever had an allergic or bad reaction to a medicine.

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  • Before you start the treatment, read the manufacturer's printed information leaflet from inside the pack. It will give you more information about gemfibrozil, and it will also provide you with a full list of the side-effects which you could experience from taking it.

  • Take gemfibrozil exactly as your doctor tells you to. There are two strengths of gemfibrozil available - a 300 mg capsule and a 600 mg tablet. It is usual to be prescribed 600 mg twice daily (as tablets). Take your doses ½-1 hour before a meal. This is because gemfibrozil is absorbed better when your stomach is empty. It is best to take gemfibrozil with the same meals each day, as this helps remind you to take your doses regularly. The ideal times to take your doses are before your breakfast and evening meal. If your doctor feels that a lower dose would be more suitable for you, your dose will be 900 mg (as one tablet and one capsule) taken once daily, ½-1 hour before your evening meal.

  • Swallow the tablets/capsules whole with a drink of water. Do not break the tablets or open the capsules, as they have an unpleasant taste.

  • If you forget to take a dose, don't worry, just take your next dose when it is due. Do not take two doses together to make up for the forgotten dose.

  • Try to keep your regular appointments with your doctor. This is so your doctor can check on your progress. You will need to have regular blood tests during your treatment with gemfibrozil to check that your blood and liver stay healthy.

  • Your doctor will give you advice about eating a healthy diet, avoiding drinking too much alcohol, reducing the amount of salt in your diet, stopping smoking, and taking regular exercise. Following this advice will also help you to reduce your risk of developing heart and blood vessel disease.

  • If you buy any medicines, check with a pharmacist that they are safe to take with gemfibrozil. This is because gemfibrozil has the potential to interact with other medicines.

  • Treatment with gemfibrozil is usually long-term unless you experience an adverse effect. Continue to take the tablets/capsules unless you are advised otherwise by your doctor.

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Along with their useful effects, most medicines can cause unwanted side-effects although not everyone experiences them. The table below contains some of the most common ones associated with gemfibrozil. The best place to find a full list of the side-effects which can be associated with your medicine, is from the manufacturer's printed information leaflet supplied with the medicine. Alternatively, you can find an example of a manufacturer's information leaflet in the reference section below. Speak with your doctor or pharmacist if any of the following continue or become troublesome.

Very common

gemfibrozil side-effects (these affect more than 1 in 10 people)


Was kann ich tun, wenn ich das erlebe?

Verdauungsstörungen

Halten Sie sich an einfache Speisen - vermeiden Sie fettige oder scharfe Mahlzeiten

Common

gemfibrozil side-effects (these affect fewer than 1 in 10 people)

Was kann ich tun, wenn ich das erlebe?

Tummy (abdominal) pain, wind, feeling sick (nausea)

Halten Sie sich an einfache Speisen - vermeiden Sie fettige oder scharfe Mahlzeiten

Kopfschmerzen

Trinken Sie viel Wasser und bitten Sie Ihren Apotheker, ein geeignetes Schmerzmittel zu empfehlen. Wenn die Kopfschmerzen anhalten, sprechen Sie mit Ihrem Arzt

Durchfall

Trinken Sie viel Wasser, um verlorene Flüssigkeiten zu ersetzen

Verstopfung

Versuchen Sie, sich ausgewogen zu ernähren und jeden Tag mehrere Gläser Wasser zu trinken

A sense of spinning (vertigo), feeling tired

Fahren Sie nicht und benutzen Sie keine Werkzeuge oder Maschinen, während Sie beeinträchtigt sind

Hautausschlag

If this becomes severe or troublesome, speak with your doctor

Wichtig: if you develop any muscle aches or pains, particularly in your legs, you should tell your doctor about it. This is a rare, but potentially serious, side-effect of treatment.

Wenn Sie andere Symptome bemerken, die Ihrer Meinung nach auf das Medikament zurückzuführen sind, sprechen Sie mit Ihrem Arzt oder Apotheker für weitere Ratschläge.

  • Bewahren Sie alle Medikamente außerhalb der Reichweite und Sicht von Kindern auf.

  • An einem kühlen, trockenen Ort aufbewahren, fern von direkter Hitze und Licht.

Wichtige Informationen über alle Medikamente

Nehmen Sie niemals mehr als die vorgeschriebene Dosis ein. Wenn Sie vermuten, dass Sie oder jemand anderes eine Überdosis dieses Medikaments eingenommen haben könnte, gehen Sie in die Notaufnahme Ihres örtlichen Krankenhauses. Nehmen Sie den Behälter mit, auch wenn er leer ist.

Dieses Medikament ist für Sie. Geben Sie es niemals an andere Personen weiter, auch wenn deren Zustand ähnlich erscheint wie Ihrer.

Wenn Sie sich einer Operation oder Zahnbehandlung unterziehen, informieren Sie die Person, die die Behandlung durchführt, welche Medikamente Sie einnehmen.

Bewahren Sie keine abgelaufenen oder unerwünschten Medikamente auf. Bringen Sie sie zu Ihrer örtlichen Apotheke, die sie für Sie entsorgt.

Wenn Sie Fragen zu diesem Medikament haben, fragen Sie Ihren Apotheker.

Berichten Sie Nebenwirkungen eines Medikaments oder Impfstoffs

Wenn Sie Nebenwirkungen bemerken, können Sie diese online über die Yellow Card website.

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Häufig gestellte Fragen

What is hyperlipidaemia and why is it a concern?

Hyperlipidaemia means that the concentration of fats (lipids), such as cholesterol and triglycerides, in your blood is too high. Although high lipid levels don't make you feel unwell, they can lead to health problems. Excess fat can build up on the walls of your blood vessels, forming small fatty lumps. These can reduce blood flow and increase your risk of heart disease, stroke, and other circulation issues if left untreated.

How does gemfibrozil help manage high lipid levels?

Gemfibrozil helps to lower the levels of fats in your blood. By doing this, it aims to prevent the long-term heart and circulation problems that can arise from high lipid levels. Your doctor will likely prescribe it if you have high triglyceride levels, or if other medicines like statins are not suitable for you.

Is it important to make lifestyle changes while taking gemfibrozil?

Yes, your treatment with gemfibrozil will be more effective if you also follow healthy lifestyle advice from your doctor. This includes eating a healthy diet, avoiding excessive alcohol, reducing salt intake, stopping smoking, and getting regular exercise. These changes further help reduce your risk of heart and blood vessel disease.

How long will I need to take gemfibrozil?

Treatment with gemfibrozil is usually long-term. You should continue to take the tablets or capsules regularly unless your doctor advises you otherwise or if you experience any adverse effects that require stopping the medication.

What should I do if I forget to take a dose of gemfibrozil?

If you forget to take a dose, don't worry. Simply take your next dose when it is due. You should not take two doses together to make up for the one you missed.

Can I take other medicines, including over-the-counter ones, with gemfibrozil?

Before starting gemfibrozil, it's important to tell your doctor about all other medicines you are taking, including those bought without a prescription, as well as herbal and complementary medicines. Also, if you buy any new medicines while on gemfibrozil, check with a pharmacist to ensure they are safe to take together, as gemfibrozil can interact with other medications.

What are the common side effects of gemfibrozil and what can I do about them?

Common side effects can include indigestion, tummy pain, wind, nausea, headache, diarrhoea, constipation, a sense of spinning (vertigo), tiredness, and skin rash. For indigestion, tummy pain, wind, and nausea, stick to simple foods and avoid fatty or spicy meals. For headaches, drink plenty of water. For diarrhoea, drink plenty of water to replace lost fluids, and for constipation, eat a well-balanced diet and drink several glasses of water. If you experience vertigo or tiredness, avoid driving or using tools/machines. If a skin rash becomes severe, speak to your doctor. Importantly, tell your doctor about any muscle aches or pains, especially in your legs, as this is a rare but potentially serious side effect.

Why do I need regular blood tests while taking gemfibrozil?

You will need regular blood tests throughout your treatment with gemfibrozil. These tests allow your doctor to monitor your progress and ensure that your blood and liver remain healthy while you are taking the medicine.

Weiterführende Literatur und Referenzen

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About the authorView full bio

Author image

Michael Stewart, MRPharmS

Manager für die Überprüfung von Beipackzetteln – Auftragnehmer, Apotheker

BPharm (Hons), MRPharmS

Michael ist ein Gemeindapotheker, der in den Midlands und South Yorkshire praktiziert und über mehr als 20 Jahre Erfahrung in der Beratung zu Medikamenten und medizinischen Bedingungen verfügt. Er hat einen starken Hintergrund in der Gesundheitsausbildung, da er Schulungskurse für Apothekenteams und Mitarbeiter von Pflegeeinrichtungen, einschließlich Krankenschwestern, erstellt und durchgeführt hat. Er hat auch zu Apothekenbeiräten für das Management von geringfügigen Erkrankungen in der Gemeinschaft beigetragen.

About the reviewer

Author image

Sid Dajani

Sultan Dajani qualified at the London School of Pharmacy in 1994 and became the youngest elected member of the Royal Pharmaceutical Society council since its founding in 1842.

Artikelverlauf

Die Informationen auf dieser Seite wurden von qualifizierten Klinikern verfasst und begutachtet.

  • Nächste Überprüfung fällig: 11. Juli 2027
  • 12 Jan 2023 | Neueste Version

    Zuletzt aktualisiert von

    Michael Stewart, MRPharmS

    Begutachtet von

    Sid Dajani
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