Sildenafil bei pulmonaler arterieller Hypertonie

About sildenafil for pulmonary arterial hypertension

Pulmonary arterial hypertension (PAH) is a condition where there is too high a blood pressure in the arteries which supply blood to your lungs from your heart. The arteries become narrowed so your heart has to work harder to pump blood to your lungs.

Sildenafil relaxes the muscles in the walls of the arteries, allowing the blood vessels to become wider. This reduces the pressure in the arteries and allows blood to flow more easily through them. In turn, this increases the supply of blood to your lungs and improves your ability to do physical activities. Sildenafil will be prescribed for you by a doctor who is a specialist.

Another brand of sildenafil tablets called Viagra® is used by men for a completely different condition called erectile dysfunction. There is another medicine leaflet called Sildenafil bei erektiler Dysfunktion which gives more information about this.

Before taking sildenafil for PAH

Einige Medikamente sind für Menschen mit bestimmten Erkrankungen nicht geeignet, und manchmal darf ein Medikament nur mit besonderer Vorsicht angewendet werden. Aus diesen Gründen ist es wichtig, dass Ihr Arzt Bescheid weiß, bevor Sie mit der Einnahme von Sildenafil beginnen:

• Wenn Sie schwanger sind oder stillen.

• If you have any other heart or blood vessel disease.

• Wenn Sie niedrigen Blutdruck haben.

• Wenn Sie eine Erkrankung haben, die Blutungen verursacht, wie z.B. ein Magengeschwür.

• Wenn Sie eine Augenerkrankung hatten, die zu Sehverlust geführt hat.

• Wenn Sie Probleme mit der Funktionsweise Ihrer Leber haben oder Probleme mit der Funktionsweise Ihrer Nieren.

• Wenn Sie einen Schlaganfall oder Herzinfarkt hatten.

• Wenn Sie eine Krankheit, Verletzung oder Deformität Ihres Penis haben.

• Wenn Sie Sichelzellenanämie haben.

• Wenn Sie jemals Knochenmarkkrebs oder Leukämie hatten.

• If you are taking or using any other medicines. This includes any medicines you are taking which are available to buy without a prescription, as well as herbal and complementary medicines. It is important that your doctor knows if you are using a nitrate medicine to treat angina pain, or if you are using a recreational drug called a 'popper'.

• Wenn Sie jemals eine allergische Reaktion auf ein Medikament hatten.

How to take sildenafil tablets for PAH

• Before you start the treatment, read the manufacturer's printed information leaflet from inside the pack, along with any information you have been given by your hospital. The manufacturer's leaflet will give you more information about Revatio® and will provide you with a full list of the side-effects which you may experience from taking it.

• Take sildenafil exactly as your doctor tells you to. The usual dose for adults is one 20 mg tablet three times daily (6-8 hours apart), but your doctor will tell you what dose is right for you. Try to take your doses at the same times of day each day, as this will help you to remember to take the tablets regularly.

• Swallow the tablet with a drink of water. You can take sildenafil either before or after food.

• Wenn Sie eine Dosis vergessen haben, nehmen Sie sie so bald wie möglich ein. Versuchen Sie, die richtige Anzahl an Dosen pro Tag einzunehmen, aber nehmen Sie nicht zwei Dosen gleichzeitig ein, um eine vergessene Dosis auszugleichen.

• If you are giving sildenafil liquid medicine to your child, shake the bottle well before you measure out the dose. Use the oral dose syringe provided in the pack to give the correct dose. The mixture will have been made up freshly by your pharmacy when it is supplied to you. Store the bottle in a refrigerator. It will keep for four weeks.

Instructions for using the dosing syringe with Revatio® oral suspension

1. Shake the bottle well for at least 10 seconds.

2. Remove the bottle cap and make sure the plastic adaptor is fitted into the top of the open bottle.

3. Insert the tip of the dosing syringe into the adapter.

4. Drehen Sie die Flasche (mit der daran angeschlossenen Spritze) auf den Kopf.

5. Ziehen Sie den Kolben der Spritze vorsichtig heraus, damit die Lösung die Spritze bis zur Markierung füllt, die Ihrer Dosis entspricht.

6. Turn the bottle the correct way up again and remove the syringe from the bottle.

7. Put the tip of the syringe into your (or your child's) mouth and gently push the plunger so that the liquid is released.

Das Beste aus Ihrer Behandlung herausholen

• Try to keep your regular appointments with your doctor so your progress can be checked.

• Do not drink grapefruit juice while you are on sildenafil. This is because a chemical in grapefruit juice is thought to increase the amount of sildenafil in your bloodstream. This makes side-effects more likely.

• Each time you collect a new supply of tablets from your pharmacy, check to make sure that the tablets look to be the same as you have had before. There is another brand of sildenafil tablets available for a different condition and these are not suitable for you. If you are unsure about your supply, please ask your pharmacist to check the tablets for you.

• Treatment with sildenafil for PAH is usually long-term. Continue to take the tablets unless you are advised otherwise by your doctor. Stopping treatment suddenly can cause problems, so if it becomes necessary for you to stop taking sildenafil, your doctor may want you to reduce your dose gradually.

• Women with pulmonary hypertension should avoid becoming pregnant as pregnancy can lead to serious worsening of your condition. Women of childbearing potential must use effective contraception during treatment with sildenafil. Speak with your doctor about which contraceptive methods are suitable for you.

• If you are due to have an operation or some other medical treatment, it is important that you tell the person carrying out the treatment that you are on sildenafil.

• If you buy any medicines 'over the counter', always check with a pharmacist that they are suitable for you to take with sildenafil.

Kann Sildenafil Probleme verursachen?

Zusätzlich zu ihren nützlichen Wirkungen können die meisten Medikamente unerwünschte Nebenwirkungen verursachen, obwohl nicht jeder sie erlebt. Die folgende Tabelle enthält einige der häufigsten Nebenwirkungen, die mit Sildenafil in Verbindung gebracht werden. Eine vollständige Liste finden Sie im Beipackzettel des Herstellers, der Ihrem Medikament beiliegt. Die unerwünschten Wirkungen bessern sich oft, wenn sich Ihr Körper an das neue Medikament gewöhnt, aber sprechen Sie mit Ihrem Arzt oder Apotheker, wenn eine der folgenden Nebenwirkungen anhält oder problematisch wird.

If you experience any other symptoms which you think may be due to sildenafil, please speak with your doctor or pharmacist for further advice.

Wie man Sildenafil aufbewahrt

• Bewahren Sie alle Medikamente außerhalb der Reichweite und Sicht von Kindern auf.

• An einem kühlen, trockenen Ort aufbewahren, fern von direkter Hitze und Licht.

• If you have been given liquid medicine, this will have been made up by the pharmacy and lasts for four weeks stored in a fridge. Make sure you check the expiry date on the bottle and do not use it after this date.

Wichtige Informationen über alle Medikamente