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Chlortalidon-Tabletten

Hylaton

Chlortalidone is a 'water tablet' (a diuretic).

It is best taken in the morning, with breakfast.

Any side-effects are usually mild, but may include feeling sick (nausea) or dizziness.

At a glance

  • Chlortalidone is a 'water tablet' (diuretic) that helps your kidneys pass out more urine.

  • It is used to treat high blood pressure, fluid retention, heart failure, and diabetes insipidus.

  • Take your dose in the morning, ideally after food, to reduce stomach upset and avoid night-time toilet trips.

  • Do not stop taking chlortalidone for high blood pressure without speaking to your doctor.

  • Be aware of dehydration symptoms like constant thirst or dry mouth.

  • Your doctor will monitor your blood salt levels with regular blood tests.

  • Common side-effects include loss of appetite, stomach upset, and dizziness.

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About chlortalidone

Art des Medikaments

A thiazide-related diuretic

Verwendet für

High blood pressure; fluid retention; heart failure; diabetes insipidus

Auch genannt

Chlorthalidone (in US); Hylaton® Combination brands are: Tenoret® (chlortalidone with Atenolol); Tenoretic® (chlortalidone with atenolol);

Verfügbar als

Tabletten

Chlortalidone belongs to a group of medicines called thiazide-related diuretics. A diuretic is a medicine which increases the amount of urine that you pass out from your kidneys. They are often referred to as 'water tablets'. Diuretics are a common treatment for hoher Blutdruck (Hypertonie). They are also used to clear excess fluid in some liver and kidney conditions where the body retains more fluid than it needs. Chlortalidone is also useful in people who have Herzinsuffizienz. Heart failure is a condition where the heart does not function as well as it should.

Diuretics like chlortalidone work by interfering with the movement of salt and water across certain cells in your kidneys. The effect of this is to make your kidneys pass out more urine. The removal of fluid reduces your blood pressure and helps reduce the work your heart has to do. Chlortalidone tends to have only a weak action on the kidneys, so it is unlikely you will notice a great increase in urine.

Chlortalidone may also be given alongside other medicines used to treat fluid retention and/or hypertension. When it is used like this, you may be prescribed a combination tablet. Combination tablets help to reduce the total number of tablets you need to take each day.

Chlortalidone tablets may also be of benefit to people with diabetes insipidus. This is a condition where a person produces large amounts of dilute urine and is constantly thirsty. How chlortalidone works in diabetes insipidus is not fully understood.

Some medicines are not suitable for people with certain conditions, and sometimes a medicine may only be used if extra care is taken. For these reasons, before you start taking chlortalidone it is important that your doctor knows:

  • Wenn Sie schwanger sind oder stillen.

  • If you have kidney or liver problems.

  • If you have gout, diabetes, or an inflammatory condition called lupus or SLE (systemic lupus erythematosus). These conditions may be made worse by diuretics.

  • If you have been told by a doctor that you have low sodium or potassium levels in your blood, or high calcium levels in your blood.

  • If you have a problem with your adrenal glands, called Addison-Krankheit.

  • Wenn Sie andere Medikamente einnehmen oder verwenden. Dazu gehören alle Medikamente, die Sie einnehmen und die ohne Rezept erhältlich sind, sowie pflanzliche und ergänzende Medikamente.

  • Wenn Sie jemals eine allergische Reaktion auf ein Medikament hatten.

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  • Before you start this treatment, read the manufacturer's printed information leaflet from inside your pack. The leaflet will give you more information about the tablets and a full list of side-effects which you may experience from taking them.

  • Take chlortalidone exactly as your doctor tells you to. The usual dose is ½-1 tablet daily (25-50 mg), although your dose may be different to this. Your doctor is likely to recommend that you take your dose in the morning. This is so it works during the day and your sleep is not disturbed by needing to get up to make extra trips to the toilet during the night.

  • Although you can take the tablets before or after food, you are recommended to take them after a meal (usually breakfast). This is because the food in your stomach will help to reduce the side-effect of stomach upset.

  • If you forget to take a dose, take it as soon as you remember. However, if it is after 6 pm in the evening, you should skip the forgotten dose and continue as usual the next day. Do not take two doses together to make up for a missed dose.

  • Diuretics like chlortalidone help you to lose water. Occasionally you may lose too much and become dehydrated. Let your doctor know if you feel constantly thirsty, your mouth is dry, or your skin looks and feels dry.

  • Try to keep your regular appointments with your doctor. This is so your doctor can check on your progress. The salt balance in your bloodstream may be upset by chlortalidone and your doctor may want you to have a blood test from time to time to check for this.

  • If you have been prescribed chlortalidone for high blood pressure, your treatment is likely to be long-term. Although many people with high blood pressure do not feel unwell, if left untreated, high blood pressure can harm your heart and damage your blood vessels. This damage may later result in a heart attack, stroke, or kidney problems. It is important that you continue to take chlortalidone regularly to help reduce the risk of this.

  • You may also be given some lifestyle or dietary advice by your doctor, such as stopping smoking, reducing the amount of salt in your diet and taking some regular exercise. Following this advice will help to reduce the risk of damage to your heart and blood vessels.

  • Drinking alcohol while you are on chlortalidone may make you feel dizzy. Ask for your doctor's advice about whether you should avoid alcohol.

  • If you buy any medicines, check with a pharmacist that they are suitable to take alongside chlortalidone.

  • Wenn Sie sich einer Operation oder Zahnbehandlung unterziehen, informieren Sie die Person, die die Behandlung durchführt, welche Medikamente Sie einnehmen.

  • If you have diabetes (diabetes mellitus), chlortalidone may affect your blood sugar (glucose) levels. Test your blood or urine regularly and speak with your doctor if you notice any significant changes.

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Along with their useful effects, most medicines can cause unwanted side-effects although not everyone experiences them. The table below contains some of the most common ones associated with chlortalidone. You will find a full list in the manufacturer's information leaflet supplied with your medicine. The unwanted effects often improve as your body adjusts to the new medicine, but speak with your doctor or pharmacist if any of the following continue or become troublesome.

Common

chlortalidone side-effects

Was kann ich tun, wenn ich das erlebe?

Loss of appetite, mild gastrointestinal effects such as feeling sick (nausea) or stomach upset

This is usually mild, but it may help to take the tablets after food

Feeling dizzy, particularly when you stand up (due to low blood pressure)

Getting up more slowly should help. Do not drive and do not use tools or machines until you feel better

Impotence, itchy skin rash

Wenn eines dieser Probleme auftritt, sprechen Sie mit Ihrem Arzt

Changes in some blood tests

Ihr Arzt wird dies überwachen

Wenn Sie andere Symptome bemerken, die Ihrer Meinung nach auf dieses Medikament zurückzuführen sind, sprechen Sie mit Ihrem Arzt oder Apotheker.

  • Bewahren Sie alle Medikamente außerhalb der Reichweite und Sicht von Kindern auf.

  • An einem kühlen, trockenen Ort aufbewahren, fern von direkter Hitze und Licht.

Wichtige Informationen über alle Medikamente

Nehmen Sie niemals mehr als die vorgeschriebene Dosis ein. Wenn Sie vermuten, dass Sie oder jemand anderes eine Überdosis dieses Medikaments eingenommen haben könnte, gehen Sie in die Notaufnahme Ihres örtlichen Krankenhauses. Nehmen Sie den Behälter mit, auch wenn er leer ist.

Dieses Medikament ist für Sie. Geben Sie es niemals an andere Personen weiter, auch wenn deren Zustand ähnlich erscheint wie Ihrer.

Bewahren Sie keine abgelaufenen oder unerwünschten Medikamente auf. Bringen Sie sie zu Ihrer örtlichen Apotheke, die sie für Sie entsorgt.

Wenn Sie Fragen zu diesem Medikament haben, fragen Sie Ihren Apotheker.

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Häufig gestellte Fragen

What is the main purpose of chlortalidone?

Chlortalidone is a type of 'water tablet' (diuretic) that helps your kidneys pass out more urine. This action helps to reduce your blood pressure, clear excess fluid from your body in conditions like heart failure or certain liver and kidney problems, and can also be beneficial for people with diabetes insipidus.

How does chlortalidone work to reduce fluid and blood pressure?

Chlortalidone works by interfering with how salt and water move across cells in your kidneys. This leads to your kidneys producing more urine, which helps to remove excess fluid from your body. The reduction in fluid then helps to lower your blood pressure and decrease the workload on your heart.

When is the best time of day to take chlortalidone tablets?

It is usually recommended to take your dose of chlortalidone in the morning, ideally after a meal (such as breakfast). Taking it in the morning allows the medicine to work during the day, which helps prevent your sleep from being disturbed by needing to go to the toilet frequently during the night. Taking it after a meal can also help reduce stomach upset.

What should I do if I feel constantly thirsty or have a dry mouth while on chlortalidone?

Chlortalidone helps you lose water, and sometimes you might lose too much and become dehydrated. If you experience constant thirst, a dry mouth, or your skin looks and feels dry, you should let your doctor know.

Can I drink alcohol while taking chlortalidone?

Drinking alcohol when you are taking chlortalidone may cause you to feel dizzy. You should ask your doctor for specific advice on whether you should avoid alcohol while on this medication.

What are some common side-effects of chlortalidone and what can I do about them?

Common side-effects include loss of appetite or mild stomach upset (like nausea), which might be eased by taking the tablets after food. You might also feel dizzy, especially when standing up, so getting up slowly can help; avoid driving or using tools/machines if you feel dizzy. If you experience impotence or an itchy skin rash, and these become troublesome, you should speak with your doctor. Your doctor will monitor for changes in some blood tests.

What is diabetes insipidus and how does chlortalidone help with it?

Diabetes insipidus is a condition where a person produces large amounts of very dilute urine and feels constantly thirsty. Chlortalidone tablets can be beneficial for people with this condition, although the exact way it works to help is not fully understood.

Weiterführende Literatur und Referenzen

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About the authorView full bio

Author image

Michael Stewart, MRPharmS

Manager für die Überprüfung von Beipackzetteln – Auftragnehmer, Apotheker

BPharm (Hons), MRPharmS

Michael ist ein Gemeindapotheker, der in den Midlands und South Yorkshire praktiziert und über mehr als 20 Jahre Erfahrung in der Beratung zu Medikamenten und medizinischen Bedingungen verfügt. Er hat einen starken Hintergrund in der Gesundheitsausbildung, da er Schulungskurse für Apothekenteams und Mitarbeiter von Pflegeeinrichtungen, einschließlich Krankenschwestern, erstellt und durchgeführt hat. Er hat auch zu Apothekenbeiräten für das Management von geringfügigen Erkrankungen in der Gemeinschaft beigetragen.

About the reviewer

Author image

Sid Dajani

Sultan Dajani qualified at the London School of Pharmacy in 1994 and became the youngest elected member of the Royal Pharmaceutical Society council since its founding in 1842.

Artikelverlauf

Die Informationen auf dieser Seite wurden von qualifizierten Klinikern verfasst und begutachtet.

  • Nächste Überprüfung fällig: 27. Sept. 2027
  • 28 Mar 2023 | Neueste Version

    Zuletzt aktualisiert von

    Michael Stewart, MRPharmS

    Begutachtet von

    Sid Dajani
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