Melatonin-Tabletten gegen Schlaflosigkeit
Adaflex, Circadin
Begutachtet von Sid DajaniZuletzt aktualisiert von Michael Stewart, MRPharmSLast updated 30. Aug 2023
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Melatonin is useful in helping to promote sleep in people over the age of 55 years who have difficulty sleeping. It also helps to promote sleep in children with learning difficulties such as Autism Spectrum Disorder (ASD) and ADHD.
Take one 2 mg tablet 1-2 hours before bedtime, with a snack.
Melatonin will make you feel sleepy, so do not drive and do not use tools or machines until this effect has worn off.
At a glance
Melatonin is a sleeping tablet that helps with poor sleep.
It is prescribed for certain adults and children with specific conditions.
Take melatonin exactly as your doctor tells you, usually 1-2 hours before bedtime.
Do not drink alcohol or take it for longer than your doctor advises.
Common side-effects can include feeling tired, headache, or indigestion.
If you have side-effects that worry you, speak to your doctor or pharmacist.
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About melatonin
Art des Medikaments | Hypnotikum (Schlafmittel) |
Verwendet für | Schlechter Schlaf |
Auch genannt | Adaflex®; Ceyesto®; Circadin®; Civasta®; Slenyto®; Syncrodin® |
Verfügbar als | Modified-release tablets, tablets, capsules and oral liquid medicine |
Schlechter Schlaf can mean that you have difficulty getting to sleep, or that you wake up for long periods during the night, or that you wake early, or that you do not feel refreshed in the mornings.
Insomnia is a fairly common condition, but it does not usually last for long. Melatonin is a hormone which occurs naturally in the body and is associated with the control of the body's sleep pattern. As we grow older the amount of naturally occurring melatonin in the body reduces. Taking melatonin adds to the body's natural supply and helps to promote and improve the quality of sleep.
Circadin® and Civasta® tablets are prescribed for people over the age of 55 years who have insomnia, or difficulty sleeping.
Slenyto® tablets are prescribed for poor sleep in children between the ages of 2 years and 18 years with Autism Spectrum Disorder (ASD) or Smith-Magenis syndrome.
Adaflex® and Ceyesto® tablets are prescribed for poor sleep in children aged 6 to 17 years with ADHD. They can also be prescribed for adults who experience jet lag.
Syncrodin® tablets are prescribed for adults who experience jet lag.
Sometimes a doctor may prescribe melatonin for other groups of people with sleeping problems. If this is the case for you, the way you take melatonin and your dose may be different from the information in this leaflet. Follow your doctor's instructions carefully and ask your doctor or pharmacist if you are unsure of anything.
Before taking melatonin
Zurück zum InhaltSome medicines are not suitable for people with certain conditions, and sometimes a medicine may only be used if extra care is taken. For these reasons, before you start taking melatonin it is important that your doctor or pharmacist knows:
Wenn Sie Probleme mit der Funktionsweise Ihrer Leber oder Ihrer Nieren haben.
If you have an autoimmune disease - a condition in which the body is attacked by its own overactive immune system. It includes conditions such as rheumatoide Arthritis, multiple sclerosis, and lupus.
Wenn Sie andere Medikamente einnehmen. Dazu gehören alle Medikamente, die Sie einnehmen und die ohne Rezept erhältlich sind, sowie pflanzliche und ergänzende Medikamente.
Wenn Sie jemals eine allergische Reaktion auf ein Medikament hatten.
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How to take melatonin
Zurück zum InhaltBefore you start the treatment, read the manufacturer's printed information leaflet from inside the pack. It will give you more information about melatonin and will provide you with a full list of the side-effects which you may experience from taking it.
Take melatonin exactly as your doctor tells you to. For adults the dose is usually one 2 mg tablet daily, taken 1-2 hours before bedtime. For children with ASD the usual starting dose is 2 mg taken 30 minutes to one hour before bedtime. Your child's doctor may increase the dose slowly to get a better response.
Take the tablet with a snack or after eating some food. This will help the medicine to work later into the night. Swallow the tablet whole - do not break or crush the tablet because it is designed to release melatonin slowly over a few hours.
If you forget to take a tablet at the usual time but you remember before you go to sleep, take it when you remember. If you do not remember until the following day, just take the next dose as usual. Do not take two doses together to make up for a forgotten dose.
Das Beste aus Ihrer Behandlung herausholen
Zurück zum InhaltDo not take melatonin for longer than your doctor advises. It can be prescribed for up to 13 weeks for adults over 55.
Do not drink alcohol while you are taking melatonin because it will reduce the medicine's effectiveness in helping you to sleep.
Try to keep your regular appointments with your doctor. This is so your progress can be monitored.
There are some general recommendations that may help promote good sleep. Try to reduce the amount of caffeine you drink, especially in the afternoon and evening. Try to avoid eating heavy meals or drinking alcohol before bedtime. Exercise early in the day, rather than in the evening.
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Can melatonin cause problems?
Zurück zum InhaltAlong with their useful effects, most medicines can cause unwanted side-effects but not everyone experiences them. The table below contains some of the side-effects associated with melatonin. Children may be more likely than adults to experience these side-effects. You will find a full list in the manufacturer's information leaflet supplied with your medicine. The unwanted effects often improve as your body adjusts to the new medicine, but speak with your doctor or pharmacist if any of the following continue or become troublesome.
Melatonin side-effects (these affect fewer than 1 in 10 people) | Was kann ich tun, wenn ich das erlebe? |
Feeling tired or sleepy | Do not drive and do not use tools or machines until these effects have worn off |
Kopfschmerzen | Trinken Sie viel Wasser und bitten Sie einen Apotheker, ein geeignetes Schmerzmittel zu empfehlen. Wenn die Kopfschmerzen anhalten, informieren Sie Ihren Arzt |
Indigestion, feeling sick (nausea), stomach ache | Halten Sie sich an einfache Speisen - vermeiden Sie reichhaltige oder scharfe Mahlzeiten |
Feeling irritable or restless, mood swings, dry mouth, abnormal dreams, night sweats, dry or itchy skin, pains in the arms or legs | Wenn eines dieser Probleme auftritt, sprechen Sie mit Ihrem Arzt |
If you experience any other symptoms which you think may be due to the tablets, speak with your doctor or pharmacist for further advice. Children with ASD may be more likely to experience mood swings, irritability or aggression when taking melatonin.
How to store melatonin
Zurück zum InhaltBewahren Sie alle Medikamente außerhalb der Reichweite und Sicht von Kindern auf.
An einem kühlen, trockenen Ort aufbewahren, fern von direkter Hitze und Licht.
Wichtige Informationen über alle Medikamente
Zurück zum InhaltWichtige Informationen über alle Medikamente
Nehmen Sie niemals mehr als die vorgeschriebene Dosis ein. Wenn Sie vermuten, dass Sie oder jemand anderes eine Überdosis dieses Medikaments eingenommen hat, gehen Sie sofort in die Notaufnahme Ihres örtlichen Krankenhauses. Nehmen Sie den Behälter mit, auch wenn er leer ist.
Dieses Medikament ist für Sie. Geben Sie es niemals an andere Personen weiter, auch wenn deren Zustand ähnlich erscheint wie Ihrer.
If you are having an operation or dental treatment, always tell the person carrying out the treatment which medicines you are taking.
Wenn Sie Medikamente kaufen, fragen Sie einen Apotheker, ob sie sicher mit Ihren anderen Medikamenten eingenommen werden können.
Bewahren Sie keine abgelaufenen oder unerwünschten Medikamente auf. Bringen Sie sie zu Ihrer örtlichen Apotheke, die sie für Sie entsorgt.
Wenn Sie Fragen zu diesem Medikament haben, fragen Sie Ihren Apotheker.
Berichten Sie Nebenwirkungen eines Medikaments oder Impfstoffs
Wenn Sie Nebenwirkungen bemerken, können Sie diese online über die Yellow Card website.

Unsicher beim Mischen von Medikamenten?
Überprüfen Sie mögliche Wechselwirkungen zwischen Medikamenten, Nahrungsergänzungsmitteln und Lebensmitteln, bevor Sie sie zusammen einnehmen.
Häufig gestellte Fragen
What is insomnia and how does melatonin help?
Insomnia is a common condition where you have difficulty getting to sleep, wake up for long periods during the night, wake early, or don't feel refreshed in the mornings. Melatonin is a natural hormone in your body that controls your sleep pattern. As you get older, your natural melatonin supply decreases. Taking melatonin supplements adds to your body's supply, which then helps promote and improve the quality of your sleep.
Are there common daily habits that I should avoid or adopt to help melatonin work better?
Yes, there are a few habits that can help. You should avoid drinking alcohol while taking melatonin as it reduces its effectiveness. It's also recommended to reduce caffeine, especially in the afternoon and evening, and avoid heavy meals before bedtime. Exercising earlier in the day rather than in the evening can also be beneficial.
How long can I expect to be on melatonin treatment?
You should not take melatonin for longer than your doctor advises. For adults over 55, it can be prescribed for up to 13 weeks.
When should I take my melatonin tablet if I have forgotten a dose?
If you forget to take your tablet at the usual time but remember before you go to sleep, take it then. If you don't remember until the following day, just take your next dose as usual. Do not take two doses together to make up for a forgotten dose.
What are some common side effects of melatonin and how can I manage them?
Common side-effects, affecting fewer than 1 in 10 people, include feeling tired or sleepy, headache, indigestion, feeling sick, or stomach ache. If you feel tired or sleepy, avoid driving or using tools/machines. For headaches, drink water and consider a painkiller, and if they persist, tell your doctor. For indigestion or feeling sick, stick to simple foods and avoid rich or spicy meals. Children, especially with ASD, might experience mood swings, irritability, or aggression.
Can children take melatonin, and for what conditions?
Yes, children can take melatonin. Slenyto® tablets are prescribed for poor sleep in children aged 2-18 years with Autism Spectrum Disorder (ASD) or Smith-Magenis syndrome. Adaflex® and Ceyesto® tablets are prescribed for poor sleep in children aged 6-17 years with ADHD. The dose and how it's taken may differ, so always follow your doctor's instructions.
I'm having an operation soon. Should I tell my surgeon or dentist about taking melatonin?
Yes, it is important to always tell the person carrying out any operation or dental treatment which medicines you are taking, including melatonin.
Weiterführende Literatur und Referenzen
- Manufacturer's PIL, Circadin® 2 mg prolonged-release Tablets; Flynn Pharma Ltd, The electronic Medicines Compendium. Dated October 2021.
- Manufacturer's PIL, Slenyto® 1 mg and 5 mg prolonged release tablets; Flynn Pharma Ltd, The electronic Medicines Compendium. Dated October 2021.
- Medikamente Komplett BNF 89. Ausgabe; Britische Ärztevereinigung und Königliche Pharmazeutische Gesellschaft von Großbritannien, London.
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About the authorView full bio

Michael Stewart, MRPharmS
Manager für die Überprüfung von Beipackzetteln – Auftragnehmer, Apotheker
BPharm (Hons), MRPharmS
Michael ist ein Gemeindapotheker, der in den Midlands und South Yorkshire praktiziert und über mehr als 20 Jahre Erfahrung in der Beratung zu Medikamenten und medizinischen Bedingungen verfügt. Er hat einen starken Hintergrund in der Gesundheitsausbildung, da er Schulungskurse für Apothekenteams und Mitarbeiter von Pflegeeinrichtungen, einschließlich Krankenschwestern, erstellt und durchgeführt hat. Er hat auch zu Apothekenbeiräten für das Management von geringfügigen Erkrankungen in der Gemeinschaft beigetragen.
About the reviewer

Sid Dajani
Sultan Dajani qualified at the London School of Pharmacy in 1994 and became the youngest elected member of the Royal Pharmaceutical Society council since its founding in 1842.
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