Dexamfetamine for narcolepsy and ADHD

About dexamfetamine

Narcolepsy is a long-term problem that affects your sleep. You feel excessively tired during the daytime but have disturbed sleep during the night. You can also have sleep attacks where you fall asleep at inappropriate times during the day without any warning. Although there is no cure, medicines can help to control the symptoms. Dexamfetamine works by stimulating the central nervous system to increase your alertness and reduce excessive sleepiness during the day. You can, however, develop tolerance to dexamfetamine, so other medicines for narcolepsy (such as modafinil) are often preferred.

Dexamfetamine is also sometimes used by specialists to treat children with attention deficit hyperactivity disorder (ADHD). ADHD is a fairly common condition that mainly affects a person's behaviour. People with ADHD show persistent restlessness, impulsiveness and/or inattention. Help is given to understand your emotions and behaviours but where this is insufficient, medicines may be prescribed. Other medicines for ADHD are often preferred but where these are unsuccessful, dexamfetamine can be helpful.

Before taking dexamfetamine

Some medicines are not suitable for people with certain conditions, and sometimes a medicine may only be used if extra care is taken. For these reasons, before you (or a child in your care) start taking dexamfetamine it is important that your doctor knows:

• Wenn Sie schwanger sind, ein Kind erwarten oder stillen.

• If you have a heart condition, or any problems with your blood vessels.

• Wenn Sie Probleme mit der Funktionsweise Ihrer Nieren haben.

• If you have an overactive thyroid gland (hyperthyroidism).

• Wenn Sie unter hohem Blutdruck leiden.

• If you have had a mental health problem - for example, psychosis or bipolar disorder.

• Wenn Sie Epilepsie haben.

• If you have ever had any uncontrollable movements such as a nervous tic, or if you have a condition called Tourette's syndrome.

• If you have raised pressure in your eyes (glaucoma).

• If you have ever had a problem with drug or alcohol misuse.

• If you have an eating disorder such as anorexia nervosa.

• Wenn Sie eine seltene vererbte Blutkrankheit namens Porphyrie haben.

• Wenn Sie andere Arzneimittel einnehmen. Dazu gehören alle Arzneimittel, die ohne Rezept erhältlich sind, sowie pflanzliche und ergänzende Arzneimittel.

• Wenn Sie schon einmal eine allergische Reaktion auf ein Arzneimittel hatten.

How to take dexamfetamine

• Before starting this treatment, read the manufacturer's printed information leaflet from inside the pack. The leaflet will give you more information about dexamfetamine and a full list of side-effects from taking it.

• Make sure you take dexamfetamine exactly as your doctor tells you to. Your doctor or pharmacist will tell you how many tablets to take and when to take them. It is usual to take 2-4 doses of dexamfetamine each day. Your dose will be on the label of the pack to remind you.

• When starting your treatment your doctor may give you a small dose and then gradually increase it. This allows your doctor to make sure that you have the dose that helps your condition but avoids unwanted side-effects.

• It is not important whether you take dexamfetamine before or after food, but try to remember to take your doses at the same times of day, each day. This will help you avoid missing doses. If you do forget to take a dose, do not worry, just remember to take the next dose when it is due. Do not take two doses together to make up for a forgotten dose.

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• Keep the regular appointments with your doctor so your progress can be monitored. Your doctor will want to check to ensure that the treatment is helping. There may also be tests that your doctor wants you to have - this is especially the case for children taking dexamfetamine.

• Do not drink alcohol while you are on dexamfetamine. Alcohol will increase the risk of side-effects so it is not recommended.

• Before you buy any medicines, check with a pharmacist that they are safe to take with dexamfetamine.

• If you are a driver, please be aware that dexamfetamine is likely to affect your reactions and ability to drive. It is an offence to drive while your reactions are impaired. Even if your driving ability is not impaired, should you drive, you are advised to carry with you some evidence that the medicine has been prescribed for you - a repeat prescription form or a patient information leaflet from the pack is generally considered suitable.

• If you are due to have an operation, it is important that you tell the person carrying out the treatment that you are taking dexamfetamine.

• Taking dexamfetamine can lead to your body becoming dependent on it. Your doctor will discuss this with you before you start treatment.

• Do not stop taking dexamfetamine unless your doctor tells you to do so. This is because stopping it suddenly can cause problems and your doctor is likely to recommend that your dose should be reduced gradually.

Additional information if dexamfetamine is for narcolepsy

• Have a regular sleep routine. Aim to get around eight hours of sleep at night if possible. You should try to go to sleep and get up at about the same times each day. Some people find that scheduled naps during the day can help to reduce their daytime sleepiness.

• In the UK, you are required to let the Driver and Vehicle Licensing Authority (DVLA) know if you are diagnosed with narcolepsy. You should stop driving straightaway, and not drive again until you are permitted to do so by the DVLA.

• You should try to avoid heavy meals, as these can make you sleepy. Doing regular exercise may be of benefit and may help your symptoms.

• You may find it helpful to tell close friends and work colleagues about your condition. This will help them to understand your symptoms, and there may be help that they can give you, such as help with working schedules.

Additional information if dexamfetamine is for ADHD

• There are treatment programmes that will be recommended for you and/or your child. These will provide you with strategies to improve behaviour and reduce any long-term impact.

• From time to time your doctor will assess the treatment to make sure it is still required. This may involve stopping dexamfetamine for a short while.

• There is a small amount of evidence to show that a change in diet may help some people with ADHD. If you think that diet may be a factor for you or your child, discuss this with your doctor to see if speaking with a dietician might be of benefit.

Can dexamfetamine cause problems?

Along with their useful effects, all medicines can cause unwanted side-effects although not everyone experiences them. The table below lists some of the most common ones associated with dexamfetamine. You will find a full list in the manufacturer's information leaflet supplied with your medicine. The unwanted effects often improve over the first few days of taking a new medicine, but speak with your doctor or pharmacist if any of the following side-effects continue or become troublesome.

Wenn Sie andere Symptome haben, von denen Sie glauben, dass sie auf dieses Arzneimittel zurückzuführen sind, sprechen Sie mit Ihrem Arzt oder Apotheker.

How to store dexamfetamine

• Bewahren Sie alle Arzneimittel außerhalb der Reichweite und Sichtweite von Kindern auf.

• An einem kühlen, trockenen Ort aufbewahren, vor direkter Hitze und Licht schützen.

• If you are using the oral solution, you should safely dispose of any remaining liquid once the bottle has been open for 30 days. Make a note of the date when you open the bottle.

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