Olanzapin
Zalasta, Zyprexa
Begutachtet von Sid DajaniZuletzt aktualisiert von Michael Stewart, MRPharmSZuletzt aktualisiert 5. Aug 2024
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Olanzapine belongs to a group of medicines called antipsychotics. It is taken once daily.
Keep your regular appointments with your doctor. This is so your progress can be checked.
The most common side-effects include feeling sleepy or dizzy, and increased weight.
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About Olanzapin
Art des Medikaments | An antipsychotic medicine |
Verwendet für | Easing the symptoms of schizophrenia and mania; preventing high mood swings in bipolar disorder |
Auch genannt | Zalasta®; Zyprexa® |
Verfügbar als | Tablets, and melt-in-the-mouth (orodispersible) tablets |
Olanzapine belongs to a group of medicines called antipsychotics. It may have been prescribed for you to relieve the symptoms of Schizophrenie, or alternatively, it may have been prescribed for the treatment and/or prevention of high mood swings (mania). In both of these conditions, olanzapine works on the balance of chemical substances in your brain.
Maintenance doses of olanzapine can also be given to people with schizophrenia by depot injection. There is a separate medicine leaflet providing more information about this, called Olanzapin-Depotinjektion.
Before taking olanzapine
Zurück zum InhaltSome medicines are not suitable for people with certain conditions, and sometimes a medicine may only be used if extra care is taken. For these reasons, before you start taking olanzapine it is important that your doctor knows:
Wenn Sie schwanger sind oder stillen.
If you have a heart condition or blood vessel disease.
If you have liver, kidney, or prostate problems.
If you have any problems with your breathing.
If you are very constipated or think you may have a blockage in your bowel.
If you have any of the following: epilepsy, diabetes (diabetes mellitus), depression, Parkinson's disease, raised pressure in your eye (glaucoma) or a condition which causes muscle weakness, called myasthenia gravis.
If you have ever had yellowing of your skin or of the whites of your eyes (jaundice).
If you have a blood or bone marrow disorder.
If you have a tumour on your adrenal gland (a condition called phaeochromocytoma).
If you have had an allergic reaction to a medicine.
Wenn Sie andere Medikamente einnehmen oder verwenden. Dazu gehören alle Medikamente, die Sie einnehmen und die ohne Rezept erhältlich sind, sowie pflanzliche und ergänzende Medikamente.
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How to take olanzapine
Zurück zum InhaltBefore you start the treatment, read the manufacturer's printed information leaflet from inside the pack. It will give you more information about olanzapine and it will also provide you with a full list of the side-effects which you may experience from taking it.
Your dose will be adjusted to suit your condition, so take olanzapine tablets exactly as your doctor tells you to. It is usual to be prescribed one dose of olanzapine to take each day. Your dose will be printed on the label of your pack to remind you about what the doctor said to you.
You can take olanzapine tablets either before or after meals.
Try to get into the habit of taking your dose at the same time of day each day, as this will help you to remember to take it. If you do forget to take a dose, take it as soon as you remember. If you do not remember until the following day then skip the missed dose but remember to take the dose that is due on that day. Do not take two doses at the same time to make up for a forgotten dose.
If you have been given orodispersible tablets (e.g Zyprexa® Velotabs) - these are tablets which dissolve in your mouth - place the tablet on your tongue and allow it to dissolve. Alternatively, if you prefer, you can take the orodispersible tablet stirred into a small glassful of any of the following drinks: water, orange or apple juice, milk or coffee.
Das Beste aus Ihrer Behandlung herausholen
Zurück zum InhaltYour treatment will require careful monitoring to make sure that you get the best possible benefit from olanzapine. Keep your regular doctor's appointments so that your progress can be checked. You will need to have some tests from time to time.
Treatment with olanzapine is usually long-term unless you experience an adverse effect. Keep taking it unless your doctor tells you otherwise. Stopping olanzapine suddenly can cause problems, so your doctor may want you to reduce your dose gradually if this becomes necessary.
If you drink alcohol, ask your doctor for advice. Alcohol increases the risk of side-effects from olanzapine so it is best avoided.
If you have diabetes you may need to check your blood glucose more frequently, as olanzapine may affect the levels of sugar in your blood. Your doctor will advise you about this.
Some medicines similar to olanzapine can cause the skin to become more sensitive to sunlight than normal. It may be advisable to use a sunscreen in bright sunlight until you know how your skin reacts.
Smoking may affect the amount of olanzapine in your body. Let your doctor know if you either start or stop smoking while you are taking olanzapine.
A small number of people taking medicines for mood disorders can have thoughts about harming themselves or ending their lives, particularly when a new medicine is started. It is very important that you tell your doctor about this if it happens to you.
If you are due to have any medical or dental treatment, tell the person carrying out the treatment which medicines you are taking. This is important because olanzapine may interfere with any anaesthetic you receive.
If you buy or take any 'over-the-counter' medicines or herbal remedies, please check with a pharmacist that they are suitable for you to take with olanzapine.
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Can olanzapine cause problems?
Zurück zum InhaltAlong with their useful effects, most medicines can cause unwanted side-effects although not everyone experiences them. The table below contains some of the most common ones associated with olanzapine. You will find a full list in the manufacturer's information leaflet supplied with your medicine. The unwanted effects often improve as your body adjusts to the new medicine, but speak with your doctor or pharmacist if any of the following continue or become troublesome.
Very common olanzapine side-effects (these affect more than 1 in 10 people) | Was kann ich tun, wenn ich das erlebe? |
Feeling sleepy or dizzy | Do not drive and do not use tools or machines |
Increased weight | Eat a well-balanced diet. Speak with a pharmacist if your weight becomes troublesome |
Changes to some blood test results | Your doctor will monitor for these |
Common olanzapine side-effects (these affect fewer than 1 in 10 people) | Was kann ich tun, wenn ich das erlebe? |
Feeling restless or tired | Speak with your doctor about this. Do not drive and do not use tools or machines while affected |
Verstopfung | Drink plenty of water and eat a well-balanced diet |
Trockener Mund | Versuchen Sie, zuckerfreien Kaugummi zu kauen oder zuckerfreie Bonbons zu lutschen |
Unusual or uncontrollable muscle movements | Speak with your doctor about these |
Increased appetite, feeling hot, swollen hands or feet, skin rash, reduced interest in sex, erectile dysfunction, aches and pains | Discuss these with your doctor if any become troublesome |
Wichtig: if you experience symptoms such as muscle stiffness, a very high temperature (fever), feeling confused, a fast heartbeat and sweating, you should contact your doctor immediately. These can be signs of a rare but serious condition known as neuroleptic malignant syndrome.
Wenn Sie andere Symptome bemerken, die Ihrer Meinung nach auf die Tabletten zurückzuführen sein könnten, sprechen Sie bitte mit Ihrem Arzt oder Apotheker für weitere Ratschläge.
How to store olanzapine
Zurück zum InhaltBewahren Sie alle Medikamente außerhalb der Reichweite und Sicht von Kindern auf.
An einem kühlen, trockenen Ort aufbewahren, fern von direkter Hitze und Licht.
Wichtige Informationen über alle Medikamente
Zurück zum InhaltWichtige Informationen über alle Medikamente
Nehmen Sie niemals mehr als die vorgeschriebene Dosis ein. Wenn Sie vermuten, dass Sie oder jemand anderes eine Überdosis dieses Medikaments eingenommen haben könnte, gehen Sie in die Notaufnahme Ihres örtlichen Krankenhauses. Nehmen Sie den Behälter mit, auch wenn er leer ist.
Dieses Medikament ist für Sie. Geben Sie es niemals an andere Personen weiter, auch wenn deren Zustand ähnlich erscheint wie Ihrer.
Bewahren Sie keine abgelaufenen oder unerwünschten Medikamente auf. Bringen Sie sie zu Ihrer örtlichen Apotheke, die sie für Sie entsorgt.
Wenn Sie Fragen zu diesem Medikament haben, fragen Sie Ihren Apotheker.
Berichten Sie Nebenwirkungen eines Medikaments oder Impfstoffs
Wenn Sie Nebenwirkungen bemerken, können Sie diese online über die Yellow Card-Website.

Unsicher beim Mischen von Medikamenten?
Überprüfen Sie mögliche Wechselwirkungen zwischen Medikamenten, Nahrungsergänzungsmitteln und Lebensmitteln, bevor Sie sie zusammen einnehmen.
Weiterführende Lektüre und Referenzen
- Manufacturer's PIL, Zyprexa 2.5 mg, 5 mg, 7.5 mg, 10 mg, 15 mg, 20 mg film-coated tablets; Neon Healthcare Ltd, The electronic Medicines Compendium. Dated December 2023.
- Manufacturer's PIL, Zyprexa Velotab® 5 mg, 10 mg, 15 mg and 20 mg orodispersible Tablets; Neon Healthcare Ltd, The electronic Medicines Compendium. Dated December 2023.
- Medikamente Komplett BNF 89. Ausgabe; Britische Ärztevereinigung und Königliche Pharmazeutische Gesellschaft von Großbritannien, London.
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Artikelverlauf
Die Informationen auf dieser Seite wurden von qualifizierten Klinikern verfasst und begutachtet.
Next review due: 1 Aug 2027
5. Aug 2024 | Neueste Version

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