Co-Cyprindiol-Tabletten
Clairette, Dianette
Begutachtet von Sid DajaniZuletzt aktualisiert von Michael Stewart, MRPharmSZuletzt aktualisiert 4. Dez. 2024
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Co-cyprindiol tablets are prescribed for women with certain skin conditions when contraception is also required.
Carefully read and follow the printed information leaflet from inside the pack.
Auf einen Blick
Co-cyprindiol is a hormone treatment used for severe acne or excessive hair growth (hirsutism) in women.
It is prescribed when other treatments for acne have not been effective.
It works by reducing the amount of androgen hormones in the body.
Take one tablet daily for 21 days, then have seven tablet-free days.
It also acts as an oral contraceptive, but it does not protect against STIs.
Speak to your doctor if you experience any mood changes or are worried about side effects.
Stop taking it and contact your doctor immediately if you have chest pain, sudden breathlessness, leg swelling, severe headache, or yellow skin/eyes.
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About co-cyprindiol
Art des Medikaments | A hormone treatment |
Verwendet für | Severe acne or hirsutism in women |
Auch genannt | Clairette®; Dianette® |
Verfügbar als | Tabletten |
Co-cyprindiol is prescribed for two different skin conditions in women - Akne und hirsutism.
Acne is a common skin condition which is often treated by skin creams or antibiotic tablets. You will have been prescribed co-cyprindiol for acne if other treatments have not been sufficiently effective for you.
Hirsutism is a condition where dark, thick hair grows in places where it doesn't usually grow in women, such as on the face or chest.
Co-cyprindiol contains two ingredients, ethinylestradiol and cyproterone. Ethinylestradiol is an oestrogen, which is a female sex hormone. Cyproterone is an anti-androgen. Androgens are responsible for stimulating the glands on your skin which produce an oil (sebum) and they also encourage hair growth. Co-cyprindiol works by reducing the amount of androgen you produce, which helps to clear acne and reduces excess hair growth.
Co-cyprindiol is also an oral contraceptive pill. Although it is not prescribed solely for this purpose, it can be helpful if you have one of the skin conditions mentioned above and also wish to take oral contraception.
Before taking co-cyprindiol
Zurück zum InhaltSome medicines are not suitable for people with certain conditions, and sometimes a medicine can only be used if extra care is taken. For these reasons, before you start taking co-cyprindiol it is important that your doctor knows:
If you are breastfeeding, or if you think you could be pregnant.
If you have ever had an unwanted blood clot, or blood vessel problems.
If you have a breast lump, or if you have had breast cancer.
If you have any problems with the way your liver works, or if you have gallstones.
Wenn Sie vaginale Blutungen haben, die nicht Ihre normale monatliche Periode sind.
If you have high blood levels of fats (lipids), or if you have been told you have high blood levels of prolactin.
If you have any of the following conditions: heart disease, migraine, systemic lupus erythematosus (SLE), porphyria, sickle cell disease, or an inflammatory bowel condition.
If you have ever been diagnosed with depression, or if you have had a transient ischaemic attack (called a 'TIA' or 'mini stroke'), or if you have had haemolytic uraemic syndrome.
If during a pregnancy you have had problems such as severe itching and blistering of your skin, jaundice, or any involuntary jerky movements.
Wenn Sie jemals eine allergische Reaktion auf ein Medikament hatten.
If you are taking any other medicines, including those available to buy without a prescription and herbal or complementary medicines. This is important because some medicines may stop combined hormonal contraceptives from working properly.
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How to take co-cyprindiol
Zurück zum InhaltBefore you start the treatment, read the manufacturer's printed information leaflet from inside the pack. It will give you more information about co-cyprindiol, and it will also provide you with a full list of side-effects which you could experience from taking it.
Starting on the first day of your next period, take one tablet daily for 21 days and then have seven days without taking a tablet. Continue to take one tablet daily for 21 days and then have seven pill-free days until your doctor tells you otherwise.
You should take your tablets at the same time of day each day. This is particularly important if you are taking them to prevent pregnancy. If you forget to take a tablet on time, take it as soon as you remember, and then take the next dose at your usual time (even if this means taking two tablets on the same day). If you are more than 12 hours late taking a tablet, your protection against pregnancy could be reduced. In this case, for the following seven days you must either use a barrier method of contraception such as a condom, or avoid sex. If these seven days run beyond the end of your packet of pills, start the next packet straightaway without any tablet-free days. This means you may not have a period until the end of the two packets.
Das Beste aus Ihrer Behandlung herausholen
Zurück zum InhaltTry to keep your regular appointments with your doctor or clinic. This is so your doctor can check on your progress. You will need to have your blood pressure checked from time to time.
If you suspect at any time that you may be pregnant, stop taking co-cyprindiol and see your doctor or pharmacist for a pregnancy test straightaway.
Wichtig: if you have a bout of being sick (vomiting) or diarrhoea, it can reduce the effectiveness of the contraception. If this happens, use a condom if you have sex during the illness and for seven days after you recover. If the illness occurs during the last week of your tablets, miss out the seven pill-free days and start a new pack of tablets straightaway. This means you may not have a period until the end of the two packets.
Please note: co-cyprindiol taken as a contraceptive will not protect you from sexually transmitted infections or HIV infection. If you are concerned about either of these, please ask your pharmacist or doctor for advice on safe sex.
There is a slightly increased risk of a clot in a blood vessel (thromboembolism) with hormonal contraceptives like co-cyprindiol, particularly during the first year of use. Travelling that involves long periods of sitting still (for example, flying for more than three hours) can add to the risk of a blood clot. It's always a good idea to exercise your feet and ankles regularly while travelling, and you may wish to consider wearing flight socks during long flights.
Taking hormonal contraception can increase the risk of some types of cancer. Research suggests a small increased risk of breast and cervical cancer in women taking co-cyprindiol. Your doctor will be able to discuss the risks of this with you.
Treatment with hormones can affect your mood and may impact on your mental health. Speak to your doctor if you are worried about any mood changes after starting treatment with co-cyprindiol.
Before having any kind of surgery, you must tell your doctor or surgeon that you are taking these tablets. This is because your doctor may decide that you need to stop the treatment for a period of time to reduce your risk of unwanted blood clots.
It is likely to take at least 3-4 months for your skin condition to clear up. Your doctor will regularly review your progress during this time. If you still need contraception once the course of treatment with co-cyprindiol has stopped, an alternative contraceptive pill will be prescribed for you.
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Can co-cyprindiol cause problems?
Zurück zum InhaltAlong with their useful effects, most medicines can cause unwanted side-effects although not everyone experiences them. The table below contains some of the common ones associated with co-cyprindiol. You will find a full list in the manufacturer's information leaflet supplied with the tablets. The unwanted effects often improve as your body adjusts to the new medicine, but speak with your doctor or pharmacist if any of the following continue or become troublesome.
Common co-cyprindiol side-effects (these affect fewer than 1 in 10 women) | Was kann ich tun, wenn ich das erlebe? |
Übelkeit, Bauchschmerzen (abdominale Schmerzen) | Eat simple meals - avoid rich and spicy food (see also the information above on bouts of sickness) |
Kopfschmerzen | Ask your pharmacist to recommend a suitable painkiller. If the headache continues or is sudden and severe, contact your doctor for advice |
Breast tenderness, increased weight, mood changes | Wenn es problematisch ist, sprechen Sie mit Ihrem Arzt |
Wichtig: co-cyprindiol can have some serious side-effects, but these are very uncommon. If you experience any of the following symptoms, stop taking the tablets and contact your doctor for advice straightaway:
Any sudden or severe chest pain.
Any sudden breathlessness or if you cough up any blood.
Any swelling or pain in a leg.
Severe stomach pain.
An unusually painful or severe headache, or any loss of your sight or hearing, or any difficulty swallowing.
A bad fainting attack, a fit, or any numbness on one side of your body,
Any yellowing of your skin or of the whites of your eyes (jaundice).
Wenn Sie andere Symptome bemerken, die Ihrer Meinung nach auf die Tabletten zurückzuführen sein könnten, sprechen Sie bitte mit Ihrem Arzt oder Apotheker für weitere Ratschläge.
How to store co-cyprindiol
Zurück zum InhaltBewahren Sie alle Medikamente außerhalb der Reichweite und Sicht von Kindern auf.
An einem kühlen, trockenen Ort aufbewahren, fern von direkter Hitze und Licht.
Wichtige Informationen über alle Medikamente
Zurück zum InhaltWichtige Informationen über alle Medikamente
Never take more than the prescribed dose. If you suspect that you or someone else might have an overdose of this medicine, go to the accident and emergency department of your local hospital. Take the container with you, even if it is empty.
Dieses Medikament ist für Sie. Geben Sie es niemals an andere Personen weiter, auch wenn deren Zustand ähnlich erscheint wie Ihrer.
Wenn Sie Medikamente kaufen, fragen Sie immer einen Apotheker, ob sie mit Ihren anderen Medikamenten verträglich sind.
Bewahren Sie keine abgelaufenen oder unerwünschten Medikamente auf. Bringen Sie sie zu Ihrer örtlichen Apotheke, die sie für Sie entsorgt.
If you have any questions about this medicine, please ask your pharmacist for advice.
Berichten Sie Nebenwirkungen eines Medikaments oder Impfstoffs
Wenn Sie Nebenwirkungen bemerken, können Sie diese online über die Yellow Card Webseite.

Unsicher beim Mischen von Medikamenten?
Überprüfen Sie mögliche Wechselwirkungen zwischen Medikamenten, Nahrungsergänzungsmitteln und Lebensmitteln, bevor Sie sie zusammen einnehmen.
Häufig gestellte Fragen
How long will it take for co-cyprindiol to improve my skin condition?
It usually takes at least 3-4 months for your skin condition to clear up. Your doctor will monitor your progress regularly during this time.
What should I do if I become pregnant while taking co-cyprindiol?
If you suspect you might be pregnant, stop taking co-cyprindiol immediately and contact your doctor or pharmacist for a pregnancy test.
Does co-cyprindiol protect against sexually transmitted infections?
No, co-cyprindiol, when taken as a contraceptive, does not protect you from sexually transmitted infections or HIV infection. If you have concerns about these, you should ask your pharmacist or doctor for advice on safe sex.
Can I take co-cyprindiol if I am going to have surgery?
You must inform your doctor or surgeon that you are taking co-cyprindiol before any kind of surgery. Your doctor may decide you need to stop the treatment temporarily to lower your risk of unwanted blood clots.
What should I do if I have a severe headache, or a headache that doesn't go away?
If you experience a sudden and severe headache, or if a headache continues and is troublesome, you should contact your doctor for advice. Your pharmacist can also recommend a suitable painkiller for common headaches.
What happens if I forget to take a co-cyprindiol tablet, especially if I'm also using it for contraception?
If you forget to take a tablet, take it as soon as you remember, then take the next dose at your usual time (even if it means taking two tablets on the same day). If you are more than 12 hours late, your protection against pregnancy could be reduced. In this case, use a barrier method like a condom for the next seven days, or avoid sex. If these seven days extend beyond the end of your current pack, start a new pack straight away without a tablet-free period.
Can traveling increase my risk of blood clots while on co-cyprindiol?
Yes, traveling that involves long periods of sitting still, such as flying for more than three hours, can increase the risk of a blood clot. It's advisable to regularly exercise your feet and ankles during travel, and you might consider wearing flight socks on long flights.
Weiterführende Literatur und Referenzen
- Manufacturer's PIL, Dianette®; Bayer plc, The electronic Medicines Compendium. Dated February 2023.
- Medikamente Komplett BNF 89. Ausgabe; Britische Ärztevereinigung und Königliche Pharmazeutische Gesellschaft von Großbritannien, London.
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Über den AutorVollständige Biografie anzeigen

Michael Stewart, MRPharmS
Manager für die Überprüfung von Beipackzetteln – Auftragnehmer, Apotheker
BPharm (Hons), MRPharmS
Michael ist ein Gemeindapotheker, der in den Midlands und South Yorkshire praktiziert und über mehr als 20 Jahre Erfahrung in der Beratung zu Medikamenten und medizinischen Bedingungen verfügt. Er hat einen starken Hintergrund in der Gesundheitsausbildung, da er Schulungskurse für Apothekenteams und Mitarbeiter von Pflegeeinrichtungen, einschließlich Krankenschwestern, erstellt und durchgeführt hat. Er hat auch zu Apothekenbeiräten für das Management von geringfügigen Erkrankungen in der Gemeinschaft beigetragen.
Über den Rezensenten

Sid Dajani
Sultan Dajani qualifizierte sich 1994 an der London School of Pharmacy und wurde das jüngste gewählte Mitglied des Rates der Royal Pharmaceutical Society seit ihrer Gründung im Jahr 1842.
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Nächste Überprüfung fällig: 4. Dez. 2027
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