Etonogestrel-Verhütungsimplantat
Nexplanon
Begutachtet von Sid DajaniZuletzt aktualisiert von Michael Stewart, MRPharmSLast updated 9. Mai 2023
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The etonogestrel implant is used to prevent pregnancy.
Read the manufacturer's information leaflet from inside the pack before having the implant.
As with most hormonal contraceptives, side-effects include breast discomfort, fluid retention and an increase in acne.
At a glance
Etonogestrel is a long-acting contraceptive implant inserted under the skin of your upper arm.
It slowly releases a hormone to prevent pregnancy for up to three years.
The implant works by stopping egg release, changing the womb lining and thickening cervical mucus.
Irregular bleeding is a common side-effect, and periods may become infrequent or stop.
Inform your doctor about your implant if prescribed other medicines, as some can reduce its effectiveness.
Contact your doctor if you suspect pregnancy or notice changes to the implant or surrounding skin.
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About etonogestrel contraceptive implants
Art des Medikaments | Progestogen |
Verwendet für | Verhütung |
Auch genannt | Nexplanon® |
Verfügbar als | Implant |
Etonogestrel is a progestogen, which is a female sex hormone similar to the progesterone hormone made naturally by your ovaries. An implant containing etonogestrel is a long-acting, effective and convenient form of Verhütung. The implant is a small flexible tube which is put under the surface of your skin on your upper arm. It releases etonogestrel slowly into your bloodstream. Each implant will provide contraception for up to three years. Nexplanon® is the brand name of the etonogestrel implant prescribed in the UK at present.
Etonogestrel works mainly by stopping ovulation (the release of an egg from the ovary). It also changes the lining of your womb (uterus) to make it less likely that an egg would attach to it, even if an egg were to fertilise. In addition, the mucus which forms a plug in your cervix becomes thicker. This stops sperm getting through to the uterus to fertilise an egg.
Before you have an etonogestrel implant
Zurück zum InhaltSome medicines are not suitable for people with certain conditions, and sometimes a medicine may only be used if extra care is taken. For these reasons, before having Nexplanon® it is important that your doctor knows:
Wenn Sie denken, dass Sie bereits schwanger sein könnten.
Wenn Sie Probleme mit der Funktionsweise Ihrer Leber haben.
Wenn Sie ein Problem mit Ihren Arterien haben, das als Arterienerkrankung bezeichnet wird.
Wenn Sie eine Eierstockzyste haben oder vaginalen Blutungen, die nicht Ihre normale Monatsblutung sind.
If you have systemic lupus erythematosus, an inflammatory condition often called SLE.
If you have ever had an ectopic pregnancy or if you have developed severe itching or yellowing of your skin or the whites of your eyes (jaundice) during a pregnancy.
Wenn Sie Brustkrebs hatten oder einen Krebs, von dem Ihnen gesagt wurde, dass er von einem Sexualhormon abhängig ist.
Wenn Sie eine seltene erbliche Bluterkrankung namens Porphyrie haben.
Wenn Sie jemals an einer depressiven Erkrankung gelitten haben.
Wenn Sie jemals eine allergische Reaktion auf ein Medikament hatten.
If you are taking any other medicines, including those available to buy without a prescription, as well as herbal and complementary medicines. This is because some medicines interfere with the way progestogen contraceptives work.
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How an etonogestrel implant is inserted
Zurück zum InhaltBefore you are given the implant you will be asked to read the printed information leaflet from the implant package. The manufacturer's leaflet will give you important information about the implant and will provide a full list of the side-effects which you may experience from it. If, as a result of reading the leaflet, you have any questions, please discuss them with your doctor/nurse before you have the implant.
The implant will be inserted for you by a person who has been specially trained. A check will be made to ensure it is inserted correctly. Once this is confirmed, it is effective straightaway.
The implant is usually first inserted within five days of a period starting, to ensure that you are not pregnant. It will be put in the inner side of your upper arm. You will be given an injection of local anaesthetic to numb your skin, and a special needle will be used to put the implant in place. The area around the implant may be bruised and sore for a few days, but the wound will soon heal just like any other small cut.
You will be given a User Card which contains some details for you to keep. This will note the date the implant was inserted and will give a suggested date for it to be removed/replaced.
Das Beste aus Ihrer Behandlung herausholen
Zurück zum InhaltThe release of progestogen from the implant will usually cause changes to the pattern of your periods. During the first few months, it is common to have irregular bleeding. This usually settles after the first year, but it may remain. Sometimes periods are heavier and longer than before, and sometimes periods become infrequent and light, or even stop altogether. One in five women with the implant have no bleeding.
If you do develop irregular bleeding, mention it to your doctor. Irregular bleeding can occasionally be due to another reason - for example, an infection, which may need to be treated.
You may gain a little weight. Eating a well-balanced diet and taking regular exercise can help minimise this, but if it is a concern to you, discuss it with your doctor.
It is important to check your breasts regularly for any lumps or bumps. Speak with your doctor if you notice any changes.
If at any time you suspect that you may be pregnant, make an appointment to see your doctor as soon as possible. You should also make an appointment to see your doctor if you notice any changes to the feel of the implant, or to the look of the skin around where the implant was inserted.
Some medicines can reduce the effectiveness of this contraceptive. These include medicines for epilepsy, medicines to treat fungal infections, the herbal preparation St John's wort, and medicines used to treat tuberculosis (TB). Tell the doctor that you have a progestogen implant if you are prescribed any other medicines. If you buy any medicines 'over the counter', ask the pharmacist for advice.
Please note: the implant will not protect you against HIV (AIDS) or any other sexually transmitted infections.
The implant can be taken out at any time if you request removal. It loses its effect immediately after being removed. If you do not want to become pregnant, you must use another form of contraception straightaway afterwards.
A replacement implant is needed every three years if you wish to continue with this form of contraception. It requires a small procedure under local anaesthetic to remove the old implant and put in a new one.
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Can an etonogestrel implant cause problems?
Zurück zum InhaltAlong with their useful effects, most medicines can cause unwanted side-effects although not everyone experiences them. The table below contains some of the most common ones associated with etonogestrel implants. You will find a full list in the manufacturer's information leaflet that has been given to you. The unwanted effects often improve as your body adjusts to the new medicine, but speak with your doctor or pharmacist if any of the following continue or become troublesome.
Very common Nexplanon® side-effects (these affect more than 1 in 10 women) | Was kann ich tun, wenn ich das erlebe? |
Kopfschmerzen | Trinken Sie viel Wasser und bitten Sie einen Apotheker, ein geeignetes Schmerzmittel zu empfehlen. Wenn die Kopfschmerzen anhalten, informieren Sie Ihren Arzt |
Vaginal infections, acne, increased weight, breast tenderness, irregular periods | If you are concerned about any of these, speak with your doctor |
Common Nexplanon® side-effects (these affect fewer than 1 in 10 women) | Was kann ich tun, wenn ich das erlebe? |
Feeling sick (nausea), wind (flatulence), tummy (abdominal) pain | This does not usually last for long, but in the meantime, stick to simple meals |
Pain near the implant | This should pass as the wound heals |
Change in appetite, lack of interest in sex, mood changes, hot flushes, feeling dizzy or tired, hair thinning, painful periods, flu-like symptoms | Wenn es problematisch ist, sprechen Sie mit Ihrem Arzt |
If you experience any other symptoms which you think may be due to the implant, speak with your doctor or pharmacist for advice.
Wichtige Informationen über alle Medikamente
Zurück zum InhaltWichtige Informationen über alle Medikamente
If you are having an operation or any dental treatment, tell the person carrying out the treatment about all the medicines you are using.
If you have any questions about your medicines, ask your pharmacist.
Berichten Sie Nebenwirkungen eines Medikaments oder Impfstoffs
Wenn Sie Nebenwirkungen bemerken, können Sie diese online über die Yellow Card website.

Unsicher beim Mischen von Medikamenten?
Überprüfen Sie mögliche Wechselwirkungen zwischen Medikamenten, Nahrungsergänzungsmitteln und Lebensmitteln, bevor Sie sie zusammen einnehmen.
Häufig gestellte Fragen
How soon after insertion is the etonogestrel implant an effective contraceptive?
The implant starts working immediately after it has been correctly inserted. This is typically done within five days of your period starting to ensure you are not pregnant at the time of insertion.
I'm concerned about irregular bleeding; should I always contact my doctor?
Yes, it is important to mention any irregular bleeding to your doctor. While changes to your period pattern are common with the implant, irregular bleeding can sometimes indicate another issue, such as an infection, which might require treatment.
Can the etonogestrel implant protect me from sexually transmitted infections (STIs)?
No, the etonogestrel implant is a contraceptive and will not protect you against HIV (AIDS) or any other sexually transmitted infections.
What happens if I decide I want to stop using the implant before the three years are up?
The implant can be removed at any time if you request it. Once removed, its contraceptive effect stops immediately. If you wish to avoid pregnancy, you must start using another form of contraception straight away after removal.
Will I need another procedure once my three years with the implant are finished?
Yes, if you wish to continue using this method of contraception, a replacement implant is required every three years. This involves a small procedure under local anaesthetic to remove the old implant and insert a new one.
What should I do if I notice any changes to the implant site on my arm?
You should make an appointment to see your doctor as soon as possible if you notice any changes to the feel of the implant, or to the appearance of the skin around where the implant was inserted.
Weiterführende Literatur und Referenzen
- Manufacturer's PIL, Nexplanon® 68 mg implant for subdermal use; Organon Pharma (UK) Ltd, The electronic Medicines Compendium. Dated April 2022.
- Medikamente Komplett BNF 89. Ausgabe; Britische Ärztevereinigung und Königliche Pharmazeutische Gesellschaft von Großbritannien, London.
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About the authorView full bio

Michael Stewart, MRPharmS
Manager für die Überprüfung von Beipackzetteln – Auftragnehmer, Apotheker
BPharm (Hons), MRPharmS
Michael ist ein Gemeindapotheker, der in den Midlands und South Yorkshire praktiziert und über mehr als 20 Jahre Erfahrung in der Beratung zu Medikamenten und medizinischen Bedingungen verfügt. Er hat einen starken Hintergrund in der Gesundheitsausbildung, da er Schulungskurse für Apothekenteams und Mitarbeiter von Pflegeeinrichtungen, einschließlich Krankenschwestern, erstellt und durchgeführt hat. Er hat auch zu Apothekenbeiräten für das Management von geringfügigen Erkrankungen in der Gemeinschaft beigetragen.
About the reviewer

Sid Dajani
Sultan Dajani qualified at the London School of Pharmacy in 1994 and became the youngest elected member of the Royal Pharmaceutical Society council since its founding in 1842.
Artikelverlauf
Die Informationen auf dieser Seite wurden von qualifizierten Klinikern verfasst und begutachtet.
Nächste Überprüfung fällig: 4. Nov 2027
9. Mai 2023 | Neueste Version

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