Norethindron bei schmerzhaften oder starken Regelblutungen

What is norethindrone?

Norethindrone (also known as norethisterone) is a man-made form of progesterone, a naturally occurring female sex hormone. It is referred to as a progestin and it has a number of uses. Low doses are used to prevent pregnancy, or as hormone replacement therapy (HRT). Medium-strength tablets (5 mg) such as Aygestin® are used to treat heavy and painful menstrual periods particularly if they are associated with a condition called endometriosis. Aygestin® tablets are also used to treat endometriosis itself. Higher doses are used in the treatment of some female cancers, such as breast cancer.

Endometriosis is a condition where tissue which is normally only found inside the womb (uterus), becomes 'trapped' in other parts of the body, often in the pelvic area or lower abdomen. This causes symptoms such as painful and heavy periods. Treatment aims to reduce the pain and amount of blood loss. Norethindrone can also be considered for heavy periods not associated with endometriosis.

This leaflet discusses norethindrone when it is used to treat endometriosis or painful or heavy periods. There are a number of other medicine leaflets which will give you more information about norethindrone if you are taking it for birth control or as HRT. These are: Progestin-only contraceptive tablets, Combination oral contraceptives and Estrogen and progestin for HRT.

What to know before taking norethindrone

Some medicines are not suitable for people with certain conditions, and sometimes a medicine may only be used if extra care is taken. For these reasons, before you start taking norethindrone it is important that your physician knows:

• Wenn Sie schwanger sind oder stillen.

• Wenn Sie Probleme mit der Funktionsweise Ihrer Leber oder Nierenprobleme haben.

• Wenn Sie Probleme mit dem Herzen oder den Blutgefäßen haben, oder wenn Sie jemals ein Blutgerinnsel in einer Arterie oder Vene hatten.

• If you have any of the following: diabetes, epilepsy, migraine, high blood pressure (hypertension), or asthma.

• Wenn Sie rauchen, übergewichtig sind oder einen hohen Cholesterinspiegel haben.

• Wenn Sie jemals an Krebs erkrankt waren.

• Wenn Sie jemals an einer depressiven Erkrankung gelitten haben.

• Wenn Sie schon einmal eine Gelbfärbung der Haut oder des Weißen Ihrer Augen (Gelbsucht), starken Juckreiz oder eine Hauterkrankung namens Pemphigoid gestationis während einer Schwangerschaft hatten.

• Wenn Sie eine seltene vererbte Blutkrankheit namens Porphyrie haben.

• Wenn Sie andere Arzneimittel einnehmen. Dazu gehören alle Arzneimittel, die Sie einnehmen und die rezeptfrei erhältlich sind, sowie pflanzliche und ergänzende Arzneimittel.

• Wenn Sie schon einmal eine allergische Reaktion auf ein Arzneimittel hatten.
  

How to take norethindrone tablets

• Before you start this treatment, read the manufacturer's printed information leaflet from inside your pack. The manufacturer's leaflet will give you more information about norethindrone and a full list of side-effects which you may experience from taking it.

• Take norethindrone exactly as your physician tells you to. You may be asked to take the tablets regularly each day, or to take them just on certain days of your monthly cycle. This information will be printed on the label of your pack of tablets to remind you, but if you are still unsure ask your pharmacist for further advice.

• For treatment of endometriosis it is usual to start with a low dose of half to one tablet (2.5 mg-5 mg) each day. Your physician will ask you to increase your dose slightly every two weeks until you are taking three tablets (15 mg) each day.

• If you are taking norethindrone for painful or heavy menstrual periods, the usual dose is between half and two tablets each day (2.5 mg-10 mg) for five to ten days in each menstrual cycle.

• Swallow the tablets with a drink of water. You can take norethindrone tablets either before or after meals.

• Try to take your doses at the same times of day, as this will help you to remember to take them.

• Wenn Sie vergessen haben, eine Dosis zur gewohnten Zeit einzunehmen, nehmen Sie sie ein, sobald Sie sich daran erinnern, es sei denn, es ist fast Zeit für die nächste Dosis; in diesem Fall lassen Sie die vergessene Dosis aus. In diesem Fall lassen Sie die vergessene Dosis aus. Denken Sie daran, Ihre nächste Dosis zum richtigen Zeitpunkt einzunehmen, aber nehmen Sie nicht zwei Dosen zusammen ein, um eine vergessene Dosis nachzuholen.

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• Try to keep all your regular appointments with your physician. This is so your physician can check on your progress.

• You should avoid getting pregnant as norethindrone can affect a developing baby. Use barrier methods of birth control (such as a condom) if you have sex whilst taking norethindrone. If you need further birth control (contraception) advice, speak with your physician.

• If you have diabetes you may need to check your blood sugar (glucose) more frequently, as norethindrone can affect the levels of sugar in your blood. Your physician will be able to advise you about this.

• If you are due to have surgery or any medical treatment, tell the person carrying out the treatment that you are taking norethindrone.

Norethindrone side effects and problems

Along with their useful effects, most medicines can cause unwanted side-effects although not everyone experiences them. The table below contains some of the most common ones associated with norethindrone. You will find a full list in the manufacturer's information leaflet supplied with your medicine. The unwanted effects often improve as your body adjusts to the new medicine, but speak with your physician or pharmacist if any of the following continue or become troublesome.

Important: norethindrone can also have some serious side-effects, although these occur only rarely. If you experience any of the following symptoms, stop taking the tablets and contact your physician for advice straightaway:

• Ein Schmerz- oder Engegefühl in der Brust.

• Störungen des Seh- und Hörvermögens.

• Ungewöhnlich starke Kopfschmerzen.

• Gelbfärbung der Haut oder des Weißen in den Augen (Gelbsucht).

Wenn Sie andere Symptome haben, von denen Sie glauben, dass sie auf dieses Arzneimittel zurückzuführen sind, sprechen Sie mit Ihrem Arzt oder Apotheker.

How to store norethindrone tablets

• Bewahren Sie alle Arzneimittel außerhalb der Reichweite und Sichtweite von Kindern auf.

• An einem kühlen, trockenen Ort aufbewahren, vor direkter Hitze und Licht schützen.

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