Can I take Am and Sertraline together?

Why this happens

Both sertraline and St John's Wort increase the levels of serotonin in the brain. When used together, they can raise these levels to a point that becomes toxic to the body. Additionally, St John's Wort can change how your liver processes sertraline, making the levels of the medicine in your blood unpredictable.

Do not take St John's Wort if you are already taking sertraline. If you are currently taking both, do not stop suddenly, but contact your GP or pharmacist immediately for advice on how to stop safely. If you experience severe shivering, fever, or confusion, seek urgent medical help.

Taking multiple medicines? Our Medicines Interaction Checker helps you check whether your prescriptions, over-the-counter medicines, and supplements are safe to take together. Simply search for your medicines to see potential interactions and what to do about them.

Disclaimer

This information is for general educational purposes only and should not be relied upon as a substitute for professional medical advice. Always consult your GP, pharmacist, or another qualified healthcare professional before making decisions about your medications. Individual circumstances may vary, and only a healthcare professional who knows your medical history can provide personalised guidance.