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Co-phenotrope tablets for diarrhoea

The usual dose for acute diarrhoea in an adult is four tablets to start with, followed by two tablets every six hours until the diarrhoea is controlled. Do not take more than 10 tablets in 24 hours.

When you have diarrhoea it is important that you have lots of water to drink to prevent you from becoming lacking in fluid in the body (dehydrated). Eat as normally as possible, as soon as you feel able.

If your symptoms continue for more than 48 hours, speak with a doctor for advice if you have not already done so.

Co-phenotrope must not be taken by children under 16 years of age unless prescribed by a doctor.

At a glance

  • Co-phenotrope is a medicine used to treat sudden-onset diarrhoea.

  • It works by slowing down your bowel activity so contents pass through more slowly.

  • For adults, the usual starting dose is four tablets, then two tablets every six hours.

  • Do not take more than 10 tablets in 24 hours.

  • Drink plenty of fluids to prevent dehydration while taking this medicine.

  • Speak to a doctor if your symptoms worsen or do not improve within 48 hours.

  • Common side effects include feeling tired, dizzy, or having a headache.

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About co-phenotrope

Art des Medikaments

An antimotility medicine

Verwendet für

Durchfall

Auch genannt

Diphenoxylate hydrochloride with atropine sulfate

Verfügbar als

Tabletten

Co-phenotrope is used in acute diarrhoea (this is diarrhoea which starts suddenly and lasts less than two weeks). It contains two ingredients: diphenoxylate hydrochloride and atropine sulfate. It is the diphenoxylate hydrochloride which is the main ingredient.

The most common cause of acute diarrhoea is infection. Other causes include drinking lots of beer, as a side-effect from other medicines, and anxiety. In most cases the diarrhoea settles within a few days, although it may take longer in some people. The main treatment is to have lots to drink to prevent lack of fluid in the body (dehydration). Antidiarrhoeal medicines like co-phenotrope may not be necessary; however, if you wish to reduce the number of trips that you need to make to the toilet, it can be useful. Most people only need to take it for a few days.

Diphenoxylate works by slowing down the activity of your bowel. This reduces the speed at which the contents pass through, and so food remains in your intestines for longer. This allows more water to be absorbed back into your body and results in firmer stools that are passed less often.

Because co-phenotrope regulates the passage of food through the digestive system, the tablets are also prescribed to help people regulate their bowel activity following surgery on the intestines.

Some medicines are not suitable for people with certain conditions, and sometimes a medicine may only be used if extra care is taken. For these reasons, before you start taking co-phenotrope it is important that your doctor or pharmacist knows:

  • Wenn Sie schwanger sind oder stillen.

  • Wenn Sie Probleme mit der Funktionsweise Ihrer Leber oder Ihrer Nieren haben.

  • Wenn Sie Atemprobleme haben, wie Asthma oder chronisch obstruktive Lungenerkrankung (COPD).

  • Wenn Sie Prostataprobleme oder Schwierigkeiten beim Wasserlassen haben.

  • Wenn Ihnen gesagt wurde, dass Sie niedrigen Blutdruck haben.

  • Wenn Sie Probleme mit Ihrer Schilddrüse oder Ihren Nebennieren haben.

  • Wenn Sie Epilepsie haben.

  • If you have a problem in your bile duct.

  • If you have a bowel obstruction or an inflammatory bowel problem.

  • Wenn Sie an einer Erkrankung leiden, die Muskelschwäche verursacht, genannt Myasthenia gravis.

  • If you have ever had a drug addiction.

  • Wenn Sie jemals eine allergische Reaktion auf ein Medikament hatten.

  • Wenn Sie andere Medikamente einnehmen. Dazu gehören alle Medikamente, die Sie einnehmen und die ohne Rezept erhältlich sind, sowie pflanzliche und ergänzende Medikamente.

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  • Before you start this treatment, read the manufacturer's printed information leaflet from inside your pack. The manufacturer's leaflet will give you more information about the tablets and a full list of the side-effects which you may experience from taking them.

  • Start by taking four tablets, and then take a further two tablets every six hours until the diarrhoea is controlled. Do not take more than 10 tablets in 24 hours.

  • Co-phenotrope should not be taken by a child under 16 years of age unless it is on the advice of a doctor. If your child has been prescribed co-phenotrope, check the label carefully to make sure you know what dose to give, as the dose will depend upon your child's age.

  • If you forget to take a dose, do not worry, just take a dose after the next time you pass some diarrhoea. Do not take two doses together to make up for a missed dose.

  • It is important that you have lots to drink to prevent you from becoming lacking in fluid in the body (dehydrated). Drinking plain water is ideal, but juice and/or soup are also suitable. Try to avoid drinks that contain a lot of sugar, such as cola or pop, as they can sometimes make diarrhoea worse.

  • Oral rehydration salts can be taken to help prevent dehydration and replace lost salts. These are especially recommended for children and for people who are frail or who have underlying health problems. You can buy these from a pharmacy.

  • Eat small, light meals as soon as you are able. Plain foods such as wholemeal bread and rice are good foods to try eating first.

  • If your symptoms continue for more than 48 hours, speak with a doctor or pharmacist for advice if you have not already done so.

  • If your symptoms get worse, or if you develop a high temperature, or if you pass blood in the diarrhoea, you should ask your doctor or pharmacist for advice as soon as possible.

  • If you buy any medicines check with a pharmacist that they are suitable to take with co-phenotrope. This is because the risk of side-effects can be increased when co-phenotrope tablets are taken with some other medicines.

  • Do not take more than the prescribed dose. If you suspect that someone has taken an overdose of this medicine, or that a child has taken it by accident, go to the accident and emergency department of your local hospital straightaway. Take the container with you, even if it is empty.

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Along with their useful effects, most medicines can cause unwanted side-effects although not everyone experiences them. The table below contains some of the most common ones associated with co-phenotrope. You will find a full list in the manufacturer's information leaflet supplied with your medicine. The unwanted effects often improve as your body adjusts to the new medicine, but speak with your doctor or pharmacist if any of the following continue or become troublesome.

Co-phenotrope side-effects

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Fühlen Sie sich müde, schläfrig oder schwindelig

Wenn dies passiert, fahren Sie nicht und benutzen Sie keine Werkzeuge oder Maschinen, bis Sie sich besser fühlen

Kopfschmerzen

Trinken Sie viel Wasser und bitten Sie Ihren Apotheker, ein geeignetes Schmerzmittel zu empfehlen. Wenn die Kopfschmerzen anhalten, informieren Sie Ihren Arzt

Tummy (abdominal) discomfort, feeling sick (nausea)

Try taking the tablets after eating some food if you are not already doing so

Verstopfung

Stop taking co-phenotrope

Feeling confused or restless, mood changes, high temperature (fever), dry mouth, difficulty passing urine, feeling flushed

These should soon pass. If any become troublesome, stop taking co-phenotrope

Wenn Sie andere Symptome bemerken, die Ihrer Meinung nach auf das Medikament zurückzuführen sein könnten, sprechen Sie mit Ihrem Arzt oder Apotheker.

  • Bewahren Sie alle Medikamente außerhalb der Reichweite und Sicht von Kindern auf.

  • An einem kühlen, trockenen Ort aufbewahren, fern von direkter Hitze und Licht.

Wichtige Informationen über alle Medikamente

Wenn Sie sich einer Operation oder Zahnbehandlung unterziehen, informieren Sie die Person, die die Behandlung durchführt, welche Medikamente Sie einnehmen.

Dieses Medikament ist für Sie. Geben Sie es niemals an andere Personen weiter, auch wenn deren Zustand ähnlich erscheint wie Ihrer.

Bewahren Sie keine abgelaufenen oder unerwünschten Medikamente auf. Bringen Sie sie zu Ihrer örtlichen Apotheke, die sie für Sie entsorgt.

Wenn Sie Fragen zu diesem Medikament haben, fragen Sie Ihren Apotheker.

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Häufig gestellte Fragen

Can co-phenotrope be used for chronic or long-term diarrhoea?

No, co-phenotrope is specifically used for acute diarrhoea, which starts suddenly and lasts less than two weeks. The article does not mention its use for chronic conditions.

What if I experience constipation while taking co-phenotrope?

If you experience constipation, you should stop taking co-phenotrope. This is listed as one of the side-effects of the medicine.

Are there any specific foods or drinks I should avoid while taking co-phenotrope for diarrhoea?

Yes, you should try to avoid drinks that contain a lot of sugar, such as cola or pop, as they can sometimes make diarrhoea worse. The article suggests plain water, juice, and/or soup for hydration.

How soon can I expect co-phenotrope to work in controlling my diarrhoea?

The article states that you should take two additional tablets every six hours until the diarrhoea is controlled. It implies that the medication should work within a short period to reduce the number of trips to the toilet.

My diarrhoea seems to be getting worse, or I have new symptoms like a high temperature or blood. What should I do?

If your symptoms get worse, or if you develop a high temperature, or if you pass blood in the diarrhoea, you should ask your doctor or pharmacist for advice as soon as possible.

Since co-phenotrope works by slowing bowel activity, can it be helpful for other digestive issues besides diarrhoea?

Yes, because co-phenotrope regulates the passage of food through the digestive system, it is also prescribed to help people regulate their bowel activity following surgery on the intestines.

Can I take other over-the-counter medicines while I'm using co-phenotrope?

If you buy any medicines, you should check with a pharmacist that they are suitable to take with co-phenotrope. This is important because the risk of side-effects can be increased when co-phenotrope tablets are taken with some other medicines.

Weiterführende Literatur und Referenzen

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About the authorView full bio

Author image

Michael Stewart, MRPharmS

Manager für die Überprüfung von Beipackzetteln – Auftragnehmer, Apotheker

BPharm (Hons), MRPharmS

Michael ist ein Gemeindapotheker, der in den Midlands und South Yorkshire praktiziert und über mehr als 20 Jahre Erfahrung in der Beratung zu Medikamenten und medizinischen Bedingungen verfügt. Er hat einen starken Hintergrund in der Gesundheitsausbildung, da er Schulungskurse für Apothekenteams und Mitarbeiter von Pflegeeinrichtungen, einschließlich Krankenschwestern, erstellt und durchgeführt hat. Er hat auch zu Apothekenbeiräten für das Management von geringfügigen Erkrankungen in der Gemeinschaft beigetragen.

About the reviewer

Author image

Sid Dajani

Sultan Dajani qualified at the London School of Pharmacy in 1994 and became the youngest elected member of the Royal Pharmaceutical Society council since its founding in 1842.

Artikelverlauf

Die Informationen auf dieser Seite wurden von qualifizierten Klinikern verfasst und begutachtet.

  • Next review due: 26 Oct 2027
  • 27. Apr 2023 | Neueste Version

    Zuletzt aktualisiert von

    Michael Stewart, MRPharmS

    Begutachtet von

    Sid Dajani
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