Dapson-Tabletten

About dapsone

Dapsone is an antibacterial medicine. It is prescribed for the treatment of two completely different conditions - a disease called leprosy, and a skin condition called dermatitis herpetiformis. It is also prescribed for people with a weakened immune system to protect them from pneumonia caused by an infection with germs (bacteria) called Pneumocystis jirovecii.

Leprosy is an infectious disease which is rare in the UK. Dapsone works by stopping the growth of the bacteria that are causing the infection. It is prescribed alongside one or more other medicines, as part of multidrug therapy (MDT).

Dermatitis herpetiformis is a skin condition, the main symptom of which is a very itchy rash. It is caused by intolerance to a food ingredient called gluten, which is a natural substance found in foods such as wheat, rye and barley. It is often linked to a condition called coeliac disease, which is also caused by gluten intolerance. Dermatitis herpetiformis can be effectively treated with dapsone and a gluten-free diet.

Dapsone is also prescribed to protect people who have a weakened immune system from pneumonia. Pneumonia, caused by bacteria called Pneumocystis jirovecii, is a serious lung infection which can affect people with a weakened immune system, such as people with AIDS.

Before taking dapsone

Some medicines are not suitable for people with certain conditions, and sometimes a medicine can only be used if extra care is taken. For these reasons, before you start taking dapsone it is important that your doctor knows:

• If you are pregnant, trying for a baby or breastfeeding. This is because you will need to take a supplement of folic acid if you are expecting a baby.

• If you have a heart condition, or any problems with your lungs.

• If you have a lack of iron in your blood (anaemia). This will need treating before you take dapsone.

• If you know you have glucose 6-phosphate dehydrogenase deficiency. This is a genetic disorder where there is a lack of an enzyme often known as G6PD. People with this disorder have problems after eating foods such as fava beans.

• Wenn Sie eine seltene vererbte Blutkrankheit namens Porphyrie haben.

• Wenn Sie andere Arzneimittel einnehmen. Dazu gehören alle Arzneimittel, die Sie einnehmen und die rezeptfrei erhältlich sind, sowie pflanzliche und ergänzende Arzneimittel.

• If you have ever had an allergic reaction to a medicine. It is particularly important that you let your doctor know if you have had an allergic reaction to a sulfonamide medicine used to treat an infection.

How to take dapsone

• Before you start taking the tablets, read the manufacturer's printed information leaflet from inside the pack. It will give you more information about dapsone and will provide you with a full list of the side-effects which you could experience from taking it.

• Your doctor will tell you what dose is right for you - please take dapsone exactly as your doctor tells you to. It is usual to be prescribed one dose to take every day. There are two strengths of tablet - 50 mg and 100 mg. Each time you collect a new supply, check to make sure you get the same strength tablets as before, and ask your pharmacist for advice if you have any questions. The following doses (for adults) are intended as a guide only:

  • For leprosy: 50-100 mg daily.

  • For dermatitis herpetiformis: 25-300 mg daily.

  • For prevention of pneumonia: 100 mg daily.

• You can take dapsone at whatever time of day you find easiest to remember, but try to take your doses at the same time of day each day, as this will help you to remember to take your doses regularly. Swallow the tablet with a drink of water. You can take the tablet either before or after meals.

• Wenn Sie die Einnahme einer Dosis vergessen haben, holen Sie sie nach, sobald Sie sich daran erinnern. Wenn Sie sich erst am nächsten Tag daran erinnern, lassen Sie die vergessene Dosis vom Vortag weg und nehmen Sie die fällige Dosis wie gewohnt ein. Nehmen Sie nicht zwei Dosen zur gleichen Zeit ein, um eine vergessene Dosis nachzuholen.

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• Try to keep your regular appointments with your doctor. This is so your doctor can check on your progress. Your doctor will want you to have some blood tests during this treatment.

• Take the tablets regularly every day - do not stop taking dapsone unless your doctor tells you to do so. Your treatment may last for several months or years.

• If you are taking dapsone for dermatitis herpetiformis, you will also have been given some advice about which foods to avoid as part of a gluten-free diet. It is important that you follow this dietary advice carefully.

• Dapsone tablets can stop the oral typhoid vaccine from working. If you are due to have any vaccinations, please make sure that the person treating you knows that you are taking this medicine.

Can dapsone cause problems?

Along with their useful effects, most medicines can cause unwanted side-effects although not everyone experiences them. The table below contains some of the ones which can occur with dapsone. You will find a full list in the manufacturer's information leaflet supplied with your medicine. Speak with your doctor or pharmacist if any of the following continue or become troublesome.

Wenn Sie andere Symptome haben, von denen Sie glauben, dass sie auf die Tabletten zurückzuführen sind, sprechen Sie bitte mit Ihrem Arzt oder Apotheker, um weiteren Rat einzuholen.

How to store dapsone

• Bewahren Sie alle Arzneimittel außerhalb der Reichweite und Sichtweite von Kindern auf.

• An einem kühlen, trockenen Ort aufbewahren, vor direkter Hitze und Licht schützen.

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