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Decongestants are medicines that are used to help reduce the symptoms of a blocked or stuffy nose. They may be helpful for congestion caused by various conditions. Most commonly, decongestants are used for a cold, sinusitis, hay fever, allergies and rhinitis. These medicines are available as nose drops or nasal sprays and also as tablets, capsules and syrup. Decongestant nose drops or nasal sprays should not be used for more than five days at a time.
These medicines are not suitable for children under 6 years old.
Auf einen Blick
Decongestants are medicines that help ease a blocked or stuffy nose.
They work by reducing swelling in the blood vessels in the nose and sinuses.
They can be sprays, drops, tablets, or syrups, and some are available over the counter.
Nasal decongestant sprays and drops should only be used for 3-5 days.
Decongestants should not be given to children under 6 years old.
Some people with certain health conditions should avoid taking decongestants.
Rare but serious side effects have been linked to pseudoephedrine-containing products.
What are decongestants?
Decongestants are medicines that are used to help ease a blocked or stuffy nose (nasal congestion). Conditions which cause congestion include:
Heuschnupfen or other allergies.
These conditions cause swelling of the tissues and blood vessels that line the nasal passageway and sinuses. This, in turn, causes the nose to become blocked.
A number of decongestants are available in the UK. They include:
Oxymetazoline.
Phenylephrine.
Pseudoephedrine.
Hinweis der Redaktion
Dr. Krishna Vakharia, 21. Februar 2024
A note on pseudoephedrine-containing products.
The Medicines and Healthcare products Regulatory Agency has issued a caution for those using pseudoephedrine-containing products.
There have been rare reports of two conditions associated with pseudoephedrine use - posterior reversible encephalopathy syndrome (PRES) and reversible cerebral vasoconstriction syndrome (RCVS).
Nach einer Überprüfung durch die MHRA wird die Sicherheitsinformation aller pseudoephedrinhaltigen Arzneimittel aktualisiert, um sowohl Patienten als auch Gesundheitsfachkräften klarere Beschreibungen dieser Risiken und potenziellen Risikofaktoren für diese Bedingungen bereitzustellen.
PRES- also known as reversible posterior leukoencephalopathy syndrome (RPLS). This is a rare condition in which parts of the brain are affected by swelling - usually as a result of an underlying cause. Symptoms include headache, changes in vision, and seizures, with some developing other neurological symptoms such as confusion or weakness of one or more limbs. Most patients fully recover.
RCVS - is a neurological disorder. There is a sudden onset of severe headache associated with narrowing of the blood vessels that supply blood to the brain. On brain imaging the narrowing of the blood vessels can look similar to a “string of beads”. Very rarely, RCVS can present as a medical emergency with strokes (ischaemic strokes or bleed), seizure or as brain swelling. Usually, the narrowing resolves by itself within three months, and most patients fully recover.
MHRA is reminding users that:
Pseudoephedrine is for short term use only and should only be used to relieve symptoms of nasal and sinus congestion in colds, flu, and allergies.
No one should take pseudoephedrine if they have high blood pressure (hypertension) or hypertension not controlled by their medicines, or if they have severe acute (sudden onset) or chronic (long-term) kidney disease or kidney failure.
If you experience a severe headache that develops very quickly or you suddenly feel sick or are vomiting, confused or experiencing seizures or changes in vision while taking this medicine, stop taking it immediately and seek urgent medical attention.
A reminder that this is extremely rare - there have only been 4 cases reported by the Gelbe Karte Schema to date- out of 4 million packets sold in 2022.
Some are available as nasal sprays or drops (sometimes referred to as topical decongestants). Some are available to take by mouth as a tablet or syrup. Some are available in both forms.
These medicines come in various brand names. Many are available to buy over the counter from your pharmacy. They may also be available as a combined tablet that contains a decongestant and a painkiller such as paracetamol.
There are a number of other options that are sometimes used to treat nasal congestion. For example, the following may be helpful:
Salt water (saline) nose drops. These are a popular treatment for a stuffy nose in a baby.
Steam inhalations. Steam may help to clear the nasal congestion but only has an effect for a short time. This may be useful before bedtime to help you get off to sleep.
Do decongestants help?
How do decongestants work?
Most decongestants work by reducing the swelling of the blood vessels in your nose, throat and sinuses. As it is this swelling causing the congestion, the medication improves the blocked-up feeling.
Ipratropium nasal spray works slightly differently by drying up the secretions of the nose.
Decongestant nasal sprays tend to have an immediate effect to clear a blocked nose. Oral tablets and capsules may take a little longer to work because they need to be absorbed into the body from the gut.
When are decongestants used or prescribed?
As discussed above, these medicines may be used or prescribed by your doctor to ease nasal congestion for people with the Erkältung, Sinusitis, hay fever, other allergies or rhinitis.
If you have hay fever, they are helpful to use for a few days to clear a blocked nose when you first use a steroid nasal spray. The steroid can then get to the lining of the nose more effectively. If you have acute sinusitis, decongestants can relieve symptoms whilst you are waiting for your immune system to clear the infection. However, they are not thought to shorten the duration of sinusitis.
Decongestant nasal sprays and nose drops should only be used for about 3-5 days at a time. If they are used for longer than this a rebound, more severe congestion of the nose often develops. Oxymetazoline and xylometazoline nasal preparations are thought to be more likely to cause rebound nasal congestion because they are the strongest.
Oral decongestants are not thought to cause this problem when they are stopped. Decongestant sprays and drops are thought to work better than oral tablets or capsules.
Some important considerations
Some important considerations about decongestants relate to:
Children under 6 years old.
Taking other medicines.
Kinder unter 6 Jahren
These medicines should not be used in children under 6 years old. The risk of side-effects is higher than any benefit they may have. Children aged 6 to 12 can use some decongestants following discussion with a pharmacist.
Einnahme anderer Medikamente
It is important to remember that some medicines that treat colds or sinusitis contain other medicines as well. For example, some may contain Paracetamol oder Ibuprofen and some contain alcohol.
This is important if you are already taking paracetamol or ibuprofen to help the symptoms of your infection (for example, a high temperature). You may take too much paracetamol or ibuprofen (overdose) without realising. Taking too much paracetamol can damage your liver.
You should also not use these decongestants while you are taking a certain type of antidepressant called a monoamine-oxidase inhibitor (MAOI) and for two weeks after you stop it. This is because, when taken at the same time as an MAOI antidepressant, decongestants may cause very large increases in blood pressure.
Side-effects of decongestants
Most people are able to take or use decongestant medicine with very few, or no, side-effects. If side-effects do occur, they usually go away after a few days. Some nasal decongestants may produce side-effects such as:
Nasal burning, irritation and dryness.
Übelkeit (Übelkeit).
Oral decongestants may cause side-effects such as:
Unruhe.
Problems with sleeping.
Being aware of a fast or fluttering heartbeat.
See the leaflet that came with your medicines for more detailed information on the side-effects of these medicines.
Can I buy decongestants?
There are a large number of oral and nasal decongestants that you can buy from your local pharmacy or supermarket. They have many different brand names.
Who cannot take decongestants?
Some people should avoid taking decongestants. This includes people who have:
Heart problems, such as coronary artery disease, heart failure or arrhythmias (irregular heart beat).
Kidney problems, such as chronic kidney disease.
Diabetes.
Glaucoma.
An overactive thyroid gland.
Prostate problems, such as difficulty passing urine due to prostate enlargement.
Depression and take an MAOI antidepressant.
Circulation problems, including Raynaud’s phenomenon.
See the leaflet that came with your medicines for more detailed information on who should avoid taking these medicines. If you are unsure whether these medicines are safe for you, always ask your pharmacist or doctor for advice.
Patientenauswahl für Atemwegsmittel

Behandlung und Medikamente
Orale Bronchodilatatoren
Orale Bronchodilatatoren sind Medikamente, die manchmal zur Behandlung von Atemproblemen bei Menschen mit Asthma und anderen lungenbezogenen Problemen wie der chronisch obstruktiven Lungenerkrankung (COPD) eingesetzt werden. Sie werden nicht sehr häufig verwendet, da inhalative Bronchodilatatoren in der Regel besser wirken. In Großbritannien stehen zwei Arten von oralen Bronchodilatatoren zur Verschreibung zur Verfügung. Diese sind Beta2-Agonisten (Salbutamol, Bambuterol und Terbutalin) und Methylxanthine (Theophyllin und Aminophyllin). Orale Bronchodilatatoren helfen, Symptome wie Husten, Keuchen und Atemnot zu lindern, indem sie die Atemwege in den Lungen öffnen, sodass die Luft freier in die Lungen strömen kann.
von Dr. Doug McKechnie, MRCGP

Behandlung und Medikamente
Mukolytika
Schleim (Sputum) wird in den Lungen gebildet. Mukolytika sind Medikamente, die den Schleim weniger dick und klebrig machen und das Abhusten erleichtern. Sie werden normalerweise für Menschen verschrieben, die einen langanhaltenden (chronischen) Husten haben. Sie wirken am besten, wenn sie regelmäßig eingenommen werden.
von Dr. Philippa Vincent, MRCGP
Häufig gestellte Fragen
What is rhinitis?
Rhinitis is a condition that causes inflammation or irritation of the nasal lining, leading to symptoms like a blocked nose. It's one of the conditions for which decongestants might be used to relieve congestion.
Are there any natural remedies for a blocked nose?
Yes, some other options can help with nasal congestion. Salt water (saline) nose drops are a popular treatment, especially for babies. Steam inhalations may also help to clear nasal congestion, though their effect is usually short-lived. They can be useful before bedtime to aid sleep.
Can I use decongestants if I'm taking other cold and flu medicines?
You need to be careful, as some cold or sinusitis medicines already contain other medications like paracetamol or ibuprofen, and some may contain alcohol. If you're also taking paracetamol or ibuprofen separately, you could accidentally take too much, which can be harmful. Always check the ingredients of all medicines you are taking.
Is there a difference in how quickly nasal sprays and oral decongestants work?
Yes, there is. Decongestant nasal sprays typically have an immediate effect in clearing a blocked nose. Oral tablets and capsules, however, may take a little longer to work because they need to be absorbed into your body through your gut before they can take effect.
What is the Yellow Card Scheme and why is it important?
The Yellow Card Scheme is a system where you can report any side-effects you believe you've experienced from medicines or other healthcare products. It's important because it helps pharmacists, doctors, and nurses become aware of new side-effects. By reporting, you contribute to better understanding and safety of medicines. When reporting, you'll need to provide details about the side-effect, the medicine, the person affected, and your contact information.
Weiterführende Literatur und Referenzen
- Husten- und Erkältungsmittel ohne Rezept für Kinder; Arzneimittel- und Gesundheitsprodukte-Bundesbehörde (MHRA), 2014
- Britisches Nationales Arzneimittelverzeichnis (BNF); NICE Evidenzdienste (nur in Großbritannien zugänglich)
- Erkältung; NICE CKS, Februar 2022 (nur für UK-Zugang)
- Sinusitis; NICE CKS, März 2021 (nur UK-Zugang)
- Deckx L, De Sutter AI, Guo L, et al; Nasal decongestants in monotherapy for the common cold. Cochrane Database Syst Rev. 2016 Oct 17;10(10):CD009612. doi: 10.1002/14651858.CD009612.pub2.
- De Sutter AI, Eriksson L, van Driel ML; Oral antihistamine-decongestant-analgesic combinations for the common cold. Cochrane Database Syst Rev. 2022 Jan 21;1(1):CD004976. doi: 10.1002/14651858.CD004976.pub4.
- Watts AM, Cripps AW, West NP, et al; Modulation of Allergic Inflammation in the Nasal Mucosa of Allergic Rhinitis Sufferers With Topical Pharmaceutical Agents. Front Pharmacol. 2019 Mar 29;10:294. doi: 10.3389/fphar.2019.00294. eCollection 2019.
Über den Autor

Jenny Whitehall
BSc (Hons), Diplom in Pharmaziepraxis
Über den RezensentenVollständige Biografie anzeigen

Dr Hayley Willacy, FRCGP
Allgemeinmediziner, Medizinischer Autor
MBChB (1992), DRCOG, DFFP, MRCOG (Part 1) MRCGP (2007), DFSRH (2013), MSc - medical education (2020)
Dr. Hayley Willacy war eine NHS-Hausärztin, die in Nordwestengland arbeitete und 2022 nach 30 Jahren aus der klinischen Praxis ausschied.
Artikelverlauf
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Nächste Überprüfung fällig: 16. Feb 2028
3. Apr 2023 | Neueste Version
2 Oct 2012 | Ursprünglich veröffentlicht
Verfasst von:
Jenny Whitehall

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