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Mitralklappeninsuffizienz

The mitral valve is a heart valve that lies between the left atrium and left ventricle.

Auf einen Blick

  • Mitral regurgitation is a condition where the mitral valve in your heart does not close properly.

  • This causes blood to leak back into the left atrium when the heart pumps.

  • Mild mitral regurgitation often causes no symptoms.

  • More severe cases can cause shortness of breath, tiredness, and swollen ankles.

  • Medicines can help manage symptoms but cannot fix the valve.

  • Surgery to repair or replace the valve may be needed for more severe cases.

  • Treatment can greatly improve the outlook for people with the condition.

The heart - mitral valve incompetence

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What is mitral regurgitation?

Mitral regurgitation is sometimes called mitral insufficiency or mitral incompetence. In mitral regurgitation the valve does not close properly. This causes blood to leak back (regurgitate) into the left atrium when the left ventricle squeezes (contracts). Basically, the more open the valve remains, the more blood regurgitates and the more severe the problem.

Mitralklappenprolaps

This is also called floppy mitral valve. In this condition the valve is slightly deformed and bulges back into the left atrium when the ventricle contracts. This can let a small amount of blood leak back into the left atrium.

As many as 1 in 10 people have some degree of mitral valve prolapse. It becomes common with increasing age. It usually causes no symptoms, as the amount of blood that leaks back is often slight.

What causes mitral regurgitation?

Sometimes regurgitation is rarely caused by congenital structural deformity of or damage to the leaflets, chordae, and/or papillary heart muscles. It sometimes occurs with connective tissue disorders such as Marfan's syndrome, systemischer Lupus erythematodes oder Ehler's-Danlos syndrome.

Rheumatische Herzkrankheit is very common in the developing world and is a common cause of mitral regurgitation worldwide.

Mitral regurgitation symptoms

Mild mitral regurgitation may not cause any symptoms. However the symptoms associated with more severe mitral regurgitation include:

Mitral regurgitation treatment

Mild cases may not require any regular medication. Although medicines cannot correct mitral regurgitation, some medicines may be prescribed to help ease symptoms, or to help prevent complications by managing your blood pressure - for example, Angiotensin-konversionsenzym (ACE)-Hemmer, 'water tablets' (diuretics) und Blutverdünnungsmittel.

If you develop Vorhofflimmern, several medicines can be used to slow the heart rate down.

Chirurgische Behandlung

Surgical treatment is sometimes needed. Recent guidelines favour surgery at an earlier stage than used to be the case. The best option for you will depend on your particular circumstances.

  • Valve repair may be an option in some cases.

  • Valve replacement is needed in some cases. This may be with a mechanical or a tissue valve. Mechanical valves are made of materials which are not likely to react with your body, such as titanium. Tissue valves are made from treated animal tissue, such as valves from a pig.

  • Some surgical options may be possible through a catheter into the femoral vein. This avoids open heart surgery.

Recent guidelines favour replacement rather than repair in many cases. If you need surgery, a surgeon will advise on which is the best option for your situation.

What is the outlook for people with mitral regurgitation?

In some cases, the disorder is mild and causes no symptoms. If you develop symptoms they tend to become gradually worse over the years. Typical complications include Herzinsuffizienz, pulmonary artery hypertension, Vorhofflimmern und Schlaganfall. However, the speed of decline can vary. In many cases, it can take years for symptoms to become serious. Doctors use indications of how serious these complications are to decide when the best time is to refer for possible surgery. For example, when the pressure in the pulmonary artery rises above 60mmHg during exercise testing. Medication can ease symptoms but cannot repair a damaged valve.

Surgical treatment has greatly improved the outlook in most people with more severe regurgitation. Surgery has a very good success rate.

Häufig gestellte Fragen

What is the difference between mitral regurgitation and mitral valve prolapse?

Mitral regurgitation means the mitral valve doesn't close properly, causing blood to leak backward into the left atrium when the left ventricle contracts. Mitral valve prolapse, also known as 'floppy mitral valve', is a condition where the valve is slightly deformed and bulges back into the left atrium. While mitral valve prolapse can cause a small amount of blood to leak back, leading to mitral regurgitation, they are distinct conditions.

Can mitral regurgitation be caused by conditions other than heart problems?

Yes, although rare, mitral regurgitation can sometimes be linked to congenital structural deformities of the valve components. It can also occur in individuals with some connective tissue disorders like Marfan's syndrome, systemic lupus erythematosus, or Ehlers-Danlos syndrome.

If I have mild mitral regurgitation and no symptoms, do I still need treatment?

Mild cases of mitral regurgitation may not require regular medication. While medicines cannot correct the valve problem, they can help manage symptoms or prevent complications, such as by controlling blood pressure, if needed.

What are the different types of valves used in surgical replacement?

When valve replacement surgery is needed, you might receive either a mechanical valve or a tissue valve. Mechanical valves are made from durable materials like titanium, designed not to react with your body. Tissue valves are crafted from treated animal tissue, such as valves sourced from pigs.

What factors do doctors consider when deciding if surgery is necessary for mitral regurgitation?

Doctors consider the severity of complications, such as heart failure, pulmonary artery hypertension, atrial fibrillation, and stroke, when determining the best time to refer for potential surgery. For instance, if the pressure in the pulmonary artery rises above 60mmHg during exercise testing, it suggests a need for intervention.

Weiterführende Literatur und Referenzen

Über den AutorVollständige Biografie anzeigen

Autorenbild

Dr Hayley Willacy, FRCGP

Allgemeinmediziner, Medizinischer Autor

MBChB (1992), DRCOG, DFFP, MRCOG (Part 1) MRCGP (2007), DFSRH (2013), MSc - medical education (2020)

Dr. Hayley Willacy war eine NHS-Hausärztin, die in Nordwestengland arbeitete und 2022 nach 30 Jahren aus der klinischen Praxis ausschied. 

Über den RezensentenVollständige Biografie anzeigen

Autorenbild

Dr Colin Tidy, MRCGP

Allgemeinmediziner, Medizinischer Autor

MBBS, MRCGP, MRCP (Paediatrics), DCH

Dr. Colin Tidy ist ein NHS-Arzt mit Sitz in Oxfordshire.

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